MYH13
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Protein-coding gene in the species Homo sapiens
| MYH13 | |||||||||||||||||||||||||||||||||||||||||||||||
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| Aliases | MYH13 , MyHC-IIL, MyHC-eo, myosin, heavy chain 13, skeletal muscle, myosin heavy chain 13 | ||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 603487; MGI: 1339967; HomoloGene: 55780; GeneCards: MYH13; OMA:MYH13 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||
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Myosin-13 also known as myosin, heavy chain 13 is a protein which in humans is encoded by the MYH13 gene.[5] [6]
Function
[edit ]MYH13 is a myosin whose expression is restricted primarily to the extrinsic eye muscles which are specialized for function in eye movement.[5]
References
[edit ]- ^ a b c GRCh38: Ensembl release 89: ENSG00000006788 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000060180 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ a b Winters LM, Briggs MM, Schachat F (November 1998). "The human extraocular muscle myosin heavy chain gene (MYH13) maps to the cluster of fast and developmental myosin genes on chromosome 17". Genomics. 54 (1): 188–9. doi:10.1006/geno.1998.5558. PMID 9806854.
- ^ Weiss A, Schiaffino S, Leinwand LA (July 1999). "Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity". J. Mol. Biol. 290 (1): 61–75. doi:10.1006/jmbi.1999.2865. PMID 10388558.
Further reading
[edit ]- Weiss A, McDonough D, Wertman B, et al. (1999). "Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved". Proc. Natl. Acad. Sci. U.S.A. 96 (6): 2958–63. Bibcode:1999PNAS...96.2958W. doi:10.1073/pnas.96.6.2958 . PMC 15877 . PMID 10077619.
- Schachat F, Briggs MM (2002). "Phylogenetic implications of the superfast myosin in extraocular muscles". J. Exp. Biol. 205 (Pt 15): 2189–201. doi:10.1242/jeb.205.15.2189. PMID 12110653.
- Trynka G, Zhernakova A, Romanos J, et al. (2009). "Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling". Gut. 58 (8): 1078–83. doi:10.1136/gut.2008.169052. PMID 19240061. S2CID 17111427.
- Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147 . PMID 15231747.
- Schjeide BM, McQueen MB, Mullin K, et al. (2009). "Assessment of Alzheimer's disease case-control associations using family-based methods". Neurogenetics. 10 (1): 19–25. doi:10.1007/s10048-008-0151-3. PMC 2841132 . PMID 18830724.
- Shoeman RL, Sachse C, Höner B, et al. (1993). "Cleavage of human and mouse cytoskeletal and sarcomeric proteins by human immunodeficiency virus type 1 protease. Actin, desmin, myosin, and tropomyosin". Am. J. Pathol. 142 (1): 221–30. PMC 1886840 . PMID 8424456.
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