Reactome Pathway Database

Schema > Pathway > Entries

Resistance of ERBB2 KD mutants to tesevatinib Show undefined attributes

authored

[InstanceEdit:9665241] Orlic-Milacic, Marija, 2019年10月30日

created [InstanceEdit:9665248] Orlic-Milacic, Marija, 2019年10月30日

crossReference

dbId 9665245

disease

[Disease:1500689] cancer

displayName Resistance of ERBB2 KD mutants to tesevatinib

edited

[InstanceEdit:9665760] Orlic-Milacic, Marija, 2019年11月01日

eventOf

[Pathway:R-HSA-9665230] Drug resistance in ERBB2 KD mutants - Homo sapiens

hasDiagram true

hasEHLD false

hasEvent

[FailedReaction:R-HSA-9665315] ERBB2 T733I does not bind tesevatinib - Homo sapiens

isInDisease true

isInferred false

literatureReference

[LiteratureReference:9646776] EXEL-7647 inhibits mutant forms of ErbB2 associated with lapatinib resistance and neoplastic transformation

maxDepth 2

modified [InstanceEdit:12757879] Weiser, Joel, 2025年08月05日

name

Resistance of ERBB2 KD mutants to tesevatinib

normalPathway [Pathway:R-HSA-1227986] Signaling by ERBB2

releaseDate 2019年12月10日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:9662685] Kancha, Rama Krishna, 2019年09月16日

schemaClass Pathway

species

[Species:48887] Homo sapiens

stId R-HSA-9665245

summation

[Summation:9665260] This pathway describes resistance of ERBB2 KD mutants to tyr...

Referrals

(hasEvent)

[Pathway:R-HSA-9665230] Drug resistance in ERBB2 KD mutants

© 2025 Reactome

Cite Us!