SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane

authored
catalystActivity
catalystActivityReference [CatalystActivityReference:9815400] oxoglutarate:malate antiporter activity of SLC25A11 homodimer [mitochondrial inner membrane] Porphyrin accumulation in mitochondria is mediated by 2-oxoglutarate carrier
category transition
compartment
created [InstanceEdit:198480] D'Eustachio, P, 2007年06月22日 14:17:01
crossReference
dbId 198440
displayName SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane
edited
eventOf
followingEvent
input
isInDisease false
isInferred false
literatureReference
maxDepth 1
modified [InstanceEdit:11064438] Weiser, Joel, 2025年08月28日
name
  • SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane
  • (S)-malate(in) + 2-oxoglutarate(out) => (S)-malate(out) + 2-oxoglutarate(in)
orthologousEvent
output
precedingEvent
releaseDate 2005年09月26日
reverseReaction [Reaction:R-HSA-376851] SLC25A11 exchanges 2-OG and MAL
reviewStatus [ReviewStatus:9821382] five stars
reviewed
revised
schemaClass Reaction
species
stId R-HSA-198440
summation
updateTrackers
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