KRT79

Identifiers

KRT79 , K6L, KRT6L, keratin 79

External IDs

OMIM: 611160; MGI: 2385030; HomoloGene: 89169; GeneCards: KRT79; OMA:KRT79 - orthologs

Gene location (Human)
Chromosome 12 (human)
Chr.	Chromosome 12 (human) ^[1]
Chromosome 12 (human) Genomic location for KRT79 Genomic location for KRT79
Band	12q13.13	Start	52,821,408 bp ^[1]
Band	12q13.13	End	52,834,311 bp ^[1]

Gene location (Mouse)
Chromosome 15 (mouse)
Chr.	Chromosome 15 (mouse)^[2]
Chromosome 15 (mouse) Genomic location for KRT79 Genomic location for KRT79
Band	15\|15 F2	Start	101,837,767 bp ^[2]
Band	15\|15 F2	End	101,848,759 bp ^[2]

RNA expression pattern

Bgee

Human	Mouse (ortholog)
Top expressed in skin of thigh vulva skin of abdomen nipple subcutaneous adipose tissue mammary gland lactiferous gland upper lobe of left lung right lung islet of Langerhans	Top expressed in lip skin of external ear skin of back right lung lobe mucous cell of stomach skin of abdomen sexually immature organism epidermis conjunctival fornix embryo
More reference expression data

BioGPS

n/a

Gene ontology
Molecular function	enzyme binding protein binding structural molecule activity
Cellular component	keratin filament extracellular exosome intermediate filament cytosol
Biological process	keratinization cornification
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


338785


223917

Ensembl


ENSG00000185640


ENSMUSG00000061397

UniProt


Q5XKE5


Q8VED5

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 12: 52.82 – 52.83 Mb

Chr 15: 101.84 – 101.85 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human View/Edit Mouse

Keratin 79 also known as KRT79 is a protein which humans is encoded by the KRT79 gene.^[5]^[6]

Function

[edit ]

Keratins, such as KRT79, are filament proteins that make up one of the major structural fibers of epithelial cells ^[7]

References

[edit ]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000185640 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000061397 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Hesse M, Magin TM, Weber K (July 2001). "Genes for intermediate filament proteins and the draft sequence of the human genome: novel keratin genes and a surprisingly high number of pseudogenes related to keratin genes 8 and 18". J. Cell Sci. 114 (Pt 14): 2569–75. doi:10.1242/jcs.114.14.2569. PMID 11683385.
^ "Entrez Gene: KRT79 keratin 79".
^ Rogers MA, Edler L, Winter H, Langbein L, Beckmann I, Schweizer J (March 2005). "Characterization of new members of the human type II keratin gene family and a general evaluation of the keratin gene domain on chromosome 12q13.13". J. Invest. Dermatol. 124 (3): 536–44. doi:10.1111/j.0022-202X.2004.23530.x . PMID 15737194.

Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Sowa ME, Bennett EJ, Gygi SP, Harper JW (2009). "Defining the human deubiquitinating enzyme interaction landscape". Cell. 138 (2): 389–403. doi:10.1016/j.cell.2009年04月04日2. PMC 2716422 . PMID 19615732.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

v
t
e

Proteins of the cytoskeleton

Human

Microfilaments
and ABPs

Myofilament

Actins	A1 A2 B C1 G1 G2
Myosins	I MYO1A MYO1B MYO1C MYO1D MYO1E MYO1F MYO1G MYO1H) II MYH1 MYH2 MYH3 MYH4 MYH6 MYH7 MYH7B MYH8 MYH9 MYH10 MYH11 MYH13 MYH14 MYH15 MYH16 III MYO3A MYO3B V MYO5A MYO5B MYO5C VI MYO6 VII MYO7A MYO7B IX MYO9A MYO9B X MYO10 XV MYO15A XVIII MYO18A MYO18B LC MYL1 MYL2 MYL3 MYL4 MYL5 MYL6 MYL6B MYL7 MYL9 MYLIP MYLK MYLK2 MYLL1
Other	Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors Cofilin 1 2 Destrin Gelsolin Profilin 1 2 Titin

Other

Intermediate
filaments

Type 1/2
(Keratin,
Cytokeratin)

Epithelial keratins (soft alpha-keratins)	type I/chromosome 17 9 10 12 13 14 15 16 17 19 20 chromosome 12 18 none 21 type II/chromosome 12 1 2A 3 4 5 6A 6B 6C 7 8
Hair keratins (hard alpha-keratins)	type I/chromosome 17 31 32 33A 33B 34 35 36 37 38 type II/chromosome 12 81 82 83 84 85 86
Ungrouped alpha	chromosome 17 23 24 25 26 27 28 39 40 chromosome 12 71 72 73 74 75 76 77 78 79 80
Not alpha	Beta-keratin

Type 3

Type 4

Type 5

Microtubules
and MAPs

Tubulins	TUBA1A TUBA1B TUBA1C TUBA3C TUBA3D TUBA3E TUBA4A TUBA8 TUBB TUBB1 TUBB2A TUBB2B TUBB2C TUBB3 TUBB4 TUBB4Q TUBB6 TUBB8 TUBG1 TUBG2 TUBGCP2 TUBGCP3 TUBGCP4 TUBGCP5 TUBGCP6 TUBD1 TUBE1
MAPs	EB1 EB2 EB3 MAP1A MAP1B MAP2 MAP4
Kinesins	KIF1A KIF1B KIF2A KIF2C KIF3B KIF3C KIF4A KIF4B KIF5A KIF5B KIF5C KIF6 KIF7 KIF9 KIF11 KIF12 KIF13A KIF13B KIF14 KIF15 KIF16B KIF17 KIF18A KIF18B KIF19 KIF20A KIF20B KIF21A KIF21B KIF22 KIF23 KIF24 KIF25 KIF26A KIF26B KIF27 KIFC1 KIFC2 KIFC3
Dyneins	axonemal: DNAH1 DNAH2 DNAH3 DNAH5 DNAH6 DNAH7 DNAH8 DNAH9 DNAH10 DNAH11 DNAH12 DNAH13 DNAH14 DNAH17 DNAI1 DNAI2 DNALI1 DNAL1 DNAL4 cytoplasmic: DYNC1H1 DYNC2H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNC2LI1 DYNLL1 DYNLL2 DYNLRB1 DYNLRB2 DYNLT1 DYNLT3
Microtubule organising proteins	CAMSAP1 CAMSAP2 CAMSAP3 Centrin 1 Centrin 2 Centrin 3 PCM1
Microtubule severing proteins	Katanin Spastin
Other	Tau protein Dynactin DCTN1 Stathmin Tektin TEKT1 TEKT2 TEKT3 TEKT4 TEKT5 Dynamin DNM1 DNM2 DNM3