Reactome Pathway Database

Schema > Reaction > Entries

Tryptophan is hydroxylated Show undefined attributes

authored

[InstanceEdit:378946] Jassal, Bijay, 2008年10月01日

catalystActivity

[CatalystActivity:209966] tryptophan 5-monooxygenase activity of TPH:Fe++ [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:209970] Jassal, Bijay, 2008年01月08日

dbId 209828

deleted

[Deleted:660237] Deletion of instance: 379379

displayName Tryptophan is hydroxylated

edited

[InstanceEdit:209970] Jassal, Bijay, 2008年01月08日

eventOf

[Pathway:R-HSA-209931] Serotonin and melatonin biosynthesis - Homo sapiens

followingEvent

[Reaction:R-HSA-209859] Decarboxylation of 5-hydroxytryptophan forms serotonin - Homo sapiens

input

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10948619] Weiser, Joel, 2025年08月27日

name

Tryptophan is hydroxylated

orthologousEvent

output

releaseDate 2008年06月30日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:351775] D'Eustachio, P, 2008年05月28日 08:30:54

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-209828

summation

[Summation:209975] The first and rate limiting step in serotonin (5-HT) biosynt...

updateTrackers

[UpdateTracker:9790124] Update Tracker - [Reaction:209828] Tryptophan is hydroxylated - v35:[addLiteratureReference, modifyText]

Referrals

(updatedInstance)

[UpdateTracker:9790124] Update Tracker - [Reaction:209828] Tryptophan is hydroxylated - v35:[addLiteratureReference, modifyText]

(replacementInstances)

[Deleted:660237] Deletion of instance: 379379

(hasEvent)

[Pathway:R-HSA-209931] Serotonin and melatonin biosynthesis

(precedingEvent)

[Reaction:R-HSA-209859] Decarboxylation of 5-hydroxytryptophan forms serotonin

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