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KRT36

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
KRT36
Identifiers
Aliases KRT36 , HA6, KRTHA6, hHa6, keratin 36
External IDsOMIM: 604540; MGI: 109364; HomoloGene: 88459; GeneCards: KRT36; OMA:KRT36 - orthologs
Gene location (Human)
Chromosome 17 (human)
Chr. Chromosome 17 (human) [1]
Band 17q21.2Start41,486,136 bp [1]
End41,492,546 bp [1]
Gene location (Mouse)
Chromosome 11 (mouse)
Chr. Chromosome 11 (mouse)[2]
Band 11|11 DStart99,992,833 bp [2]
End99,996,452 bp [2]
RNA expression pattern
Bgee
Human Mouse (ortholog)
  • testicle

  • body of tongue

  • superior surface of tongue

  • mucosa of esophagus

  • spleen

  • cervix

  • lymph node

  • skin of limb

  • skin of leg

  • granulocyte
  • lip

  • hair follicle

  • embryo

  • skin of external ear

  • skin of back

  • tongue

  • filiform papilla

  • skin of abdomen

  • mammary gland

  • oocyte
More reference expression data
BioGPS
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

8689

16673

Ensembl

ENSG00000126337

ENSMUSG00000020916

UniProt

O76013

B1AQ75

RefSeq (mRNA)

NM_003771

NM_001174099
NM_008472

RefSeq (protein)

NP_003762

NP_001167570

Location (UCSC)Chr 17: 41.49 – 41.49 Mb Chr 11: 99.99 – 100 Mb
PubMed search[3] [4]
Wikidata

Keratin, type I cuticular Ha6 is a protein that in humans is encoded by the KRT36 gene.[5] [6] [7]

The protein encoded by this gene is a member of the keratin gene family. This type I hair keratin is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q21.2 and have the same direction of transcription.[7]

References

[edit ]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000126337Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020916Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Rogers MA, Winter H, Wolf C, Heck M, Schweizer J (Nov 1998). "Characterization of a 190-kilobase pair domain of human type I hair keratin genes". J Biol Chem. 273 (41): 26683–91. doi:10.1074/jbc.273.41.26683 . PMID 9756910.
  6. ^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (Jul 2006). "New consensus nomenclature for mammalian keratins". J Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177 . PMID 16831889.
  7. ^ a b "Entrez Gene: KRT36 keratin 36".

Further reading

[edit ]
Human
Microfilaments
and ABPs
Myofilament
Actins
Myosins
Other
Other
Intermediate
filaments
Type 1/2
(Keratin,
Cytokeratin)
Epithelial keratins
(soft alpha-keratins)
Hair keratins
(hard alpha-keratins)
Ungrouped alpha
Not alpha
Type 3
Type 4
Type 5
Microtubules
and MAPs
Tubulins
MAPs
Kinesins
Dyneins
Microtubule organising proteins
Microtubule severing proteins
Other
Catenins
Membrane
Other
Nonhuman


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