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KCNH6

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
KCNH6
Identifiers
Aliases KCNH6 , ERG-2, ERG2, HERG2, Kv11.2, hERG-2, potassium voltage-gated channel subfamily H member 6
External IDsOMIM: 608168; MGI: 2684139; HomoloGene: 32740; GeneCards: KCNH6; OMA:KCNH6 - orthologs
Gene location (Human)
Chromosome 17 (human)
Chr. Chromosome 17 (human) [1]
Band 17q23.3Start63,523,334 bp [1]
End63,548,977 bp [1]
Gene location (Mouse)
Chromosome 11 (mouse)
Chr. Chromosome 11 (mouse)[2]
Band 11|11 E1Start106,008,124 bp [2]
End106,034,549 bp [2]
RNA expression pattern
Bgee
Human Mouse (ortholog)
  • buccal mucosa cell

  • gonad

  • human kidney

  • testicle

  • anterior pituitary

  • islet of Langerhans

  • jejunal mucosa

  • prostate

  • duodenum

  • renal medulla
  • islet of Langerhans

  • layer of retina

  • neural layer of retina

  • optic nerve

  • molecular layer of cerebellar cortex

  • epiblast

  • granular layer

  • embryo

  • Purkinje cell

  • inferior colliculi
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

81033

192775

Ensembl

ENSG00000173826

ENSMUSG00000001901

UniProt

Q9H252

n/a

RefSeq (mRNA)

NM_001278919
NM_001278920
NM_030779
NM_173092

NM_001037712

RefSeq (protein)

NP_001265848
NP_001265849
NP_110406
NP_775115

n/a

Location (UCSC)Chr 17: 63.52 – 63.55 Mb Chr 11: 106.01 – 106.03 Mb
PubMed search[3] [4]
Wikidata

Potassium voltage-gated channel subfamily H member 6 is a protein that in humans is encoded by the KCNH6 gene.[5] The protein encoded by this gene is a voltage-gated potassium channel subunit.[5]

References

[edit ]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000173826Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000001901Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

Further reading

[edit ]
[edit ]
Ligand-gated
Voltage-gated
Constitutively active
Proton-gated
Voltage-gated
Calcium-activated
Inward-rectifier
Tandem pore domain
Voltage-gated
Miscellaneous
Cl: Chloride channel
H+: Proton channel
M+: CNG cation channel
M+: TRP cation channel
H2O (+ solutes): Porin
Cytoplasm: Gap junction
By gating mechanism
Ion channel class
see also disorders


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