Reactome Pathway Database

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BioModels Database:BIOMD0000000883 Show undefined attributes

created [InstanceEdit:12757879] Weiser, Joel, 2025年08月05日

databaseName BioModels Database

dbId 12757884

displayName BioModels Database:BIOMD0000000883

identifier BIOMD0000000883

referenceDatabase [ReferenceDatabase:12757881] BioModels Database

schemaClass DatabaseIdentifier

url https://www.ebi.ac.uk/biomodels/BIOMD0000000883

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(crossReference)

[Pathway:R-HSA-5621575] CD209 (DC-SIGN) signaling
[Pathway:R-HSA-9028335] Activated NTRK2 signals through PI3K
[Pathway:R-HSA-9665251] Resistance of ERBB2 KD mutants to lapatinib
[Pathway:R-HSA-6802952] Signaling by BRAF and RAF1 fusions
[Pathway:R-HSA-209560] NF-kB is activated and signals survival
[Pathway:R-HSA-1236382] Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
[Pathway:R-HSA-9665233] Resistance of ERBB2 KD mutants to trastuzumab
[Pathway:R-HSA-5654720] PI-3K cascade:FGFR4
[Pathway:R-HSA-1169091] Activation of NF-kappaB in B cells
[Pathway:R-HSA-5654710] PI-3K cascade:FGFR3
[Pathway:R-HSA-9732724] IFNG signaling activates MAPKs
[Pathway:R-HSA-5602636] IKBKB deficiency causes SCID
[Pathway:R-HSA-168164] Toll Like Receptor 3 (TLR3) Cascade
[Pathway:R-HSA-2424491] DAP12 signaling
[Pathway:R-HSA-5674400] Constitutive Signaling by AKT1 E17K in Cancer
[Pathway:R-HSA-177929] Signaling by EGFR
[Pathway:R-HSA-5654695] PI-3K cascade:FGFR2
[Pathway:R-HSA-5673001] RAF/MAP kinase cascade
[Pathway:R-HSA-9665348] Signaling by ERBB2 ECD mutants
[Pathway:R-HSA-5603027] IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)
[Pathway:R-HSA-1810476] RIP-mediated NFkB activation via ZBP1
[Pathway:R-HSA-5655332] Signaling by FGFR3 in disease
[Pathway:R-HSA-6811558] PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
[Pathway:R-HSA-5357956] TNFR1-induced NF-kappa-B signaling pathway
[Pathway:R-HSA-5675482] Regulation of necroptotic cell death
[Pathway:R-HSA-198323] AKT phosphorylates targets in the cytosol
[Pathway:R-HSA-445989] TAK1-dependent IKK and NF-kappa-B activation
[Pathway:R-HSA-5654219] Phospholipase C-mediated cascade: FGFR1
[Pathway:R-HSA-5654693] FRS-mediated FGFR1 signaling
[Pathway:R-HSA-9665247] Resistance of ERBB2 KD mutants to osimertinib
[Pathway:R-HSA-5654689] PI-3K cascade:FGFR1
[Pathway:R-HSA-75893] TNF signaling
[Pathway:R-HSA-9665244] Resistance of ERBB2 KD mutants to sapitinib
[Pathway:R-HSA-5637810] Constitutive Signaling by EGFRvIII
[Pathway:R-HSA-9634285] Constitutive Signaling by Overexpressed ERBB2
[Pathway:R-HSA-9665249] Resistance of ERBB2 KD mutants to afatinib
[Pathway:R-HSA-6802946] Signaling by moderate kinase activity BRAF mutants
[Pathway:R-HSA-9656223] Signaling by RAF1 mutants
[Pathway:R-HSA-5654699] SHC-mediated cascade:FGFR2
[Pathway:R-HSA-5654712] FRS-mediated FGFR4 signaling
[Pathway:R-HSA-937041] IKK complex recruitment mediated by RIP1
[Pathway:R-HSA-180336] SHC1 events in EGFR signaling
[CellLineagePath:R-HSA-9927432] Developmental Lineage of Mammary Gland Myoepithelial Cells
[Pathway:R-HSA-1839122] Signaling by activated point mutants of FGFR1
[Pathway:R-HSA-5654687] Downstream signaling of activated FGFR1
[Pathway:R-HSA-2871796] FCERI mediated MAPK activation
[Pathway:R-HSA-112399] IRS-mediated signalling
[Pathway:R-HSA-9664565] Signaling by ERBB2 KD Mutants
[Pathway:R-HSA-199418] Negative regulation of the PI3K/AKT network
[Pathway:R-HSA-9726842] Gain-of-function MRAS complexes activate RAF signaling
[Pathway:R-HSA-5654688] SHC-mediated cascade:FGFR1
[Pathway:R-HSA-9726840] SHOC2 M1731 mutant abolishes MRAS complex function
[Pathway:R-HSA-9665686] Signaling by ERBB2 TMD/JMD mutants
[Pathway:R-HSA-5213460] RIPK1-mediated regulated necrosis
[Pathway:R-HSA-9665245] Resistance of ERBB2 KD mutants to tesevatinib
[Pathway:R-HSA-9665737] Drug resistance in ERBB2 TMD/JMD mutants
[Pathway:R-HSA-8847993] ERBB2 Activates PTK6 Signaling
[Pathway:R-HSA-389356] Co-stimulation by CD28
[Pathway:R-HSA-5654719] SHC-mediated cascade:FGFR4
[Pathway:R-HSA-5218920] VEGFR2 mediated vascular permeability
[Pathway:R-HSA-354194] GRB2:SOS provides linkage to MAPK signaling for Integrins
[Pathway:R-HSA-5357905] Regulation of TNFR1 signaling
[Pathway:R-HSA-109704] PI3K Cascade
[Pathway:R-HSA-9665250] Resistance of ERBB2 KD mutants to AEE788
[Pathway:R-HSA-212718] EGFR interacts with phospholipase C-gamma
[Pathway:R-HSA-933543] NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
[Pathway:R-HSA-6802955] Paradoxical activation of RAF signaling by kinase inactive BRAF
[Pathway:R-HSA-1963642] PI3K events in ERBB2 signaling
[Pathway:R-HSA-9649948] Signaling downstream of RAS mutants
[Pathway:R-HSA-112412] SOS-mediated signalling
[Pathway:R-HSA-912526] Interleukin receptor SHC signaling
[Pathway:R-HSA-170968] Frs2-mediated activation
[Pathway:R-HSA-8851805] MET activates RAS signaling
[Pathway:R-HSA-6785631] ERBB2 Regulates Cell Motility
[Pathway:R-HSA-1963640] GRB2 events in ERBB2 signaling
[Pathway:R-HSA-8851907] MET activates PI3K/AKT signaling
[Pathway:R-HSA-5674499] Negative feedback regulation of MAPK pathway
[Pathway:R-HSA-5674135] MAP2K and MAPK activation
[Pathway:R-HSA-5654700] FRS-mediated FGFR2 signaling
[Pathway:R-HSA-1250196] SHC1 events in ERBB2 signaling
[Pathway:R-HSA-1251932] PLCG1 events in ERBB2 signaling
[Pathway:R-HSA-202424] Downstream TCR signaling
[Pathway:R-HSA-5603029] IkBA variant leads to EDA-ID
[Pathway:R-HSA-5655302] Signaling by FGFR1 in disease
[Pathway:R-HSA-1839120] Signaling by FGFR1 amplification mutants
[Pathway:R-HSA-190373] FGFR1c ligand binding and activation
[Pathway:R-HSA-5655253] Signaling by FGFR2 in disease
[Pathway:R-HSA-179812] GRB2 events in EGFR signaling
[Pathway:R-HSA-2219530] Constitutive Signaling by Aberrant PI3K in Cancer
[Pathway:R-HSA-9758274] Regulation of NF-kappa B signaling
[Pathway:R-HSA-6802948] Signaling by high-kinase activity BRAF mutants
[Pathway:R-HSA-933542] TRAF6 mediated NF-kB activation
[Pathway:R-HSA-2730905] Role of LAT2/NTAL/LAB on calcium mobilization
[Pathway:R-HSA-5675221] Negative regulation of MAPK pathway
[Pathway:R-HSA-5673000] RAF activation
[Pathway:R-HSA-5654706] FRS-mediated FGFR3 signaling
[Pathway:R-HSA-190370] FGFR1b ligand binding and activation
[Pathway:R-HSA-9652282] Drug-mediated inhibition of ERBB2 signaling
[Pathway:R-HSA-5638303] Inhibition of Signaling by Overexpressed EGFR
[Pathway:R-HSA-9634635] Estrogen-stimulated signaling through PRKCZ
[Pathway:R-HSA-182971] EGFR downregulation
[Pathway:R-HSA-9652169] Signaling by MAP2K mutants
[Pathway:R-HSA-5674404] PTEN Loss of Function in Cancer
[Pathway:R-HSA-5654704] SHC-mediated cascade:FGFR3
[Pathway:R-HSA-165158] Activation of AKT2
[Pathway:R-HSA-168927] TICAM1, RIP1-mediated IKK complex recruitment
[Pathway:R-HSA-389357] CD28 dependent PI3K/Akt signaling
[Pathway:R-HSA-180292] GAB1 signalosome
[Pathway:R-HSA-9665246] Resistance of ERBB2 KD mutants to neratinib
[Pathway:R-HSA-5684264] MAP3K8 (TPL2)-dependent MAPK1/3 activation
[Pathway:R-HSA-166166] MyD88-independent TLR4 cascade
[Pathway:R-HSA-1227986] Signaling by ERBB2
[Pathway:R-HSA-5357786] TNFR1-induced proapoptotic signaling
[Pathway:R-HSA-5218900] CASP8 activity is inhibited

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