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Schema
>
SimpleEntity
>
Entries
MAL [cytosol]
Show undefined attributes
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compartment
[Compartment:70101] cytosol
consumedByEvent
[Reaction:R-GGA-376887] 2-oxoglutarate [mitochondrial matrix] + malate [cytosol] <=> 2-oxoglutarate [cytosol] + malate [mitochondrial matrix] - Gallus gallus
[Reaction:R-GGA-372855] malate + NAD+ <=> oxaloacetate + NADH + H+ - Gallus gallus
[Reaction:R-HSA-376851] SLC25A11 exchanges 2-OG and MAL - Homo sapiens
[Reaction:R-CEL-9012036] ME1 tetramer decarboxylates MAL to PYR - Caenorhabditis elegans
[Reaction:R-DME-9012036] ME1 tetramer decarboxylates MAL to PYR - Drosophila melanogaster
[Reaction:R-GGA-9012036] ME1 tetramer decarboxylates MAL to PYR - Gallus gallus
[Reaction:R-DRE-9012036] ME1 tetramer decarboxylates MAL to PYR - Danio rerio
[Reaction:R-SSC-9012036] ME1 tetramer decarboxylates MAL to PYR - Sus scrofa
[Reaction:R-BTA-9012036] ME1 tetramer decarboxylates MAL to PYR - Bos taurus
[Reaction:R-CFA-9012036] ME1 tetramer decarboxylates MAL to PYR - Canis familiaris
[Reaction:R-RNO-9012036] ME1 tetramer decarboxylates MAL to PYR - Rattus norvegicus
[Reaction:R-SCE-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate - Saccharomyces cerevisiae
[Reaction:R-DDI-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate - Dictyostelium discoideum
[Reaction:R-CEL-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate - Caenorhabditis elegans
[Reaction:R-DME-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate - Drosophila melanogaster
[Reaction:R-GGA-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate - Gallus gallus
[Reaction:R-DRE-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate - Danio rerio
[Reaction:R-SSC-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate - Sus scrofa
[Reaction:R-DRE-376851] SLC25A11 exchanges 2-OG and MAL - Danio rerio
[Reaction:R-RNO-376851] SLC25A11 exchanges 2-OG and MAL - Rattus norvegicus
[Reaction:R-MMU-376851] SLC25A11 exchanges 2-OG and MAL - Mus musculus
[Reaction:R-CFA-376851] SLC25A11 exchanges 2-OG and MAL - Canis familiaris
[Reaction:R-GGA-376851] SLC25A11 exchanges 2-OG and MAL - Gallus gallus
[Reaction:R-SSC-376851] SLC25A11 exchanges 2-OG and MAL - Sus scrofa
[Reaction:R-XTR-376851] SLC25A11 exchanges 2-OG and MAL - Xenopus tropicalis
[Reaction:R-CEL-376851] SLC25A11 exchanges 2-OG and MAL - Caenorhabditis elegans
[Reaction:R-DME-376851] SLC25A11 exchanges 2-OG and MAL - Drosophila melanogaster
[Reaction:R-BTA-376851] SLC25A11 exchanges 2-OG and MAL - Bos taurus
[Reaction:R-PFA-376851] SLC25A11 exchanges 2-OG and MAL - Plasmodium falciparum
[Reaction:R-HSA-9012036] ME1 tetramer decarboxylates MAL to PYR - Homo sapiens
[Reaction:R-MMU-9012036] ME1 tetramer decarboxylates MAL to PYR - Mus musculus
[Reaction:R-MMU-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate - Mus musculus
[Reaction:R-HSA-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate - Homo sapiens
[Reaction:R-RNO-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate - Rattus norvegicus
[Reaction:R-CFA-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate - Canis familiaris
[Reaction:R-BTA-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate - Bos taurus
[Reaction:R-SPO-75849] SLC25A1 exchanges CIT and MAL - Schizosaccharomyces pombe
[Reaction:R-XTR-75849] SLC25A1 exchanges CIT and MAL - Xenopus tropicalis
[Reaction:R-SCE-75849] SLC25A1 exchanges CIT and MAL - Saccharomyces cerevisiae
[Reaction:R-CEL-75849] SLC25A1 exchanges CIT and MAL - Caenorhabditis elegans
[Reaction:R-DME-75849] SLC25A1 exchanges CIT and MAL - Drosophila melanogaster
[Reaction:R-GGA-75849] SLC25A1 exchanges CIT and MAL - Gallus gallus
[Reaction:R-DRE-75849] SLC25A1 exchanges CIT and MAL - Danio rerio
[Reaction:R-SSC-75849] SLC25A1 exchanges CIT and MAL - Sus scrofa
[Reaction:R-HSA-75849] SLC25A1 exchanges CIT and MAL - Homo sapiens
[Reaction:R-MMU-75849] SLC25A1 exchanges CIT and MAL - Mus musculus
[Reaction:R-RNO-75849] SLC25A1 exchanges CIT and MAL - Rattus norvegicus
[Reaction:R-CFA-75849] SLC25A1 exchanges CIT and MAL - Canis familiaris
[Reaction:R-BTA-75849] SLC25A1 exchanges CIT and MAL - Bos taurus
created
[InstanceEdit:198480] D'Eustachio, P, 2007年06月22日 14:17:01
crossReference
[DatabaseIdentifier:29637] COMPOUND:C00149
dbId
198498
displayName
MAL [cytosol]
inDisease
false
maxDepth
1
modified
[InstanceEdit:9760981] D'Eustachio, Peter, 2022年01月05日
name
MAL
(S)-Malate
(S)-malic acid
L-Malate
L-Apple acid
L-Malic acid
L-2-Hydroxybutanedioic acid
producedByEvent
[Reaction:R-GGA-372852] malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix] - Gallus gallus
[Reaction:R-PFA-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Plasmodium falciparum
[Reaction:R-XTR-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Xenopus tropicalis
[Reaction:R-SCE-372843] SLC25A10 mediates exchange of malate and phosphate - Saccharomyces cerevisiae
[Reaction:R-DDI-372843] SLC25A10 mediates exchange of malate and phosphate - Dictyostelium discoideum
[Reaction:R-CEL-372843] SLC25A10 mediates exchange of malate and phosphate - Caenorhabditis elegans
[Reaction:R-CEL-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Caenorhabditis elegans
[Reaction:R-DME-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Drosophila melanogaster
[Reaction:R-DME-372843] SLC25A10 mediates exchange of malate and phosphate - Drosophila melanogaster
[Reaction:R-GGA-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Gallus gallus
[Reaction:R-GGA-372843] SLC25A10 mediates exchange of malate and phosphate - Gallus gallus
[Reaction:R-DRE-372843] SLC25A10 mediates exchange of malate and phosphate - Danio rerio
[Reaction:R-DRE-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Danio rerio
[Reaction:R-SSC-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Sus scrofa
[Reaction:R-SSC-372843] SLC25A10 mediates exchange of malate and phosphate - Sus scrofa
[Reaction:R-DRE-9856871] MDH1 reduces OA - Danio rerio
[Reaction:R-HSA-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Homo sapiens
[Reaction:R-HSA-372843] SLC25A10 mediates exchange of malate and phosphate - Homo sapiens
[Reaction:R-GGA-9856871] MDH1 reduces OA - Gallus gallus
[Reaction:R-SSC-9856871] MDH1 reduces OA - Sus scrofa
[Reaction:R-HSA-9856871] MDH1 reduces OA - Homo sapiens
[Reaction:R-MMU-9856871] MDH1 reduces OA - Mus musculus
[Reaction:R-RNO-9856871] MDH1 reduces OA - Rattus norvegicus
[Reaction:R-CFA-9856871] MDH1 reduces OA - Canis familiaris
[Reaction:R-BTA-9856871] MDH1 reduces OA - Bos taurus
[Reaction:R-XTR-9856871] MDH1 reduces OA - Xenopus tropicalis
[Reaction:R-CEL-9856871] MDH1 reduces OA - Caenorhabditis elegans
[Reaction:R-DME-9856871] MDH1 reduces OA - Drosophila melanogaster
[Reaction:R-DDI-9856871] MDH1 reduces OA - Dictyostelium discoideum
[Reaction:R-MMU-372843] SLC25A10 mediates exchange of malate and phosphate - Mus musculus
[Reaction:R-MMU-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Mus musculus
[Reaction:R-RNO-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Rattus norvegicus
[Reaction:R-RNO-372843] SLC25A10 mediates exchange of malate and phosphate - Rattus norvegicus
[Reaction:R-CFA-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Canis familiaris
[Reaction:R-CFA-372843] SLC25A10 mediates exchange of malate and phosphate - Canis familiaris
[Reaction:R-BTA-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Bos taurus
[Reaction:R-BTA-372843] SLC25A10 mediates exchange of malate and phosphate - Bos taurus
referenceEntity
[ReferenceMolecule:chebi:15589] (S)-malate(2-) [ChEBI:15589]
referenceType
ReferenceMolecule
schemaClass
SimpleEntity
stId
R-ALL-198498
updateTrackers
[UpdateTracker:9874525] Update Tracker - [SimpleEntity:198498] MAL [cytosol] - v43:[addName]
[UpdateTracker:9903220] Update Tracker - [SimpleEntity:198498] MAL [cytosol] - v80:[add_removeReferenceEntity]
[UpdateTracker:9891324] Update Tracker - [SimpleEntity:198498] MAL [cytosol] - v52:[addName]
Referrals
(input)
[Reaction:R-GGA-376887] 2-oxoglutarate [mitochondrial matrix] + malate [cytosol] <=> 2-oxoglutarate [cytosol] + malate [mitochondrial matrix]
[Reaction:R-GGA-372855] malate + NAD+ <=> oxaloacetate + NADH + H+
[Reaction:R-HSA-376851] SLC25A11 exchanges 2-OG and MAL
[Reaction:R-SPO-75849] SLC25A1 exchanges CIT and MAL
[Reaction:R-XTR-75849] SLC25A1 exchanges CIT and MAL
[Reaction:R-CEL-9012036] ME1 tetramer decarboxylates MAL to PYR
[Reaction:R-DME-9012036] ME1 tetramer decarboxylates MAL to PYR
[Reaction:R-GGA-9012036] ME1 tetramer decarboxylates MAL to PYR
[Reaction:R-DRE-9012036] ME1 tetramer decarboxylates MAL to PYR
[Reaction:R-SSC-9012036] ME1 tetramer decarboxylates MAL to PYR
[Reaction:R-BTA-9012036] ME1 tetramer decarboxylates MAL to PYR
[Reaction:R-CFA-9012036] ME1 tetramer decarboxylates MAL to PYR
[Reaction:R-RNO-9012036] ME1 tetramer decarboxylates MAL to PYR
[Reaction:R-SCE-75849] SLC25A1 exchanges CIT and MAL
[Reaction:R-SCE-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate
[Reaction:R-DDI-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate
[Reaction:R-CEL-75849] SLC25A1 exchanges CIT and MAL
[Reaction:R-CEL-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate
[Reaction:R-DME-75849] SLC25A1 exchanges CIT and MAL
[Reaction:R-DME-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate
[Reaction:R-GGA-75849] SLC25A1 exchanges CIT and MAL
[Reaction:R-GGA-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate
[Reaction:R-DRE-75849] SLC25A1 exchanges CIT and MAL
[Reaction:R-DRE-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate
[Reaction:R-SSC-75849] SLC25A1 exchanges CIT and MAL
[Reaction:R-SSC-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate
[Reaction:R-DRE-376851] SLC25A11 exchanges 2-OG and MAL
[Reaction:R-RNO-376851] SLC25A11 exchanges 2-OG and MAL
[Reaction:R-HSA-75849] SLC25A1 exchanges CIT and MAL
[Reaction:R-MMU-376851] SLC25A11 exchanges 2-OG and MAL
[Reaction:R-CFA-376851] SLC25A11 exchanges 2-OG and MAL
[Reaction:R-GGA-376851] SLC25A11 exchanges 2-OG and MAL
[Reaction:R-SSC-376851] SLC25A11 exchanges 2-OG and MAL
[Reaction:R-XTR-376851] SLC25A11 exchanges 2-OG and MAL
[Reaction:R-CEL-376851] SLC25A11 exchanges 2-OG and MAL
[Reaction:R-DME-376851] SLC25A11 exchanges 2-OG and MAL
[Reaction:R-BTA-376851] SLC25A11 exchanges 2-OG and MAL
[Reaction:R-PFA-376851] SLC25A11 exchanges 2-OG and MAL
[Reaction:R-HSA-9012036] ME1 tetramer decarboxylates MAL to PYR
[Reaction:R-MMU-9012036] ME1 tetramer decarboxylates MAL to PYR
[Reaction:R-MMU-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate
[Reaction:R-MMU-75849] SLC25A1 exchanges CIT and MAL
[Reaction:R-HSA-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate
[Reaction:R-RNO-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate
[Reaction:R-RNO-75849] SLC25A1 exchanges CIT and MAL
[Reaction:R-CFA-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate
[Reaction:R-CFA-75849] SLC25A1 exchanges CIT and MAL
[Reaction:R-BTA-1614546] Sulfate is exported to the cytosol in exchange for dicarboxylate
[Reaction:R-BTA-75849] SLC25A1 exchanges CIT and MAL
(output)
[Reaction:R-GGA-372852] malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix]
[Reaction:R-PFA-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane
[Reaction:R-XTR-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane
[Reaction:R-SCE-372843] SLC25A10 mediates exchange of malate and phosphate
[Reaction:R-DDI-372843] SLC25A10 mediates exchange of malate and phosphate
[Reaction:R-CEL-372843] SLC25A10 mediates exchange of malate and phosphate
[Reaction:R-CEL-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane
[Reaction:R-DME-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane
[Reaction:R-DME-372843] SLC25A10 mediates exchange of malate and phosphate
[Reaction:R-GGA-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane
[Reaction:R-GGA-372843] SLC25A10 mediates exchange of malate and phosphate
[Reaction:R-DRE-372843] SLC25A10 mediates exchange of malate and phosphate
[Reaction:R-DRE-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane
[Reaction:R-SSC-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane
[Reaction:R-SSC-372843] SLC25A10 mediates exchange of malate and phosphate
[Reaction:R-DRE-9856871] MDH1 reduces OA
[Reaction:R-HSA-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane
[Reaction:R-HSA-372843] SLC25A10 mediates exchange of malate and phosphate
[Reaction:R-GGA-9856871] MDH1 reduces OA
[Reaction:R-SSC-9856871] MDH1 reduces OA
[Reaction:R-HSA-9856871] MDH1 reduces OA
[Reaction:R-MMU-9856871] MDH1 reduces OA
[Reaction:R-RNO-9856871] MDH1 reduces OA
[Reaction:R-CFA-9856871] MDH1 reduces OA
[Reaction:R-BTA-9856871] MDH1 reduces OA
[Reaction:R-XTR-9856871] MDH1 reduces OA
[Reaction:R-CEL-9856871] MDH1 reduces OA
[Reaction:R-DME-9856871] MDH1 reduces OA
[Reaction:R-DDI-9856871] MDH1 reduces OA
[Reaction:R-MMU-372843] SLC25A10 mediates exchange of malate and phosphate
[Reaction:R-MMU-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane
[Reaction:R-RNO-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane
[Reaction:R-RNO-372843] SLC25A10 mediates exchange of malate and phosphate
[Reaction:R-CFA-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane
[Reaction:R-CFA-372843] SLC25A10 mediates exchange of malate and phosphate
[Reaction:R-BTA-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane
[Reaction:R-BTA-372843] SLC25A10 mediates exchange of malate and phosphate
(updatedInstance)
[UpdateTracker:9874525] Update Tracker - [SimpleEntity:198498] MAL [cytosol] - v43:[addName]
[UpdateTracker:9903220] Update Tracker - [SimpleEntity:198498] MAL [cytosol] - v80:[add_removeReferenceEntity]
[UpdateTracker:9891324] Update Tracker - [SimpleEntity:198498] MAL [cytosol] - v52:[addName]
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