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Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation Show undefined attributes

authored

[InstanceEdit:847735] Shamovsky, V, 2010年06月01日

category binding

compartment

created [InstanceEdit:975168] Shamovsky, V, 2010年09月22日

dbId 975097

displayName Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation

edited

[InstanceEdit:1014262] Shamovsky, V, 2010年11月15日

eventOf

[Pathway:R-HSA-975163] IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation - Homo sapiens

followingEvent

[Reaction:R-HSA-975103] Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation - Homo sapiens

input

isChimeric false

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

name

Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation

orthologousEvent

output

[Complex:R-HSA-975099] p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [endosome membrane]

precedingEvent

releaseDate 2010年12月14日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:983288] Gillespie, ME, 2010年10月29日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-975097

summation

[Summation:447018] TAK1-binding protein 2 (TAB2) and/or TAB3, as part of a comp...

updateTrackers

Referrals

(updatedInstance)

(hasEvent)

[Pathway:R-HSA-975163] IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation

(precedingEvent)

[Reaction:R-HSA-975103] Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation

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