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Schema
>
Reaction
>
Entries
Decarboxylation of 5-hydroxytryptophan forms serotonin
Show undefined attributes
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catalystActivity
[CatalystActivity:209894] aromatic-L-amino-acid decarboxylase activity of DDC dimer [cytosol]
category
transition
compartment
[Compartment:70101] cytosol
created
[InstanceEdit:209970] Jassal, Bijay, 2008年01月08日
crossReference
[DatabaseIdentifier:12610464] Rhea:18534
dbId
209859
deleted
[Deleted:660237] Deletion of instance: 379379
displayName
Decarboxylation of 5-hydroxytryptophan forms serotonin
edited
[InstanceEdit:209970] Jassal, Bijay, 2008年01月08日
eventOf
[Pathway:R-HSA-209931] Serotonin and melatonin biosynthesis - Homo sapiens
followingEvent
[Reaction:R-HSA-209792] N-acetylation of serotonin - Homo sapiens
[Reaction:R-HSA-380586] loading of Serotonin in synaptic vesicles - Homo sapiens
input
[SimpleEntity:R-ALL-209911] 5HTP [cytosol]
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:209786] Molecular cloning of genomic DNA and chromosomal assignment of the gene for human aromatic L-amino acid decarboxylase, the enzyme for catecholamine and serotonin biosynthesis
[LiteratureReference:209779] Isolation and characterization of a cDNA clone encoding human aromatic L-amino acid decarboxylase
maxDepth
1
modified
[InstanceEdit:10867632] Weiser, Joel, 2025年08月27日
name
Decarboxylation of 5-hydroxytryptophan forms serotonin
orthologousEvent
[Reaction:R-CEL-209859] Decarboxylation of 5-hydroxytryptophan forms serotonin - Caenorhabditis elegans
[Reaction:R-DME-209859] Decarboxylation of 5-hydroxytryptophan forms serotonin - Drosophila melanogaster
[Reaction:R-GGA-209859] Decarboxylation of 5-hydroxytryptophan forms serotonin - Gallus gallus
[Reaction:R-XTR-209859] Decarboxylation of 5-hydroxytryptophan forms serotonin - Xenopus tropicalis
[Reaction:R-DRE-209859] Decarboxylation of 5-hydroxytryptophan forms serotonin - Danio rerio
[Reaction:R-SSC-209859] Decarboxylation of 5-hydroxytryptophan forms serotonin - Sus scrofa
[Reaction:R-BTA-209859] Decarboxylation of 5-hydroxytryptophan forms serotonin - Bos taurus
[Reaction:R-CFA-209859] Decarboxylation of 5-hydroxytryptophan forms serotonin - Canis familiaris
[Reaction:R-RNO-209859] Decarboxylation of 5-hydroxytryptophan forms serotonin - Rattus norvegicus
[Reaction:R-MMU-209859] Decarboxylation of 5-hydroxytryptophan forms serotonin - Mus musculus
output
[SimpleEntity:R-ALL-209914] 5HT [cytosol]
[SimpleEntity:R-ALL-113528] CO2 [cytosol]
precedingEvent
[Reaction:R-HSA-209828] Tryptophan is hydroxylated - Homo sapiens
releaseDate
2008年06月30日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:351775] D'Eustachio, P, 2008年05月28日 08:30:54
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-209859
summation
[Summation:209927] Aromatic L-amino acid decarboxylase (AADC) catalyzes the dec...
Referrals
(replacementInstances)
[Deleted:660237] Deletion of instance: 379379
(hasEvent)
[Pathway:R-HSA-209931] Serotonin and melatonin biosynthesis
(precedingEvent)
[Reaction:R-HSA-209792] N-acetylation of serotonin
[Reaction:R-HSA-380586] loading of Serotonin in synaptic vesicles
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