Reactome Pathway Database

Schema > Reaction > Entries

MDH1 reduces OA Show undefined attributes

catalystActivity

[CatalystActivity:10598665] L-malate dehydrogenase (NAD+) activity of MDH1 dimer [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10541496] Weiser, Joel, 2025年08月27日

dbId 10598667

displayName MDH1 reduces OA

eventOf

[Pathway:R-DRE-9856872] Malate-aspartate shuttle - Danio rerio

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-DRE-376851] SLC25A11 exchanges 2-OG and MAL - Danio rerio

inferredFrom

[Reaction:R-HSA-9856871] MDH1 reduces OA - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

MDH1 reduces OA

output

precedingEvent

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:68323] Danio rerio

stId R-DRE-9856871

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-DRE-9856872] Malate-aspartate shuttle

(precedingEvent)

[Reaction:R-DRE-376851] SLC25A11 exchanges 2-OG and MAL

(inferredTo)

[Reaction:R-HSA-9856871] MDH1 reduces OA

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