α-Difluoromethyl-DOPA
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(Redirected from Alpha-Difluoromethyl-DOPA)
| Names | |
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| Systematic IUPAC name
(2S)-2-Amino-2-[(3,4-dihydroxyphenyl)methyl]-3,3-difluoropropanoic acid | |
| Other names
α-(Difluoromethyl)-3-hydroxy-L-tyrosine
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| Identifiers | |
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3D model (JSmol)
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| ChemSpider |
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| MeSH | alpha-difluoromethyl-DOPA |
PubChem CID
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| UNII |
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CompTox Dashboard (EPA)
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| Properties | |
| C10H11F2NO4 | |
| Molar mass | 247.20 g/mol |
| Density | 1.528 g/mL |
| Boiling point | 479 °C (894 °F; 752 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
α-Difluoromethyl-3,4-dihydroxyphenylalanine (DFMD, DFM-DOPA) is a DOPA decarboxylase inhibitor.[1]
See also
[edit ]References
[edit ]- ^ Zbinden G, Brändle E (February 1980). "Inhibition of 5-hydroxytryptophan nephrotoxicity by alpha-difluoromethyl-dopa, an inhibitor or L-amino acid decarboxylase". Toxicology Letters . 5 (2): 125–9. doi:10.1016/0378-4274(80)90161-7. PMID 6781106.