髙久 洋暁

論文

• Efficient Vitamin A Production in Lipomyces starkeyi through Metabolic Engineering of the β-Carotene and Retinoid Pathways

  Akari Kinoshita, Rikako Sato, Hibiki Higuchi, Shunichi Kobayashi, Kento Koketsu, Taro Watanabe, and Hiroaki Takaku

  Microbial Cell Factories 2026年5月 査読有り最終著者責任著者
• A CRISPR/Cas9-based genome-editing platform enabling efficient and precise gene replacement in Lipomyces starkeyi

  Rikako Satoa, Kaito Maruyamaa, Satoshi Arab, Masayuki Shibatab, Yosuke Shidac, Wataru Ogasawarac, Harutake Yamazakia, Hiroaki Takaku

  FEMS Yeast Research 2026年4月 査読有り最終著者責任著者
• Metabolic pathway of the rare sugar 5-keto-D-fructose in the oleaginous yeast Lipomyces starkeyi

  Yukie Noyori, Rikako Sato, Kei Takeshita, Kazuki Mori, Kosuke Tashiro, Yujiro Higuchi, Hiromi Maekawa, Hiroaki Takaku, and Kaoru Takegawa

  Journal of Bioscience and Bioengineering 2026年1月 査読有り
• Lipid metabolism prediction in oleaginous yeasts across taxonomic levels using single-cell innate fluorescence signature

  Shiomi Yawata, Tomohiro Hirayama, Tatsuro Serita, Haruka Kazama, Koji Mori, Hiroaki Takaku, Nobuhiko Nomura, Yutaka Yawata

  Journal of Bioscience and Bioengineering 2025年10月 査読有り
• Effects of inorganic nitrogen addition to okara-utilized medium on the oleaginous yeast Lipomyces starkeyi and assessment of metabolism involved in increased oil production

  Hiroya Taki, Kentaro Mine, Mana Miyamoto, Juyoung Kim, Jiro Seto, Hiroaki Takaku, Kazuo Kumagai & Hideto Matsuyama

  Biotechnology for Biofuels and Bioproducts 18 2025年9月 査読有り
• Ultrahigh-throughput screening of environmental bacteria for proteolytic activity using droplet-based microfluidics

  Akihiro Nakamura, Yoshiyuki Suzuki, Nobuyuki Homma, Yosuke Shida, Rikako Sato, Hiroaki Takaku, Wataru Ogasawara

  Applied and Environmental Microbiology 2025年6月 査読有り
• Sustainable and efficient vegetable oil substitute production by oleaginous yeast Lipomyces starkeyi

  Rikako Sato, Harutake Yamazaki, and Hiroaki Takaku

  The 10th RSU International Research Conference 2025年4月 招待有り最終著者責任著者
• Transcriptomic analysis reveals three important carbohydrate-active enzymes contributing to starch degradation of oleaginous yeast Lipomyces starkeyi

  Kentaro Mine, Hiroya Taki, Juyoung Kim, Jiro Seto, Shinji Matsuo, Rikako Sato, Hiroaki Takaku

  Bioscience, Biotechnology, and Biochemistry 89(3) 446-458 2025年3月 査読有り最終著者責任著者
• Identification and characterization of the suppressed lipid accumulation-related gene, SLA1, in the oleaginous yeast Lipomyces starkeyi

  Rikako Sato, Harutake Yamazaki, Kazuki Mori, Sachiyo Aburatani, Koji Ishiya, Yosuke Shida, Wataru Ogasawara, Kosuke Tashiro, Satoru Kuhara, Hiroaki Takaku

  Bioscience, Biotechnology, and Biochemistry 2024年7月31日
• Deletion of LsSNF1 enhances lipid accumulation in the oleaginous yeast Lipomyces starkeyi

  Rikako Sato, Yuuya Fujii, Satoshi Ara, Harutake Yamazaki, Sachiyo Aburatani, Wataru Ogasawara, Hiroaki Takaku

  Journal of Bioscience and Bioengineering 137(4) 260-267 2024年4月
• Deletion of LsSNF1 enhances lipid accumulation in the oleaginous yeast Lipomyces starkeyi

  Rikako Sato, Yuuya Fujii, Satoshi Ara, Harutake Yamazaki, Sachiyo Aburatani, Wataru Ogasawara, and Hiroaki Takaku

  Journal of Bioscience and Bioengineering 2024年1月 査読有り
• Optimization of the CRISPR/Cas9 system using adh1 promoter derivatives in fission yeast

  Miori Saito, Hidenori Nakaoka, Aki Hayashi, Hiroaki Takaku, Harutake Yamazaki

  microPublication Biology 2023年2月3日 査読有り
• Computational approaches for smart cell creation in the bioeconomy era

  Sachiyo Aburatani, Koji Ishiya, Tomokazu Shirai, Yosuke Shida, Wataru Ogasawara, Hiroaki Takaku, Tomohiro Tamura

  Genomics and the Global Bioeconomy 59-82 2023年
• LsSpt23p is a regulator of triacylglycerol synthesis in the oleaginous yeast Lipomyces starkeyi

  Hiroaki Takaku, Haruka Kazama, Rikako Sato, Kazuki Mori, Satoshi Ara, Koji Ishiya, Tomohiko Matsuzawa, Katsuro Yaoi, Hideo Araki, Yosuke Shida …

  Applied Microbiology and Biotechnology 107(4) 1269-1284 2023年1月 査読有り
• Citrate-Mediated Acyl-CoA Synthesis Is Required for the Promotion of Growth and Triacylglycerol Production in Oleaginous Yeast Lipomyces starkeyi

  Rikako Sato, Satoshi Ara, Harutake Yamazaki, Koji Ishiya, Sachiyo Aburatani and Hiroaki Takaku

  Microorganisms 9(8) 1693 2021年8月 査読有り最終著者責任著者
• Analysis of the light regulatory mechanism in carotenoid production in Rhodosporidium toruloides NBRC 10032

  Khanh Dung Pham, Yuuki Hakozaki, Takeru Takamizawa, Atsushi Yamazaki, Harutake Yamazaki, Kazuki Mori, Sachiyo Aburatani, Kosuke Tashiro, Satoru Kuhara, HiroakiTakaku …

  Bioscience, Biotechnology, and Biochemistry 85(8) 1899-1909 2021年6月 査読有り
• Isolation and characterization of Lipomyces starkeyi mutants with greatly increased lipid productivity following UV irradiation

  Hiroaki Takaku, Sayaka Ebina, Kotoha Kasuga, Rikako Sato, Satoshi Ara, Haruka Kazama, Tomohiko Matsuzawa, Katsuro Yaoi, Hideo Araki, Yosuke Shida …

  Journal of Bioscience and Bioengineering 131(6) 613-621 2021年2月 査読有り筆頭著者責任著者
• Inference of Regulatory System for TAG Biosynthesis in Lipomyces starkeyi

  Sachiyo Aburatani, Koji Ishiya, Toshikazu Itoh, Toshihiro Hayashi, Takeaki Taniguchi, HiroakiTakaku

  Bioengineering 7(4) 148 2020年11月 査読有り最終著者責任著者
• Identification and characterization of Pseudozyma antarctica Δ12 fatty acid desaturase and its utilization for the production of polyunsaturated fatty acids

  Tomohiko Matsuzawa, Tomoko Maehara, Yasushi Kamisaka, Yuko Ayabe-Chujo, HiroakiTakaku, Katsuro Yaoi

  Journal of Bioscience and Bioengineering 130(6) 604-609 2020年8月 査読有り
• Lipid metabolism of the oleaginous yeast Lipomyces starkeyi

  Hiroaki Takaku, Tomohiko Matsuzawa, Katsuro Yaoi, Harutake Yamazaki

  Applied Microbiology and Biotechnology 104(14) 6141-6148 2020年7月26日 査読有り招待有り筆頭著者責任著者