C. albicans C3_02260C Summary

Last curated 2023年04月10日
See the Literature Guide for most recent publications.

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Summary
Locus History Literature Gene Ontology Phenotype Homologs Protein
C3_02260C BASIC INFORMATION [ View References ]
Systematic Name, Reference Strain C3_02260C_A (C. albicans SC5314)
Assembly 19/21 Identifier orf19.1619
Alias CTK11
orf19.9187, IPF25612.12 , IPF4233.22 , Contig4-2798_00163 , orf6.64534 , CA40142 , CaO19.16191 , CaO19.91871 , orf19.1619, C3_02260C_B, C3_02260C
Feature Type ORF, Verified
Description Putative kinase subunit of RNA polymerase II carboxy-terminal domain kinase I; possibly an essential gene, disruptants not obtained by UAU1 method (5)
Literature
Allele Name C3_02260C_B
Allelic Variation Non-synonymous variation between alleles
CUG Codons C3_02260C_A: 4
C3_02260C_B: 4
Systematic Names Used in Other Strains CAWG_02552 (C. albicans WO-1)
Orthologous genes in Candida species C. dubliniensis CD36 Ortholog(s) : Cd36_82230
C. parapsilosis CDC317 Ortholog(s) : CPAR2_405120
C. auris B8441 Ortholog(s) : B9J08_002634
C. glabrata CBS138 Ortholog(s) : CAGL0D02002g
View ortholog cluster : 19 genes among 19 Candida-related species/strains
Ortholog(s) in non-CGD species S. pombe (SPAC2F3.15) ; S. cerevisiae (CTK1)
Best hit(s) in non-CGD species A. nidulans (stk47) ; N. crassa (stk-47)
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GO Annotations View all C3_02260C GO evidence and references

Molecular Function
Manually curated * protein kinase activity (IMP)
Computational * ATP binding (IEA with EBI: Protein kinase, ATP binding site, EBI: Protein kinase domain)
* RNA polymerase II CTD heptapeptide repeat S2 kinase activity (IEA with S. pombe: SPAC2F3.15)
* RNA polymerase II CTD heptapeptide repeat kinase activity (IEA with S. pombe: SPAC2F3.15)
* protein kinase activity (IEA with EBI: Protein kinase domain, EBI: Serine/threonine-protein kinase, active site)

Biological Process
Manually curated * positive regulation of filamentous growth (IMP)
Computational * positive regulation of transcription by RNA polymerase II (IEA with S. pombe: SPAC2F3.15)
* protein phosphorylation (IEA with EBI: Protein kinase domain, EBI: Serine/threonine-protein kinase, active site)

Cellular Component
Computational * chromatin (IEA with S. pombe: SPAC2F3.15)
* nuclear cyclin-dependent protein kinase holoenzyme complex (IEA with S. pombe: SPAC2F3.15)
Mutant Phenotype View all C3_02260C Phenotype details and references
Large-scale survey
heterozygous null * viable

null * inviable

repressible * vegetative growth: normal rate
* viable

Sequence Information Ca22chr3A_C_albicans_SC5314:490833 to 489073 | JBrowse
Note: this feature is encoded on the Crick strand.
Last UpdateCoordinates: 2016年06月22日 | Sequence: 2016年06月22日

Subfeature Details
Relative
Coordinates		Chromosomal
Coordinates		Most Recent Update
CoordinatesSequence
CDS 1to1761490,833to489,0732016年06月22日2016年06月22日

Retrieve Sequences
Sequence Analysis Tools
Maps & Displays
Sequence Information Ca22chr3A_C_albicans_SC5314:490833 to 489073 | JBrowse
Note: this feature is encoded on the Crick strand.
Allele Location
Allele C3_02260C_B 		Ca22chr3B_C_albicans_SC5314:490874 to 489114 | JBrowse
Note: this feature is encoded on the Crick strand.
Last UpdateCoordinates: 2016年06月22日 | Sequence: 2016年06月22日

Subfeature Details
Relative
Coordinates		Chromosomal
Coordinates		Most Recent Update
CoordinatesSequence
CDS 1to1761490,874to489,1142016年06月22日2016年06月22日

Allele Location
Allele C3_02260C_B Ca22chr3B_C_albicans_SC5314:490874 to 489114 | JBrowse
Note: this feature is encoded on the Crick strand.
External Links CGOB | Entrez Gene (1, 2) | Fungal Orthologs | FungiDB | GenBank (1, 2, 3, 4, 5, 6) | Non-periodic Expression | Pedant | PhylomeDB | TrEMBL
Primary CGDID CAL0000185956
ADDITIONAL INFORMATION for C3_02260C
Gene/Sequence Resources
REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for C3_02260C_A]
1) Maglott D, et al. (2007) Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res 35(Database issue):D26-31
CGD Papers Entry Pubmed Entry Reference LINKOUT Reference LINKOUT Reference LINKOUT Reference LINKOUT Reference LINKOUT
2) CandidaDB
CGD Papers Entry
3) Berman J (2005) Mapping of ORFs in Assembly 4 to those in Assembly 19.
CGD Papers Entry
4) CGD (2005) CGD comparison of orf6 and orf19 predicted protein products.
CGD Papers Entry
5) Mitchell AP (2009) Possibly essential genes; no disruptants obtained by UAU1 method using the BWP17 strain
CGD Papers Entry

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