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Paradoxical activation of RAF signaling by kinase inactive BRAF Show undefined attributes

authored

[InstanceEdit:6802811] Rothfels, Karen, 2015年08月10日

created [InstanceEdit:6802956] Rothfels, Karen, 2015年10月02日

crossReference

dbId 6802955

disease

[Disease:1500689] cancer

displayName Paradoxical activation of RAF signaling by kinase inactive BRAF

edited

[InstanceEdit:5693873] Rothfels, Karen, 2015年05月18日

eventOf

[Pathway:R-HSA-6802957] Oncogenic MAPK signaling - Homo sapiens

hasDiagram true

hasEHLD false

hasEvent

isInDisease true

isInferred false

lastUpdatedDate 2020年06月17日

literatureReference

maxDepth 2

modified [InstanceEdit:12757879] Weiser, Joel, 2025年08月05日

name

Paradoxical activation of RAF signaling by kinase inactive BRAF

normalPathway [Pathway:R-HSA-5673001] RAF/MAP kinase cascade

releaseDate 2016年09月19日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:8933498] Stephens, Robert M, 2016年08月05日

schemaClass Pathway

species

[Species:48887] Homo sapiens

stId R-HSA-6802955

summation

[Summation:6802247] While BRAF-specific inhibitors inhibit MAPK/ERK activation i...

updateTrackers

[UpdateTracker:9777064] Update Tracker - [Pathway:6802955] Paradoxical activation of RAF signaling by kinase inactive BRAF - v73:[addLiteratureReference, modifyText]

Referrals

(hasEvent)

[Pathway:R-HSA-6802957] Oncogenic MAPK signaling

(updatedInstance)

[UpdateTracker:9777064] Update Tracker - [Pathway:6802955] Paradoxical activation of RAF signaling by kinase inactive BRAF - v73:[addLiteratureReference, modifyText]

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