水野 英明

論文

• Neural network-assisted RNA velocity imputation for empowering transcript dynamics-based analyses

  Riku Egami, Momo Shirotori, Takashi Tamura, Sohei Oyama, Hideaki Mizuno

  iScience 2026年3月
• MIF-CD74 axis facilitates MDSC infiltration in the tumor microenvironment of pancreatic ductal adenocarcinoma.

  Fukuda H, Arai K, Hashimoto E, Sekine K, Arai Y, Hiraoka N, Hirata A, Yamashita M, Narumi K, Kikuchi A …

  Cancer letters 2026年2月20日
• EML4–ALK Rearrangement Creates a Distinctive Myeloid Cell–Dominant Immunosuppressive Microenvironment in Lung Cancer

  Kosuke Arai, Yukari Nishito, Hideaki Mizuno, Noriko Motoi, Nobuyoshi Hiraoka, Masanori Fuse, Yasuhito Arai, Tatsuhiro Shibata, Yukiko Sonobe, Yoko Kayukawa …

  Cancer Immunology Research 2025年9月2日
• Supplementary Table S2 from EML4–ALK Rearrangement Creates a Distinctive Myeloid Cell–Dominant Immunosuppressive Microenvironment in Lung Cancer

  Kosuke Arai, Yukari Nishito, Hideaki Mizuno, Noriko Motoi, Nobuyoshi Hiraoka, Masanori Fuse, Yasuhito Arai, Tatsuhiro Shibata, Yukiko Sonobe, Yoko Kayukawa …

  Cancer Immunology Research 13(9) 1435-1452 2025年9月2日
• Optimized digital workflow for pathologist-grade evaluation in bleomycin-induced pulmonary fibrosis mouse model.

  Toshiki Goto, Akira Sano, Shinichi Onishi, Natsuko Hada, Rui Kimata, Saori Matsuo, Sohei Oyama, Atsuhiko Kato, Hideaki Mizuno, Masaki Yamazaki

  Scientific reports 15(1) 2331-2331 2025年1月17日
• Author Correction: Neutrophil-to-lymphocyte ratio is a prognostic factor reflecting immune condition of tumor microenvironment in squamous cell lung cancer.

  Kana Ohashi, Yukari Nishito, Hironori Fukuda, Ryoichi Sadahiro, Yukihiro Yoshida, Shun-Ichi Watanabe, Noriko Motoi, Yukiko Sonobe, Hideaki Mizuno, Hiroyuki Tsunoda …

  Scientific reports 14(1) 30457-30457 2024年12月13日
• Molecular subtypes of lung adenocarcinoma present distinct immune tumor microenvironments

  Hironori Fukuda, Kosuke Arai, Hideaki Mizuno, Yukari Nishito, Noriko Motoi, Yasuhito Arai, Nobuyoshi Hiraoka, Tatsuhiro Shibata, Yukiko Sonobe, Yoko Kayukawa …

  Cancer Science 2024年3月25日
• Neutrophil-to-lymphocyte ratio is a prognostic factor reflecting immune condition of tumor microenvironment in squamous cell lung cancer.

  Kana Ohashi, Yukari Nishito, Hironori Fukuda, Ryoichi Sadahiro, Yukihiro Yoshida, Shun-Ichi Watanabe, Noriko Motoi, Yukiko Sonobe, Hideaki Mizuno, Hiroyuki Tsunoda …

  Scientific reports 14(1) 429-429 2024年1月3日
• Tumor-infiltrating Leukocyte Profiling Defines Three Immune Subtypes of NSCLC with Distinct Signaling Pathways and Genetic Alterations.

  Kazunori Aoki, Yukari Nishito, Noriko Motoi, Yasuhito Arai, Nobuyoshi Hiraoka, Tatsuhiro Shibata, Yukiko Sonobe, Yoko Kayukawa, Eri Hashimoto, Mina Takahashi …

  Cancer research communications 3(6) 1026-1040 2023年6月 査読有り
• Rapid in vitro assessment of the immunogenicity potential of engineered antibody therapeutics through detection of CD4+ T cell interleukin-2 secretion.

  Yoshiyuki Arata, Shigeki Motoyama, Mariko Yano, Tatsuya Ikuno, Shunsuke Ito, Tomochika Matsushita, Akira Takeiri, Yukari Nishito, Nami Yabuki, Hideaki Mizuno …

  mAbs 15(1) 2253570-2253570 2023年
• Digital workflows for pathological assessment of rat estrous cycle stage using images of uterine horn and vaginal tissue

  Onishi, S., Egami, R., Nakamura, Y., Nagashima, Y., Nishihara, K., Matsuo, S., Murai, A., Hayashi, S., Uesumi, Y., Kato, A. …

  Journal of Pathology Informatics 13 100120-100120 2022年6月 査読有り最終著者責任著者
• Geography-Dependent Horizontal Gene Transfer from Vertebrate Predators to Their Prey.

  Chiaki Kambayashi, Ryosuke Kakehashi, Yusuke Sato, Hideaki Mizuno, Hideyuki Tanabe, Andolalao Rakotoarison, Sven Künzel, Nobuaki Furuno, Kazuhiko Ohshima, Yoshinori Kumazawa …

  Molecular biology and evolution 39(4) 2022年4月10日 査読有り
• Anti-GPRC5D/CD3 bispecific T cell-redirecting antibody for the treatment of multiple myeloma.

  Kodama T, Kochi Y, Nakai W, Mizuno H, Baba T, Habu K, Sawada N, Tsunoda H, Shima T, Miyawaki K …

  Molecular cancer therapeutics 18(9) 1555-1564 2019年7月 査読有り
• ERK Signal Suppression and Sensitivity to CH5183284/Debio 1347, a Selective FGFR Inhibitor

  Yoshito Nakanishi, Hideaki Mizuno, Hitoshi Sase, Toshihiko Fujii, Kiyoaki Sakata, Nukinori Akiyama, Yuko Aoki, Masahiro Aoki, Nobuya Ishii

  MOLECULAR CANCER THERAPEUTICS 14(12) 2831-2839 2015年12月 査読有り
• The AURKA/TPX2 axis drives colon tumorigenesis cooperatively with MYC

  Y. Takahashi, P. Sheridan, A. Niida, G. Sawada, R. Uchi, H. Mizuno, J. Kurashige, K. Sugimachi, S. Sasaki, Y. Shimada …

  ANNALS OF ONCOLOGY 26(5) 935-942 2015年5月 査読有り
• The PFA-AMeX method achieves a good balance between the morphology of tissues and the quality of RNA content in DNA microarray analysis with laser-capture microdissection samples

  Takeshi Watanabe, Atsuhiko Kato, Hiromichi Terashima, Koichi Matsubara, Yu Jau Chen, Kenji Adachi, Hideaki Mizuno, Masami Suzuki

  JOURNAL OF TOXICOLOGIC PATHOLOGY 28(1) 41-47 2015年1月 査読有り
• Topological analysis of gene expression arrays identifies high risk molecular subtypes in breast cancer

  Javier Arsuaga, Nils A. Baas, Daniel DeWoskin, Hideaki Mizuno, Aleksandr Pankov, Catherine Park

  APPLICABLE ALGEBRA IN ENGINEERING COMMUNICATION AND COMPUTING 23(1-2) 3-15 2012年4月 査読有り
• Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway

  William A. Freed-Pastor, Hideaki Mizuno, Xi Zhao, Anita Langerod, Sung-Hwan Moon, Ruth Rodriguez-Barrueco, Anthony Barsotti, Agustin Chicas, Wencheng Li, Alla Polotskaia …

  CELL 148(1-2) 244-258 2012年1月 査読有り
• Identification of Genes Upregulated in ALK-Positive and EGFR/KRAS/ALK-Negative Lung Adenocarcinomas

  Hirokazu Okayama, Takashi Kohno, Yuko Ishii, Yoko Shimada, Kouya Shiraishi, Reika Iwakawa, Koh Furuta, Koji Tsuta, Tatsuhiro Shibata, Seiichiro Yamamoto …

  CANCER RESEARCH 72(1) 100-111 2012年1月 査読有り
• Molecular classification of prostate cancer using curated expression signatures

  Elke K. Markert, Hideaki Mizuno, Alexei Vazquez, Arnold J. Levine

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 108(52) 21276-21281 2011年12月 査読有り