2C-F
| Clinical data | |
|---|---|
| Other names | 4-Fluoro-2,5-dimethoxyphenethylamine; 2,5-Dimethoxy-4-fluorophenethylamine |
| Routes of administration | Oral [1] |
| Drug class | Serotonergic psychedelic; Hallucinogen |
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| Legal status | |
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| Pharmacokinetic data | |
| Onset of action | Unknown[1] |
| Duration of action | Unknown[1] |
| Identifiers | |
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| CompTox Dashboard (EPA) | |
| Chemical and physical data | |
| Formula | C10H14FNO2 |
| Molar mass | 199.225 g·mol−1 |
| 3D model (JSmol) | |
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2C-F, also known as 4-fluoro-2,5-dimethoxyphenethylamine, is a psychedelic drug of the phenethylamine and 2C families.[1] [2] It is taken orally.[1]
Use effects
[edit ]In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists the dose of 2C-F as greater than 250 mg orally and its duration as unknown.[1] At a dose of 250 mg, 2C-F produces slight and uncertain effects including possible modest closed-eye visuals and pleasant lethargy.[1]
Interactions
[edit ]Pharmacology
[edit ]Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-F.[1] [3]
Chemistry
[edit ]Properties
[edit ]2C-F may be found as a brownish freebase oil, or as a white crystalline hydrochloride salt.
Synthesis
[edit ]The chemical synthesis of 2C-F has been described.[1]
Analogues
[edit ]Analogues of 2C-F include 2C-B, 2C-I, 2C-C, DOF, and 25F-NBOMe, among others.[1]
History
[edit ]2C-F was first described in the literature by Alexander Shulgin in his 1991 book PiHKAL (Phenethylamines I Have Known and Loved).[1]
Society and culture
[edit ]Legal status
[edit ]Canada
[edit ]As of October 31, 2016, 2C-F is a controlled substance (Schedule III) in Canada.[4]
See also
[edit ]References
[edit ]- ^ a b c d e f g h i j k Shulgin A, Shulgin A (September 1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628. 2C-F Entry in PiHKAL
- ^ Shulgin A, Manning T, Daley P (2011). The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds . Vol. 1. Berkeley: Transform Press. ISBN 978-0-9630096-3-0.
- ^ Rudin D, Luethi D, Hoener MC, Liechti ME (2022). "Structure-activity Relation of Halogenated 2,5-Dimethoxyamphetamines Compared to their α‐Desmethyl (2C) Analogues". The FASEB Journal. 36 (S1). doi:10.1096/fasebj.2022.36.S1.R2121 . ISSN 0892-6638.
- ^ "Regulations Amending the Food and Drug Regulations (Part J — 2C-phenethylamines)". Controlled Drugs and Substances Act. 150 (9). Government of Canada. 4 May 2016.