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Reactome Pathway Database
About
What is Reactome ?
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Schema
>
DatabaseIdentifier
>
Entries
Mondo:0100096
Show undefined attributes
databaseName
Mondo
dbId
11944893
displayName
Mondo:0100096
identifier
0100096
referenceDatabase
[ReferenceDatabase:11944889] Mondo
schemaClass
DatabaseIdentifier
url
https://monarchinitiative.org/MONDO:0100096
Referrals
(crossReference)
[Reaction:R-HSA-9694304] nsp14 binds nsp12
[ChemicalDrug:R-ALL-9731197] PF-00835231 [cytosol]
[DefinedSet:R-ALL-9731705] 3CLp inhibitors [cytosol]
[ChemicalDrug:R-ALL-9731712] ebselen [cytosol]
[EntityWithAccessionedSequence:R-COV-9694729] O-glycosyl 3a [endocytic vesicle membrane]
[Complex:R-COV-9694756] complex N-glycan-PALM-Spike S2 fragment trimer [endocytic vesicle membrane]
[EntityWithAccessionedSequence:R-COV-9694778] pp1a-nsp1-4 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694745] complex N-glycan-PALM-Spike S1 Fragment [endocytic vesicle membrane]
[Complex:R-COV-9694413] complex N-glycan-PALM-Spike S2 fragment trimer [virion membrane]
[EntityWithAccessionedSequence:R-COV-9697431] m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid]
[EntityWithAccessionedSequence:R-COV-9694320] M [virion membrane]
[EntityWithAccessionedSequence:R-COV-9694638] complex N-glycan-PALM-Spike S1 Fragment [virion membrane]
[EntityWithAccessionedSequence:R-COV-9694645] 7a [endocytic vesicle membrane]
[Complex:R-HSA-9755778] N:M:PDPK1 [plasma membrane]
[Complex:R-COV-9694585] S1:S2:M:E:encapsidated SARS-CoV-2 genomic RNA: 7a:O-glycosyl 3a tetramer [endocytic vesicle lumen]
[Complex:R-COV-9694783] S1:S2:M lattice:E protein [virion membrane]
[ChemicalDrug:R-ALL-9767462] heparin [extracellular region]
[EntityWithAccessionedSequence:R-COV-9694668] pp1a-nsp6-11 [cytosol]
[Complex:R-COV-9694776] 7a:O-glycosyl 3a tetramer [endocytic vesicle membrane]
[Complex:R-COV-9698417] Ub-3xPalmC-E pentamer [virion membrane]
[Complex:R-COV-9694534] S1:S2:M:E: 7a:O-glycosyl 3a tetramer [endocytic vesicle membrane]
[Complex:R-COV-9698421] Ub-3xPalmC-E pentamer [endocytic vesicle membrane]
[Complex:R-COV-9694552] M lattice [endocytic vesicle membrane]
[Complex:R-COV-9694714] S3:M lattice:E protein [virion membrane]
[EntityWithAccessionedSequence:R-COV-9694395] O-glycosyl 3a [virion membrane]
[Complex:R-COV-9698338] fully glycosylated Spike trimer [virion membrane]
[Complex:R-COV-9694698] M lattice [virion membrane]
[Complex:R-COV-9694781] O-glycosyl 3a tetramer [endocytic vesicle membrane]
[EntityWithAccessionedSequence:R-COV-9694563] M [endocytic vesicle membrane]
[Complex:R-HSA-9755745] N:TAK1complex [cytosol]
[DefinedSet:R-COV-9694748] nsp5 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694385] N-glycan M [virion membrane]
[Complex:R-COV-9694427] 7a:O-glycosyl 3a tetramer [virion membrane]
[Complex:R-COV-9694421] complex N-glycan-PALM-Spike S1 fragment trimer [virion membrane]
[EntityWithAccessionedSequence:R-COV-9694343] complex N-glycan-PALM-Spike S2 Fragment [endocytic vesicle membrane]
[EntityWithAccessionedSequence:R-COV-9681994] pp1a-3CL [cytosol]
[Complex:R-COV-9694268] O-glycosyl 3a tetramer [virion membrane]
[Complex:R-COV-9697428] encapsidated SARS-CoV-2 genomic RNA [viral capsid]
[EntityWithAccessionedSequence:R-COV-9729340] SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol]
[EntityWithAccessionedSequence:R-COV-9694738] N-glycan M [endocytic vesicle membrane]
[EntityWithAccessionedSequence:R-COV-9694648] 7a [virion membrane]
[Complex:R-COV-9697429] N dimer [viral capsid]
[EntityWithAccessionedSequence:R-COV-9698416] Ub-3xPalmC-E [virion membrane]
[Complex:R-COV-9694474] S1:S2:M lattice:E protein [endocytic vesicle membrane]
[Complex:R-HSA-9729808] 7SL RNA:nsp8 [cytosol]
[EntityWithAccessionedSequence:R-COV-9682052] pp1ab-nsp8 [cytosol]
[Complex:R-COV-9694500] S3:M:E:encapsidated SARS-CoV-2 genomic RNA: 7a:O-glycosyl 3a tetramer [extracellular region]
[Complex:R-COV-9694702] N dimer [cytosol]
[EntityWithAccessionedSequence:R-COV-9755780] M [plasma membrane]
[EntityWithAccessionedSequence:R-COV-9698422] Ub-3xPalmC-E [endocytic vesicle membrane]
[EntityWithAccessionedSequence:R-COV-9694393] m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol]
[ChemicalDrug:R-ALL-9731691] boceprevir [cytosol]
[Complex:R-COV-9694407] 3CLp dimer [cytosol]
[EntityWithAccessionedSequence:R-COV-9694504] pp1ab-nsp5 [cytosol]
[EntityWithAccessionedSequence:R-COV-9681992] pp1a-nsp8 [cytosol]
[Complex:R-COV-9694461] encapsidated SARS-CoV-2 genomic RNA (plus strand) [cytosol]
[ChemicalDrug:R-ALL-9731198] nirmatrelvir [cytosol]
[EntityWithAccessionedSequence:R-COV-9698327] fully glycosylated Spike [virion membrane]
[DefinedSet:R-COV-9691351] nsp8 [cytosol]
[Complex:R-HSA-9694785] S3:M:E:encapsidated SARS-CoV-2 genomic RNA: 7a:O-glycosyl 3a tetramer:glycosylated-ACE2:HSPGs [extracellular region]
[EntityWithAccessionedSequence:R-COV-9729341] SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane]
[EntityWithAccessionedSequence:R-COV-9681986] pp1a [cytosol]
[Complex:R-COV-9694606] complex N-glycan-PALM-Spike S1 fragment trimer [endocytic vesicle membrane]
[Complex:R-HSA-9755930] N:CHUK:IKBKB:IKBKG [cytosol]
[EntityWithAccessionedSequence:R-COV-9694791] complex N-glycan-PALM-Spike S2 Fragment [virion membrane]
[Complex:R-COV-9694375] 3CLp dimer:3CLp inhibitors [cytosol]
[EntityWithAccessionedSequence:R-COV-9694352] m7G(5')pppAm-mRNA5 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694642] pp1ab-nsp13 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694456] m7G(5')pppAm-capped,polyadenylated mRNA5 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694264] mRNA4 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694484] m7GpppA-mRNA2 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694777] pp1ab-nsp6 [double membrane vesicle viral factory outer membrane]
[EntityWithAccessionedSequence:R-COV-9694350] m7G(5')pppAm-mRNA8 [cytosol]
[Complex:R-COV-9691364] nsp7:nsp8:nsp12 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694771] m7GpppA-mRNA8 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694716] 3a [endoplasmic reticulum-Golgi intermediate compartment]
[EntityWithAccessionedSequence:R-COV-9694675] m7GpppA-mRNA3 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694587] m7GpppA-mRNA5 [cytosol]
[DefinedSet:R-COV-9694711] m7GpppA-SARS-CoV-2 plus strand subgenomic mRNAs [cytosol]
[Complex:R-COV-9694717] nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694266] m7G(5')pppAm-mRNA3 [cytosol]
[DefinedSet:R-COV-9694770] nsp6 [double membrane vesicle viral factory outer membrane]
[EntityWithAccessionedSequence:R-COV-9694647] pp1ab-nsp16 [cytosol]
[DefinedSet:R-COV-9765944] N6GMPLys-nsp7 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694607] pp1ab-nsp4 [double membrane vesicle viral factory outer membrane]
[EntityWithAccessionedSequence:R-COV-9694372] pp1ab-nsp10 [cytosol]
[Complex:R-COV-9698996] M lattice [plasma membrane]
[EntityWithAccessionedSequence:R-COV-9694386] O-glycosyl 3a [endoplasmic reticulum-Golgi intermediate compartment membrane]
[EntityWithAccessionedSequence:R-COV-9694767] pp1a-nsp4 [double membrane vesicle viral factory outer membrane]
[Complex:R-COV-9694688] nsp10:nsp14 [cytosol]
[EntityWithAccessionedSequence:R-COV-9765953] N6GMPLys-pp1a-nsp7 [cytosol]
[Complex:R-COV-9694324] S3:M:E:encapsidated SARS-CoV-2 genomic RNA:7a:O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane]
[DefinedSet:R-COV-9694561] m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 subgenomic mRNAs (plus strand) [cytosol]
[EntityWithAccessionedSequence:R-COV-9694384] m7GpppA-mRNA7 [cytosol]
[DefinedSet:R-COV-9694470] nsp3 [double membrane vesicle viral factory outer membrane]
[Complex:R-COV-9694502] S3:M lattice:E protein [endoplasmic reticulum-Golgi intermediate compartment membrane]
[Complex:R-COV-9694416] nsp16:nsp10 [cytosol]
[Complex:R-COV-9698995] S2 trimer [plasma membrane]
[Complex:R-COV-9698334] fully glycosylated Spike trimer [endoplasmic reticulum-Golgi intermediate compartment membrane]
[EntityWithAccessionedSequence:R-COV-9698420] Ub-3xPalmC-E [endoplasmic reticulum-Golgi intermediate compartment membrane]
[EntityWithAccessionedSequence:R-COV-9765943] N6GMPLys-pp1ab-nsp7 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694410] mRNA7a [cytosol]
[Complex:R-COV-9694597] nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol]
[EntityWithAccessionedSequence:R-COV-9681983] pp1a-nsp10 [cytosol]
[DefinedSet:R-COV-9694701] SARS-CoV-2 plus strand subgenomic mRNAs [cytosol]
[Complex:R-COV-9698989] Ub-3xPalmC-E pentamer [plasma membrane]
[Complex:R-COV-9771682] nsp12:2Fe4S4 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694335] pp1ab-nsp15 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694513] m7G(5')pppAm-capped,polyadenylated-mRNA9 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694699] m7G(5')pppAm-mRNA4 [cytosol]
[Complex:R-COV-9694590] 7a:O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane]
[EntityWithAccessionedSequence:R-COV-9694496] m7G(5')pppAm-capped,polyadenylated mRNA7 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694430] pp1ab-nsp3 [double membrane vesicle viral factory outer membrane]
[EntityWithAccessionedSequence:R-COV-9682057] pp1ab-nsp12 [cytosol]
[Complex:R-COV-9694598] O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane]
[EntityWithAccessionedSequence:R-COV-9694582] mRNA3 [cytosol]
[EntityWithAccessionedSequence:R-COV-9792628] GpppAm-mRNA5 [cytosol]
[Complex:R-COV-9698997] S1:S2:M lattice:E protein [plasma membrane]
[Complex:R-COV-9713653] SARS-CoV-2 plus strand subgenomic mRNAs:RTC [double membrane vesicle viral factory outer membrane]
[EntityWithAccessionedSequence:R-COV-9694354] m7G(5')pppAm-capped,polyadenylated mRNA8 [cytosol]
[Complex:R-COV-9752958] S3:M:E:encapsidated SARS-CoV-2 genomic RNA: 7a:O-glycosyl 3a tetramer [exocytic vesicle]
[EntityWithAccessionedSequence:R-COV-9694285] m7G(5')pppAm-capped,polyadenylated mRNA6 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694720] pp1a-nsp3 [double membrane vesicle viral factory outer membrane]
[EntityWithAccessionedSequence:R-COV-9694546] mRNA5 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694663] m7GpppA-mRNA9 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694460] mRNA2 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694260] mRNA8 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694622] m7G(5')pppAm-capped,polyadenylated mRNA4 [cytosol]
[Complex:R-COV-9698418] Ub-3xPalmC-E pentamer [endoplasmic reticulum-Golgi intermediate compartment membrane]
[EntityWithAccessionedSequence:R-COV-9694710] m7G(5')pppAm-mRNA7 [cytosol]
[DefinedSet:R-COV-9694481] nsp4 [double membrane vesicle viral factory outer membrane]
[EntityWithAccessionedSequence:R-COV-9694703] m7GpppA-mRNA4 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694658] GalNAc-O-3a [endoplasmic reticulum-Golgi intermediate compartment]
[ProteinDrug:R-ALL-9733131] etesevimab [extracellular region]
[EntityWithAccessionedSequence:R-COV-9694446] N-glycan M [endoplasmic reticulum-Golgi intermediate compartment membrane]
[EntityWithAccessionedSequence:R-COV-9694750] 7a [endoplasmic reticulum-Golgi intermediate compartment membrane]
[EntityWithAccessionedSequence:R-COV-9694490] mRNA6 [cytosol]
[Complex:R-COV-9698986] complex N-glycan-PALM-Spike S1 fragment trimer [plasma membrane]
[EntityWithAccessionedSequence:R-COV-9697251] mRNA7b [cytosol]
[Complex:R-COV-9694366] nsp3:nsp4 [double membrane vesicle viral factory outer membrane]
[EntityWithAccessionedSequence:R-COV-9694382] mRNA9 [cytosol]
[Complex:R-COV-9694728] nsp3:nsp4:nsp6 [double membrane vesicle viral factory outer membrane]
[Complex:R-COV-9694612] encapsidated SARS-CoV-2 genomic RNA [endoplasmic reticulum-Golgi intermediate compartment membrane]
[Complex:R-COV-9694573] N dimer [endoplasmic reticulum-Golgi intermediate compartment membrane]
[EntityWithAccessionedSequence:R-COV-9694757] m7G(5')pppAm-mRNA6 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694523] m7G(5')pppAm-mRNA9 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694439] M [endoplasmic reticulum-Golgi intermediate compartment membrane]
[EntityWithAccessionedSequence:R-COV-9694584] 3a [endoplasmic reticulum lumen]
[EntityWithAccessionedSequence:R-COV-9694503] m7G(5')pppAm-capped,polyadenylated mRNA2 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694325] m7G(5')pppAm-capped,polyadenylated mRNA3 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694537] pp1ab-nsp14 [cytosol]
[EntityWithAccessionedSequence:R-COV-9792630] GpppAm-mRNA4 [cytosol]
[Complex:R-COV-9694321] S3:M:E:encapsidated SARS-CoV-2 genomic RNA:O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane]
[Complex:R-COV-9694371] M lattice [endoplasmic reticulum-Golgi intermediate compartment membrane]
[EntityWithAccessionedSequence:R-COV-9694292] m7GpppA-mRNA6 [cytosol]
[ProteinDrug:R-ALL-9733136] bamlanivimab [extracellular region]
[DefinedSet:R-COV-9694358] nsp10 [cytosol]
[Complex:R-COV-9713651] m7GpppA-SARS-CoV-2 plus strand subgenomic mRNAs:RTC [double membrane vesicle viral factory outer membrane]
[Complex:R-COV-9694570] nsp15 hexamer [cytosol]
[Complex:R-COV-9694302] RTC [double membrane vesicle viral factory outer membrane]
[Complex:R-COV-9691348] nsp7:nsp8 [cytosol]
[DefinedSet:R-COV-9694259] m7G(5')pppAm-SARS-CoV-2 plus strand subgenomic mRNAs [cytosol]
[EntityWithAccessionedSequence:R-COV-9698330] fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment membrane]
[EntityWithAccessionedSequence:R-COV-9694613] m7G(5')pppAm-mRNA2 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694615] pp1a-nsp6 [double membrane vesicle viral factory outer membrane]
[Complex:R-COV-9694740] nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol]
[DefinedSet:R-COV-9694569] N-glycan nsp4 [endoplasmic reticulum membrane]
[EntityWithAccessionedSequence:R-COV-9694746] N-glycan pp1ab-nsp3 [endoplasmic reticulum membrane]
[DefinedSet:R-COV-9694577] nsp4 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694425] pp1ab-nsp6 [endoplasmic reticulum membrane]
[EntityWithAccessionedSequence:R-COV-9694603] m7G(5')pppAm-capped SARS-CoV-2 genomic RNA complement (minus strand) [cytosol]
[EntityWithAccessionedSequence:R-COV-9729264] p-11S,2T-N [cytosol]
[EntityWithAccessionedSequence:R-COV-9694468] pp1a-nsp3-4 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694511] mRNA6 minus strand [cytosol]
[EntityWithAccessionedSequence:R-COV-9694652] N-glycan pp1ab-nsp4 [endoplasmic reticulum membrane]
[Complex:R-COV-9792635] GpppA-SARS-CoV-2 plus strand subgenomic mRNAs:RTC [double membrane vesicle viral factory outer membrane]
[EntityWithAccessionedSequence:R-COV-9792638] GpppAm-mRNA6 [cytosol]
[DefinedSet:R-COV-9694554] nsp3-4 [cytosol]
[DefinedSet:R-COV-9691334] nsp7 [cytosol]
[EntityWithAccessionedSequence:R-COV-9697259] mRNA7b minus strand [cytosol]
[EntityWithAccessionedSequence:R-COV-9694347] mRNA2 minus strand [cytosol]
[Complex:R-COV-9694458] SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane]
[Complex:R-COV-9694491] M lattice:E protein:encapsidated SARS-CoV-2 genomic RNA [endoplasmic reticulum-Golgi intermediate compartment membrane]
[EntityWithAccessionedSequence:R-COV-9694763] N-glycan pp1a-nsp4 [endoplasmic reticulum membrane]
[EntityWithAccessionedSequence:R-COV-9792632] GpppAm-mRNA2 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694588] mRNA8 minus strand [cytosol]
[EntityWithAccessionedSequence:R-COV-9694315] N-glycan pp1a-nsp3 [endoplasmic reticulum membrane]
[Complex:R-COV-9694725] SARS-CoV-2 gRNA:RTC:RNA primer [double membrane vesicle viral factory outer membrane]
[DefinedSet:R-COV-9694501] SARS-CoV-2 minus strand subgenomic mRNAs [cytosol]
[EntityWithAccessionedSequence:R-COV-9729308] p-11S,2T-metR95,177-N [cytosol]
[Complex:R-COV-9713643] m7GpppA-capped SARS-CoV-2 genomic RNA (plus strand):RTC [double membrane vesicle viral factory outer membrane]
[EntityWithAccessionedSequence:R-COV-9694300] N [cytosol]
[DefinedSet:R-COV-9694784] nsp1-4 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694279] nascent M [endoplasmic reticulum lumen]
[EntityWithAccessionedSequence:R-COV-9694339] SARS-CoV-2 genomic RNA (plus strand) [cytosol]
[Complex:R-COV-9697197] fully glycosylated Spike trimer [endoplasmic reticulum-Golgi intermediate compartment]
[Complex:R-COV-9694743] pp1a dimer [cytosol]
[EntityWithAccessionedSequence:R-COV-9792637] GpppAm-mRNA3 [cytosol]
[EntityWithAccessionedSequence:R-COV-9792633] GpppAm-mRNA7 [cytosol]
[DefinedSet:R-COV-9694361] nsp6 [endoplasmic reticulum membrane]
[EntityWithAccessionedSequence:R-COV-9681988] pp1a-nsp2 [cytosol]
[Complex:R-HSA-9694758] S3:M:E:encapsidated SARS-CoV-2 genomic RNA: 7a:O-glycosyl 3a tetramer:glycosylated-ACE2 [endocytic vesicle lumen]
[Complex:R-COV-9694618] SARS-CoV-2 gRNA:RTC:nascent RNA minus strand [double membrane vesicle viral factory outer membrane]
[DefinedSet:R-COV-9694741] nsp1 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694497] pp1ab-nsp4 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694687] Ub-3xPalmC-E [Golgi membrane]
[Complex:R-COV-9694255] SARS-CoV-2 gRNA:RTC:RNA primer:RTC inhibitors [double membrane vesicle viral factory outer membrane]
[EntityWithAccessionedSequence:R-COV-9682068] pp1ab [cytosol]
[Complex:R-COV-9754528] O-glycosyl 3a tetramer [endolysosome membrane]
[EntityWithAccessionedSequence:R-COV-9754541] O-glycosyl 3a [endolysosome membrane]
[EntityWithAccessionedSequence:R-COV-9694708] SARS-CoV-2 genomic RNA complement (minus strand) [cytosol]
[Complex:R-COV-9713634] m7GpppA-capped SARS-CoV-2 genomic RNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane]
[EntityWithAccessionedSequence:R-COV-9694278] m7GpppA-capped SARS-CoV-2 genomic RNA complement (minus strand) [cytosol]
[Complex:R-COV-9713636] SARS-CoV-2 genomic RNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane]
[EntityWithAccessionedSequence:R-COV-9694559] N-glycan pp1a-nsp3-4 [endoplasmic reticulum membrane]
[EntityWithAccessionedSequence:R-COV-9729277] p-8S,2T-N [cytosol]
[EntityWithAccessionedSequence:R-COV-9694695] pp1ab-nsp1-4 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694412] pp1ab-nsp1 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694515] pp1ab-nsp2 [cytosol]
[EntityWithAccessionedSequence:R-COV-9682061] pp1ab-nsp7 [cytosol]
[Complex:R-COV-9694664] M lattice:E protein [endoplasmic reticulum-Golgi intermediate compartment membrane]
[Complex:R-COV-9694402] SUMO-p-N dimer:SARS-CoV-2 genomic RNA [endoplasmic reticulum-Golgi intermediate compartment membrane]
[EntityWithAccessionedSequence:R-COV-9681991] pp1a-nsp9 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694712] m7GpppA-capped SARS-CoV-2 genomic RNA (plus strand) [cytosol]
[DefinedSet:R-COV-9792631] GpppA-SARS-CoV-2 plus strand subgenomic mRNAs [cytosol]
[EntityWithAccessionedSequence:R-COV-9694550] mRNA9 minus strand [cytosol]
[EntityWithAccessionedSequence:R-COV-9694684] N-glycan M [endoplasmic reticulum membrane]
[EntityWithAccessionedSequence:R-COV-9681984] pp1a-nsp4 [cytosol]
[Complex:R-COV-9713652] SARS-CoV-2 minus strand subgenomic mRNAs:RTC [double membrane vesicle viral factory outer membrane]
[EntityWithAccessionedSequence:R-COV-9681990] pp1a-nsp11 [cytosol]
[EntityWithAccessionedSequence:R-COV-9697006] tri-antennary N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment]
[EntityWithAccessionedSequence:R-COV-9694629] mRNA7a minus strand [cytosol]
[Complex:R-COV-9694327] SARS-CoV-2 gRNA:RTC:nascent RNA minus strand:RTC inhibitors [double membrane vesicle viral factory outer membrane]
[EntityWithAccessionedSequence:R-COV-9694755] mRNA4 minus strand [cytosol]
[EntityWithAccessionedSequence:R-COV-9694697] pp1ab-nsp9 [cytosol]
[Complex:R-COV-9694404] SARS-CoV-2 gRNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane]
[EntityWithAccessionedSequence:R-COV-9767620] M [endoplasmic reticulum membrane]
[Complex:R-COV-9694269] SARS coronavirus gRNA:RTC:nascent RNA minus strand with mismatched nucleotide [double membrane vesicle viral factory outer membrane]
[DefinedSet:R-COV-9694735] N-glycan nsp3 [endoplasmic reticulum membrane]
[EntityWithAccessionedSequence:R-COV-9694753] mRNA3 minus strand [cytosol]
[EntityWithAccessionedSequence:R-COV-9729335] p-8S-N [cytosol]
[Complex:R-COV-9694690] SARS-CoV-2 gRNA complement (minus strand):RTC:RTC inhibitors [double membrane vesicle viral factory outer membrane]
[EntityWithAccessionedSequence:R-COV-9694488] SARS-CoV-2 nascent genomic RNA complement (minus strand) [cytosol]
[Complex:R-COV-9713644] SARS-CoV-2 genomic RNA (plus strand):RTC [double membrane vesicle viral factory outer membrane]
[Complex:R-COV-9694408] Ub-3xPalmC-E pentamer [Golgi membrane]
[EntityWithAccessionedSequence:R-COV-9694600] N-glycan pp1ab-nsp3-4 [endoplasmic reticulum membrane]
[EntityWithAccessionedSequence:R-COV-9694256] pp1a-nsp6 [endoplasmic reticulum membrane]
[EntityWithAccessionedSequence:R-COV-9694621] mRNA5 minus strand [cytosol]
[EntityWithAccessionedSequence:R-COV-9681993] pp1a-nsp3 [cytosol]
[EntityWithAccessionedSequence:R-COV-9696997] fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment]
[Complex:R-COV-9694731] SARS coronavirus 2 gRNA with secondary structure:RTC [double membrane vesicle viral factory outer membrane]
[EntityWithAccessionedSequence:R-COV-9694766] pp1ab-nsp3 [cytosol]
[ChemicalDrug:R-ALL-9766614] MS023 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694619] m7G(5')pppAm-capped SARS-CoV-2 genomic RNA (plus strand) [cytosol]
[EntityWithAccessionedSequence:R-COV-9729275] ADPr-p-11S,2T-metR95,177-N [cytosol]
[EntityWithAccessionedSequence:R-COV-9792622] GpppAm-mRNA8 [cytosol]
[EntityWithAccessionedSequence:R-COV-9681995] pp1a-nsp7 [cytosol]
[EntityWithAccessionedSequence:R-COV-9769952] complex N-glycan-PALM-Spike S2 Fragment [plasma membrane]
[DefinedSet:R-COV-9694760] nsp2 [cytosol]
[EntityWithAccessionedSequence:R-COV-9729324] p-S188,206-N [cytosol]
[EntityWithAccessionedSequence:R-COV-9681989] pp1a-nsp1 [cytosol]
[DefinedSet:R-COV-9694479] N-glycan nsp3-4 [endoplasmic reticulum membrane]
[DefinedSet:R-COV-9694428] nsp3 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694434] SARS-CoV-2 nascent genomic RNA complement (minus strand) with mismatched 3' nucleotide [cytosol]
[EntityWithAccessionedSequence:R-COV-9792624] GpppAm-mRNA9 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694533] pp1ab-nsp3-4 [cytosol]
[Complex:R-HSA-9694566] nsp8:MAP1LC3B [cytosol]
[EntityWithAccessionedSequence:R-COV-9755410] 8 [extracellular region]
[Complex:R-HSA-9754834] M:TBK1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
[Complex:R-HSA-9754828] 9b:IKK complex [mitochondrial outer membrane]
[EntityWithAccessionedSequence:R-COV-9696880] high-mannose N-glycan folded Spike [endoplasmic reticulum lumen]
[Complex:R-HSA-9729832] 40S ribosomal complex:nsp1 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694423] Ub-3xPalmC-E [endoplasmic reticulum lumen]
[EntityWithAccessionedSequence:R-COV-9694305] 3xPalmC-E [endoplasmic reticulum lumen]
[Complex:R-COV-9755409] 8 homodimer [extracellular region]
[Complex:R-HSA-9709659] TOMM70:9b [mitochondrial outer membrane]
[EntityWithAccessionedSequence:R-COV-9729339] SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus]
[DefinedSet:R-NUL-9684903] GU-rich ssRNA [endosome lumen]
[Complex:R-HSA-9708891] 6:NPC [nuclear envelope]
[EntityWithAccessionedSequence:R-COV-9754746] SARS-CoV-2 5'-poly(U)-gRNA complement (minus strand) [cytosol]
[Complex:R-HSA-9757077] N:NLRP3 [cytosol]
[Complex:R-COV-9694306] O-glycosyl 3a tetramer [plasma membrane]
[EntityWithAccessionedSequence:R-COV-9727308] 7a [endoplasmic reticulum membrane]
[Complex:R-HSA-9755355] 8:IL17RA [plasma membrane]
[EntityWithAccessionedSequence:R-COV-9758478] p-S53-9b [cytosol]
[Complex:R-COV-9709655] 9b homodimer [mitochondrial outer membrane]
[Complex:R-COV-9694464] N dimer [plasma membrane]
[Complex:R-HSA-9730524] UVRAG:O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane]
[EntityWithAccessionedSequence:R-COV-9696943] high-mannose N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment]
[Complex:R-COV-9694475] 3a:membranous structure [extracellular region]
[ChemicalDrug:R-ALL-9835132] heparin [cytosol]
[EntityWithAccessionedSequence:R-COV-9696892] Man(9) N-glycan unfolded Spike [endoplasmic reticulum lumen]
[Complex:R-HSA-9729785] 7SL RNA:nsp9 tetramer [cytosol]
[Complex:R-HSA-9756571] SFTPD:S3:M:E:encapsidated SARS-CoV-2 genomic RNA: 7a:O-glycosyl 3a tetramer [extracellular region]
[EntityWithAccessionedSequence:R-COV-9708916] 6 [cytosol]
[EntityWithAccessionedSequence:R-COV-9727279] 6 [nuclear envelope]
[Complex:R-HSA-9717677] DDX58:N [cytosol]
[DefinedSet:R-COV-9754749] SARS-CoV-2 dsRNA with poly(U)-containing (-) strand:RTC [double membrane vesicle viral factory outer membrane]
[Complex:R-HSA-9705682] MMP5:E pentamer [endoplasmic reticulum-Golgi intermediate compartment membrane]
[Complex:R-HSA-9770060] Spike trimer:ACE2 [plasma membrane]
[Complex:R-COV-9697195] di-antennary N-glycan-PALM-Spike trimer [endoplasmic reticulum-Golgi intermediate compartment]
[EntityWithAccessionedSequence:R-COV-9694459] 14-sugar N-glycan unfolded Spike [endoplasmic reticulum lumen]
[EntityWithAccessionedSequence:R-COV-9694465] Ub-3xPalmC-E [endoplasmic reticulum membrane]
[Complex:R-COV-9754744] SARS-CoV-2 gRNA:RTC: 5'-poly(U) RNA minus strand [double membrane vesicle viral factory outer membrane]
[Complex:R-HSA-9730518] STING:3CLpro dimer [cytosol]
[Complex:R-HSA-9729443] STAT1,STAT2:N [cytosol]
[EntityWithAccessionedSequence:R-COV-9756489] SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol]
[EntityWithAccessionedSequence:R-COV-9754741] SARS-CoV-2 nascent genomic 5'-poly(U)-RNA complement (minus strand) [cytosol]
[EntityWithAccessionedSequence:R-COV-9694387] O-glycosyl 3a [extracellular region]
[Complex:R-COV-9796421] S1:S2 trimer [plasma membrane]
[EntityWithAccessionedSequence:R-COV-9705293] 6 [endoplasmic reticulum-Golgi intermediate compartment membrane]
[Complex:R-COV-9754740] SARS-CoV-2 5'-poly(U)-gRNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane]
[Complex:R-HSA-9730525] STING:O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane]
[Complex:R-COV-9696901] high-mannose N-glycan-PALM-Spike trimer [endoplasmic reticulum-Golgi intermediate compartment]
[Complex:R-COV-9694787] Ub-3xPalmC-E pentamer [endoplasmic reticulum membrane]
[EntityWithAccessionedSequence:R-COV-9769950] S1 [plasma membrane]
[Complex:R-HSA-9754656] TJP1:E pentamer [endoplasmic reticulum-Golgi intermediate compartment membrane]
[Complex:R-HSA-9730482] U2 snRNA:nsp16 [nucleoplasm]
[Complex:R-HSA-9694258] nsp15:RB1 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694433] O-glycosyl 3a [plasma membrane]
[Complex:R-COV-9694457] O-glycosyl 3a tetramer [extracellular region]
[Complex:R-HSA-9705087] TBK1:pp1ab-nsp13 [cytosol]
[Complex:R-HSA-9754517] CAV1:3a [endoplasmic reticulum-Golgi intermediate compartment membrane]
[Complex:R-COV-9733504] Spike trimer [plasma membrane]
[Complex:R-COV-9756485] SUMO1-K62,ADPr-,p-11S,2T,met-2R,Ac-K375-N dimer [cytosol]
[Complex:R-HSA-9755714] M:MAVS [endoplasmic reticulum membrane]
[Complex:R-HSA-9694398] nsp16:VHL [cytosol]
[EntityWithAccessionedSequence:R-COV-9696920] di-antennary N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment]
[EntityWithAccessionedSequence:R-COV-9694796] nascent Spike [endoplasmic reticulum lumen]
[Complex:R-HSA-9754785] TUFM:M [endoplasmic reticulum membrane]
[EntityWithAccessionedSequence:R-COV-9694312] nascent E [endoplasmic reticulum lumen]
[EntityWithAccessionedSequence:R-COV-9694356] N [plasma membrane]
[Complex:R-COV-9694659] N dimer [nucleolus]
[Complex:R-HSA-9755322] 8:class I MHC:BECN1 complex [endoplasmic reticulum membrane]
[EntityWithAccessionedSequence:R-COV-9727295] 6 [endoplasmic reticulum membrane]
[EntityWithAccessionedSequence:R-COV-9727283] 8 [endoplasmic reticulum lumen]
[Complex:R-HSA-9705285] KPNA2:6 [endoplasmic reticulum-Golgi intermediate compartment membrane]
[Complex:R-HSA-9729513] G3BP1,G3BP2:N [cytosol]
[Complex:R-HSA-9694692] nsp13:DDX5 [cytosol]
[Complex:R-COV-9735243] nsp9 homodimer [cytosol]
[EntityWithAccessionedSequence:R-COV-9694754] N-glycan E [endoplasmic reticulum lumen]
[Complex:R-COV-9727285] 9b homodimer [cytosol]
[GenomeEncodedEntity:R-COV-9754729] SARS-CoV-2 GU-rich ssRNA [endosome lumen]
[Complex:R-HSA-9754533] HOPS:3a [endolysosome membrane]
[Complex:R-HSA-9755340] 8:antigen peptide bound class I MHC [lumenal side of endoplasmic reticulum membrane]
[DefinedSet:R-COV-9759710] SARS-CoV-2 G-rich RNA:RTC [double membrane vesicle viral factory outer membrane]
[Complex:R-HSA-9758533] N:MBL2 dodecamer:MASP1 dimer:MASP2-1 dimer [extracellular region]
[EntityWithAccessionedSequence:R-COV-9729325] SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane]
[EntityWithAccessionedSequence:R-COV-9696875] high-mannose N-glycan unfolded Spike [endoplasmic reticulum lumen]
[DefinedSet:R-NUL-9684904] TLR7, TLR8 ligands [endosome lumen]
[EntityWithAccessionedSequence:R-COV-9733472] fully glycosylated Spike [plasma membrane]
[Complex:R-HSA-9730486] U1 snRNA:nsp16 [nucleoplasm]
[Complex:R-HSA-9755729] N:MAVS [cytosol]
[EntityWithAccessionedSequence:R-COV-9730487] pp1ab-nsp16 [nucleoplasm]
[DefinedSet:R-COV-9694383] nsp9 [cytosol]
[EntityWithAccessionedSequence:R-COV-9694649] 9b [cytosol]
[EntityWithAccessionedSequence:R-COV-9766369] high-mannose N-glycan folded Spike [endoplasmic reticulum-Golgi intermediate compartment]
[Complex:R-HSA-9705026] TBK1:pp1ab-nsp6 [double membrane vesicle viral factory outer membrane]
[EntityWithAccessionedSequence:R-COV-9709803] 9b [mitochondrial outer membrane]
[Complex:R-HSA-9729447] TRIM25:N [cytosol]
[Complex:R-HSA-9755946] MAP1LC3B:TUFM:M [endoplasmic reticulum-Golgi intermediate compartment membrane]
[Complex:R-COV-9694286] nsp9 tetramer [cytosol]
[EntityWithAccessionedSequence:R-COV-9755945] 7a [endolysosome membrane]
[Complex:R-COV-9755345] 8 homodimer [endoplasmic reticulum lumen]
[Complex:R-HSA-9729509] 14-3-3 dimer:N [cytosol]
[Complex:R-COV-9697194] tri-antennary N-glycan-PALM-Spike trimer [endoplasmic reticulum-Golgi intermediate compartment]
[EntityWithAccessionedSequence:R-COV-9731277] pp1ab-nsp6 [nuclear envelope]
[Complex:R-HSA-9733494] S1 trimer:ACE2:S2 trimer [plasma membrane]
[EntityWithAccessionedSequence:R-COV-9770188] S(686-815) [plasma membrane]
[Complex:R-COV-9815359] ExoN inhibitors:nsp10:nsp14 [cytosol]
[Complex:R-COV-9694359] SARS coronavirus gRNA with secondary structure:RTC:nascent RNA minus strand [double membrane vesicle viral factory outer membrane]
[DefinedSet:R-COV-9731255] nsp6 [nuclear envelope]
[Complex:R-HSA-9770062] S1:ACE2 [plasma membrane]
[DefinedSet:R-ALL-9731679] ExoN inhibitors [cytosol]
[EntityWithAccessionedSequence:R-COV-9770189] Spike S2' Fragment [plasma membrane]
[Complex:R-COV-9733017] nsp3:PLpro inhibitors [cytosol]
[Complex:R-HSA-9698376] ZCRB1:m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol]
[EntityWithAccessionedSequence:R-COV-9731276] pp1a-nsp6 [nuclear envelope]
[BlackBoxEvent:R-HSA-9694733] Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand)
[BlackBoxEvent:R-HSA-9694549] RTC completes synthesis of the minus strand genomic RNA complement
[BlackBoxEvent:R-HSA-9694605] nsp12 synthesizes minus strand SARS-CoV-2 genomic RNA complement
[Reaction:R-HSA-9694438] GalNAc is transferred onto 3a
[Reaction:R-HSA-9694521] nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand)
[Reaction:R-HSA-9694718] O-glycosylation of 3a is terminated
[BlackBoxEvent:R-HSA-9694344] Synthesis of SARS-CoV-2 minus strand subgenomic mRNAs by template switching
[BlackBoxEvent:R-HSA-9694471] Polyadenylation of SARS-CoV-2 genomic RNA (plus strand)
[BlackBoxEvent:R-HSA-9694392] 3a translocates to the ERGIC
[Reaction:R-HSA-9694338] nsp1-4 cleaves itself
[Reaction:R-HSA-9694633] SARS virus buds into ERGIC lumen
[Reaction:R-HSA-9694539] nsp15 binds nsp8
[Reaction:R-HSA-9694436] nsp15 forms a hexamer
[Reaction:R-HSA-9729260] GSK3 phosphorylates nucleoprotein
[Reaction:R-HSA-9694441] 3CLp cleaves pp1a
[Reaction:R-HSA-9729841] SARS-CoV-2 nsp8 binds to 7SL RNA
[BlackBoxEvent:R-HSA-9694476] nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs
[Reaction:R-HSA-9694454] Replication transcription complex binds SARS-CoV-2 genomic RNA
[BlackBoxEvent:R-HSA-9694331] nsp3-4 is glycosylated
[BlackBoxEvent:R-HSA-9694506] Synthesis of SARS-CoV-2 plus strand subgenomic mRNAs
[Reaction:R-HSA-9694579] Spike glycoprotein of SARS-CoV-2 binds ACE2 on host cell
[BlackBoxEvent:R-HSA-9694567] pp1a forms a dimer
[Reaction:R-HSA-9694377] pp1a cleaves itself
[Reaction:R-HSA-9729279] Nucleoprotein is ADP-ribosylated
[BlackBoxEvent:R-HSA-9694737] nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA (plus strand)
[BlackBoxEvent:R-HSA-9694370] mRNA9a is translated to Nucleoprotein
[BlackBoxEvent:R-HSA-9694581] RTC synthesizes SARS-CoV-2 plus strand genomic RNA
[Reaction:R-HSA-9694641] Viral release
[Reaction:R-HSA-9694732] 3CLp cleaves pp1ab
[Reaction:R-HSA-9694721] nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA (plus strand)
[BlackBoxEvent:R-HSA-9694274] mRNA1 is translated to pp1ab
[BlackBoxEvent:R-HSA-9698988] Direct Host Cell Membrane Membrane Fusion and Release of SARS-CoV-2 Nucleocapsid
[BlackBoxEvent:R-HSA-9694611] nsp4 is glycosylated
[Reaction:R-HSA-9729307] Nucleoprotein is SUMOylated
[Reaction:R-HSA-9694551] 3CLp cleaves nsp6-11
[BlackBoxEvent:R-HSA-9694389] nsp3 is glycosylated
[Reaction:R-HSA-9694723] Uncoating of SARS-CoV-2 Genome
[Reaction:R-HSA-9694601] nsp3-4 cleaves itself
[BlackBoxEvent:R-HSA-9694317] Nsp3, nsp4, and nsp6 produce replicative organelles
[BlackBoxEvent:R-HSA-9694794] mRNA3 is translated to protein 3a
[Reaction:R-HSA-9694495] RTC binds SARS-CoV-2 genomic RNA complement (minus strand)
[Reaction:R-HSA-9694333] 3CLp forms a homodimer
[Reaction:R-HSA-9694499] nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs
[Reaction:R-HSA-9694625] nsp3 cleaves nsp1-4
[Reaction:R-HSA-9729330] SRPK1/2 phosphorylates nucleoprotein
[Reaction:R-HSA-9694689] Fusion and Release of SARS-CoV-2 Nucleocapsid
[BlackBoxEvent:R-HSA-9694576] nsp3 binds to nsp7-8 and nsp12-16
[Reaction:R-HSA-9694528] Accessory proteins are recruited to the maturing virion
[Reaction:R-HSA-9729318] CSNK1A1 phosphorylates nucleoprotein
[Reaction:R-HSA-9694662] Protein 3a forms a homotetramer
[Reaction:R-HSA-9694363] Dimerisation of nucleoprotein
[BlackBoxEvent:R-HSA-9694334] mRNA1 is translated to pp1a
[Reaction:R-HSA-9694632] nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA
[BlackBoxEvent:R-HSA-9694492] nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand)
[BlackBoxEvent:R-HSA-9694265] nsp13 helicase melts secondary structures in SARS-CoV-2 genomic RNA template
[BlackBoxEvent:R-HSA-9694630] Nsp3:nsp4 binds to nsp6
[Reaction:R-HSA-9815529] nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs
[BlackBoxEvent:R-HSA-9694277] nsp8 generates RNA primers
[Reaction:R-HSA-9694524] nsp13 binds nsp12
[Reaction:R-HSA-9694661] TMPRSS2 Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis
[Reaction:R-HSA-9729283] Nucleoprotein is methylated by PRMT1
[Reaction:R-HSA-9729300] Unknown kinase phosphorylates nucleoprotein
[Reaction:R-HSA-9694455] SUMO-p-N protein dimer binds genomic RNA
[Reaction:R-HSA-9756574] SARS-CoV-2 S binds SFTPD 12mer
[Reaction:R-HSA-9756494] CREBBP acetylates SARS-CoV-2 N at K375
[BlackBoxEvent:R-HSA-9694294] E pentamer is transported to the Golgi
[Reaction:R-HSA-9729500] SARS-CoV-2 N binds to 14-3-3 proteins
[Pathway:R-HSA-9705671] SARS-CoV-2 activates/modulates innate and adaptive immune responses
[Pathway:R-HSA-9755779] SARS-CoV-2 targets host intracellular signalling and regulatory pathways
[BlackBoxEvent:R-HSA-9727303] mRNA9 is translated to protein 9b
[Reaction:R-HSA-9694542] nsp14 binds nsp10
[Reaction:R-HSA-9717658] SARS-CoV-2 N binds DDX58
[Reaction:R-HSA-9705082] SARS-CoV-2 nsp13 binds TBK1
[Reaction:R-HSA-9729741] SARS-CoV-2 3CLpro dimer cleaves NLRP12
[Reaction:R-HSA-9705010] SARS-CoV-2 nsp6 binds TBK1
[Pathway:R-HSA-9705677] SARS-CoV-2 targets PDZ proteins in cell-cell junction
[Reaction:R-HSA-9705299] SARS-CoV-2 6 binds KPNA2
[BlackBoxEvent:R-HSA-9694280] mRNA4 is translated to protein E
[Reaction:R-HSA-9729849] SARS-CoV-2 nsp1 binds to 40S ribosomal complex
[BlackBoxEvent:R-HSA-9727300] 9b homodimer localizes to the mitochondrial outer membrane
[Reaction:R-HSA-9691335] nsp7 binds nsp8
[Reaction:R-HSA-9755359] SARS-CoV-2 8:class I MHC binds BECN1
[BlackBoxEvent:R-HSA-9697018] Addition of sialic acids on some Spike glycosyl sidechains
[Reaction:R-HSA-9694452] Protein E forms a homopentamer
[BlackBoxEvent:R-HSA-9727292] mRNA6 is translated to protein 6
[Reaction:R-HSA-9694341] Spike protein gets palmitoylated
[Reaction:R-HSA-9730521] SARS-CoV-2 3a induces potassium efflux
[Reaction:R-HSA-9754644] SARS-CoV-2 E pentamer binds TJP1
[BlackBoxEvent:R-HSA-9694568] Nucleoprotein translocates to the ERGIC outer membrane
[BlackBoxEvent:R-HSA-9727284] 9b forms a homodimer
[Reaction:R-HSA-9729730] SARS-CoV-2 nsp3 cleaves IRF3
[BlackBoxEvent:R-HSA-9727305] mRNA8 is translated to protein 8
[Reaction:R-HSA-9694287] Cleavage of S protein into S1:S2
[BlackBoxEvent:R-HSA-9727293] 6 localizes to the nuclear envelope
[Reaction:R-HSA-9729481] SARS-CoV-2 N binds to G3BP1,G3BP2
[Pathway:R-HSA-9754560] SARS-CoV-2 modulates autophagy
[Reaction:R-HSA-9756470] N binds to heme
[Reaction:R-HSA-9754839] SARS-CoV-2 9b binds IKBKG
[Reaction:R-HSA-9755413] SARS-CoV-2 8 binds IL17RA
[BlackBoxEvent:R-HSA-9694681] mRNA5 is translated to protein M
[Reaction:R-HSA-9694445] nsp16 binds nsp10
[Reaction:R-HSA-9765952] nsp12 guanylates nsp7
[Reaction:R-HSA-9694337] Trimmed spike protein binds to calnexin
[Reaction:R-HSA-9697423] Endocytosis of SARS-CoV-2 Virion
[BlackBoxEvent:R-HSA-9694447] mRNA2 is translated to Spike
[BlackBoxEvent:R-HSA-9694364] N-glycan glucose trimming of Spike
[Reaction:R-HSA-9755354] 8 forms a homodimer
[Reaction:R-HSA-9755777] SARS-CoV-2 M, N bind to PDPK1
[Reaction:R-HSA-9730501] SARS-CoV-2 3CLpro dimer binds to STING
[Reaction:R-HSA-9729437] SARS-CoV-2 N binds to TRIM25
[Reaction:R-HSA-9758529] SARS-CoV-2 N binds MASP2
[Pathway:R-HSA-9754678] SARS-CoV-2 modulates host translation machinery
[BlackBoxEvent:R-HSA-9694529] Ubiquination of protein E
[BlackBoxEvent:R-HSA-9754763] SARS-CoV-2 M protein binds TUFM
[Reaction:R-HSA-9754537] SARS-CoV-2 3a tetramer binds to VPS39 within HOPS complex
[Reaction:R-HSA-9699007] FURIN Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis
[BlackBoxEvent:R-HSA-9694308] 3a is externalized together with membrane structures
[BlackBoxEvent:R-HSA-9754775] SARS-CoV-2 M protein binds MAP1LC3B
[BlackBoxEvent:R-HSA-9694656] Spike trimer glycoside chains are extended
[Reaction:R-HSA-9691363] nsp12 binds nsp7 and nsp8
[Reaction:R-HSA-9694401] E protein gets palmitoylated
[Reaction:R-HSA-9729704] SARS-CoV-2 3CLpro dimer cleaves TAB1
[Reaction:R-HSA-9730505] SARS-CoV-2 3a binds to UVRAG
[Reaction:R-HSA-9754616] SARS-CoV-2 E pentamer transports Ca2+
[BlackBoxEvent:R-HSA-9694525] M protein gets N-glycosylated
[Reaction:R-HSA-9694444] E and N are recruited to the M lattice
[BlackBoxEvent:R-HSA-9754827] SARS-CoV-2 M binds TBK1
[Reaction:R-HSA-9694553] Recruitment of Spike trimer to assembling virion
[BlackBoxEvent:R-HSA-9698333] Spike trimer moves into the ERGIC membrane
[BlackBoxEvent:R-HSA-9696980] Spike trimer glycoside chains get additional branches
[Reaction:R-HSA-9757097] SARS-CoV-2 N binds NLRP3
[Pathway:R-HSA-9705683] SARS-CoV-2-host interactions
[Reaction:R-HSA-9755734] SARS-CoV-2 N binds IKBKB
[BlackBoxEvent:R-HSA-9771686] nsp12 acquires Fe-S cluster cofactors
[Reaction:R-HSA-9709663] SARS-CoV-2 9b binds TOMM70
[BlackBoxEvent:R-HSA-9696807] N-glycan mannose trimming of Spike
[Reaction:R-HSA-9730488] SARS-CoV-2 nsp16 binds to U2 snRNA
[Reaction:R-HSA-9730528] SARS-CoV-2 3a binds to STING
[Reaction:R-HSA-9708889] SARS-CoV-2 6 binds NUP98:RAE1 within NPC
[Reaction:R-HSA-9694281] Encapsidation of SARS coronavirus genomic RNA
[Reaction:R-HSA-9755328] SARS-CoV-2 8 binds class I MHC
[BlackBoxEvent:R-HSA-9694572] 3a localizes to the cell membrane
[BlackBoxEvent:R-HSA-9727297] mRNA7 is translated to protein 7a
[Reaction:R-HSA-9705681] MPP5 binds SARS-CoV-2 E pentamer
[BlackBoxEvent:R-HSA-9694793] Spike protein gets N-glycosylated
[Reaction:R-HSA-9729835] SARS-CoV-2 nsp9 binds to 7SL RNA
[Reaction:R-HSA-9729725] SARS-CoV-2 nsp3 deISGylates ISGylated IRF3
[Reaction:R-HSA-9755757] SARS-CoV-2 N binds TAK1
[BlackBoxEvent:R-HSA-9754554] SARS-COV 7a translocates to the late endosome membrane
[BlackBoxEvent:R-HSA-9694555] Protein M localizes to the Golgi membrane
[BlackBoxEvent:R-HSA-9716160] SARS-CoV-2 M protein binds MAVS
[Reaction:R-HSA-9730483] SARS-CoV-2 nsp16 binds to U1 snRNA
[Reaction:R-HSA-9694467] Spike protein forms a homotrimer
[Reaction:R-HSA-9729454] SARS-CoV-2 N protein binds STAT1, STAT2
[BlackBoxEvent:R-HSA-9694367] Glycosylated M localizes to the Golgi membrane
[Reaction:R-HSA-9755244] SARS-CoV-2 nsp3 deISGylates ISGylated IFIH1
[Reaction:R-HSA-9694487] M protein oligomerization
[BlackBoxEvent:R-HSA-9694780] Spike translocates to ERGIC
[Reaction:R-HSA-9754518] SARS-CoV-2 3a tetramer binds to CAV1
[Reaction:R-HSA-9755747] SARS-CoV-2 N binds MAVS
[BlackBoxEvent:R-HSA-9727288] 7a localizes to the ERGIC membrane
[Pathway:R-HSA-9772572] Early SARS-CoV-2 Infection Events
[BlackBoxEvent:R-HSA-9694592] 3CLp dimer binds 3CLp inhibitors
[BlackBoxEvent:R-HSA-9694575] Nucleoprotein translocates to the plasma membrane
[Reaction:R-HSA-9769949] FURIN Mediated SARS-CoV-2 Spike Protein Cleavage
[Pathway:R-HSA-9694516] SARS-CoV-2 Infection
[BlackBoxEvent:R-HSA-9694790] E protein gets N-glycosylated
[Pathway:R-HSA-9694631] Maturation of nucleoprotein
[Reaction:R-HSA-9694419] SARS-CoV-2 gRNA complement (minus strand):RTC binds RTC inhibitors
[BlackBoxEvent:R-HSA-9694580] nsp8 binds MAP1LC3B
[Pathway:R-HSA-9694301] Maturation of replicase proteins
[BlackBoxEvent:R-HSA-9769812] Spike Trimer Translocates to the Plasma Membrane
[BlackBoxEvent:R-HSA-9694727] Endocytosis of protein 3a
[Reaction:R-HSA-9732822] nsp3 binds to PLpro inhibitors
[Reaction:R-HSA-9694677] ZCRB1 binds 5'UTR of SARS-CoV-2 genomic RNA
[Reaction:R-HSA-9707827] Spike binds Spike inhibitors
[BlackBoxEvent:R-HSA-9694345] Nucleoprotein translocates to the nucleolus
[BlackBoxEvent:R-HSA-9694792] nsp12 misincorporates a nucleotide in nascent RNA minus strand
[Reaction:R-HSA-9694390] nsp15 binds RB1
[Pathway:R-HSA-9694682] SARS-CoV-2 Genome Replication and Transcription
[Pathway:R-HSA-9694493] Maturation of protein E
[Reaction:R-HSA-9731708] nsp10:nsp14 binds to ExoN inhibitors
[Pathway:R-HSA-9694719] Maturation of protein 3a
[Pathway:R-HSA-9694676] Translation of Replicase and Assembly of the Replication Transcription Complex
[Pathway:R-HSA-9733458] Induction of Cell-Cell Fusion
[Reaction:R-HSA-9694541] SARS-CoV-2 gRNA:RTC:RNA primer binds RTC inhibitors
[Reaction:R-HSA-9694665] SARS-CoV-2 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors
[Pathway:R-HSA-9694322] Virion Assembly and Release
[Pathway:R-HSA-9694686] Replication of the SARS-CoV-2 genome
[BlackBoxEvent:R-HSA-9755252] nsp15 cleaves viral poly(U)-RNA
[Reaction:R-HSA-9694406] nsp13 binds DDX5
[Pathway:R-HSA-9694548] Maturation of spike protein
[Pathway:R-HSA-9694635] Translation of Structural Proteins
[Reaction:R-HSA-9694520] nsp16 binds VHL
[BlackBoxEvent:R-HSA-9770063] S1,S2 Dissociate from S1:ACE2:S2
[Pathway:R-HSA-9694786] Transcription of SARS-CoV-2 sgRNAs
[BlackBoxEvent:R-HSA-9694261] nsp9 forms a homotetramer
[Reaction:R-HSA-9758486] Unknown kinase phosphorylates 9b
[BlackBoxEvent:R-HSA-9694373] Unphosphorylated nucleoprotein translocates to the plasma membrane
[Pathway:R-HSA-9694271] Assembly of the SARS-CoV-2 Replication-Transcription Complex (RTC)
[Reaction:R-HSA-9770187] S2 Cleavage by TMPRSS2 Exposes S2' Initiating Cell-Cell Fusion
[Pathway:R-HSA-9694614] Attachment and Entry
[Pathway:R-HSA-9727281] Translation of Accessory Proteins
[BlackBoxEvent:R-HSA-9731262] nsp6 localizes to the nuclear envelope
[Pathway:R-HSA-9772573] Late SARS-CoV-2 Infection Events
[BlackBoxEvent:R-HSA-9731274] nsp16 localizes to the nucleus
[BlackBoxEvent:R-HSA-9698265] Enhanced autophagosome formation
[Reaction:R-HSA-9733495] Viral Spike Binds to ACE2 on Uninfected Cell
[Pathway:R-HSA-9694594] Maturation of protein M
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