中沢 由華

論文

• Hierarchical mechanisms control the clearance of DNA lesion–stalled RNA polymerase II

  Paula J. van der Meer, George Yakoub, Kotaro Tsukada, Yuka Nakazawa, Tomoo Ogi, Martijn S. Luijsterburg

  Nature Communications 2026年1月19日 査読有り
• XP-J, a ninth xeroderma pigmentosum complementation group, results from mutations in GTF2H4, encoding TFIIH-p52 subunit

  Hiva Fassihi*, Shehla Mohammed*, Yuka Nakazawa*, Heather Fawce*, Sally Turner, Joanne Palfrey, Isabel Garrood, Adesoji Abiona, Ana M.S. Morley, Mayuko Shimada …

  Journal of Clinical Investigation 135(22) 2025年9月9日 査読有り筆頭著者
• TFIIH-p52ΔC defines a ninth xeroderma pigmentosum complementation–group XP-J and restores TFIIH stability to p8-defective trichothiodystrophy

  Yuka Nakazawa, Lin Ye, Yasuyoshi Oka, Hironobu Morinaga, Kana Kato, Mayuko Shimada, Kotaro Tsukada, Koyo Tsujikawa, Yosuke Nishio, Hiva Fassihi …

  Journal of Clinical Investigation 135(22) 2025年9月9日 査読有り筆頭著者
• De novo CDKN1C variant in Beckwith–Wiedermann spectrum with atypical complications

  Yuri Moriura, Yosuke Nishio, Shintaro Ichimura, Haruka Noda, Yoshihiro Tanahashi, Hikaru Yamamoto, Yuka Nakazawa, Taichi Oso, Yoshiaki Sato, Toshiki Takenouchi …

  Human Genome Variation 2025年5月28日
• Transcription-coupled repair -mechanisms of action, regulation, and associated human disorders.

  Nakazawa Y, Oka Y, Matsunaga T, Ogi T

  FEBS Letters 2024年12月 査読有り招待有り筆頭著者
• Comparing the severity of epidermolysis bullosa simplex harboring KRT5 variants with the AlphaMissense score.

  Michiya Omi, Takuya Takeichi, Takenori Yoshikawa, Yuki Inoue, Ryo Fukaura, Ikumi Hattori, Yuka Nakazawa, Tatsuhiro Noda, Yoshinao Muro, Masashi Akiyama

  The Journal of dermatology 2024年10月10日
• Clearance of DNA damage-arrested RNAPII is selectively impaired in Cockayne syndrome cells

  Paula J. van der Meer, George Yakoub, Yuka Nakazawa, Tomoo Ogi, Martijn Luijsterburg

  2024年5月18日
• Endogenous aldehyde-induced DNA–protein crosslinks are resolved by transcription-coupled repair

  Yasuyoshi Oka, Yuka Nakazawa, Mayuko Shimada, Tomoo Ogi

  Nature Cell Biology 2024年4月10日 査読有り
• Inducing multiple nicks promotes interhomolog homologous recombination to correct heterozygous mutations in somatic cells.

  Akiko Tomita, Hiroyuki Sasanuma, Tomoo Owa, Yuka Nakazawa, Mayuko Shimada, Takahiro Fukuoka, Tomoo Ogi, Shinichiro Nakada

  Nature communications 14(1) 5607-5607 2023年9月15日
• Deep intronic founder mutations identified in the ERCC4/XPF gene are potential therapeutic targets for a high-frequency form of xeroderma pigmentosum.

  Chikako Senju*, Yuka Nakazawa*, Taichi Oso*, Mayuko Shimada, Kana Kato, Michiko Matsuse, Mariko Tsujimoto, Taro Masaki, Yasushi Miyazaki, Satoshi Fukushima …

  PNAS (Proceedings of the National Academy of Sciences of the United States of America) 120(27) e2217423120 2023年7月4日 査読有り筆頭著者
• A case of Cockayne syndrome with unusually mild clinical manifestations.

  Tsujimoto M, Nakano E, Nakazawa Y, Kanda F, Ueda T, Ogi T, Nishigori C

  Journal of Dermatology. 50(4) 541-545 2023年 査読有り
• Aicardi-Goutières syndrome with SAMHD1 deficiency can be diagnosed by unscheduled DNA synthesis test.

  Chikako Senju, Yuka Nakazawa, Mayuko Shimada, Dai Iwata, Michiko Matsuse, Katsumi Tanaka, Yasushi Miyazaki, Shinichi Moriwaki, Norisato Mitsutake, Tomoo Ogi

  Frontiers in pediatrics 10 1048002-1048002 2022年
• Dealing with transcription-blocking DNA damage: Repair mechanisms, RNA polymerase II processing and human disorders.

  Nan Jia, Chaowan Guo*, Yuka Nakazawa*, Diana van den Heuvel*, Martijn S Luijsterburg, Tomoo Ogi

  DNA Repair 2021年10月
• ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation.

  Yana van der Weegen, Klaas de Lint, Diana van den Heuvel, Yuka Nakazawa, Tycho E T Mevissen, Janne J M van Schie, Marta San Martin Alonso, Daphne E C Boer, Román González-Prieto, Ishwarya V Narayanan …

  Nature cell biology 23(6) 595-607 2021年6月
• Digenic mutations in ALDH2 and ADH5 impair formaldehyde clearance and cause a multisystem disorder, AMeD syndrome

  Yasuyoshi Oka, Motoharu Hamada, Yuka Nakazawa, Hideki Muramatsu, Yusuke Okuno, Koichiro Higasa, Mayuko Shimada, Honoka Takeshima, Katsuhiro Hanada, Taichi Hirano …

  Science Advances 6(51) eabd7197-eabd7197 2020年12月
• Topoisomerase I-driven repair of UV-induced damage in NER-deficient cells.

  Liton Kumar Saha, Mitsuo Wakasugi, Salma Akter, Rajendra Prasad, Samuel H Wilson, Naoto Shimizu, Hiroyuki Sasanuma, Shar-Yin Naomi Huang, Keli Agama, Yves Pommier …

  Proceedings of the National Academy of Sciences of the United States of America 117(25) 14412-14420 2020年6月23日 査読有り
• Biallelic VPS35L pathogenic variants cause 3C/Ritscher-Schinzel-like syndrome through dysfunction of retriever complex.

  Kohji Kato, Yasuyoshi Oka, Hideki Muramatsu, Filipp F Vasilev, Takanobu Otomo, Hisashi Oishi, Yoshihiko Kawano, Hiroyuki Kidokoro, Yuka Nakazawa, Tomoo Ogi …

  Journal of medical genetics 57(4) 245-253 2020年4月 査読有り
• Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair

  Yuka Nakazawa, Yuichiro Hara, Yasuyoshi Oka, Okiru Komine, Diana van den Heuvel, Chaowan Guo, Yasukazu Daigaku, Mayu Isono, Yuxi He, Mayuko Shimada …

  Cell 180(6) 1228-1244.e24 2020年3月 査読有り筆頭著者
• Hailey-Hailey disease with oesophageal involvement due to a previously unreported ATP2C1 mutation.

  Michihiro Kono, Masanari Kodera, Yu Inasaka, Izumi Hasegawa, Yoshinao Muro, Yuka Nakazawa, Tomoo Ogi, Masashi Akiyama

  European journal of dermatology : EJD 2019年8月30日
• JAK/STAT3 and NF-κB Signaling Pathways Regulate Cancer Stem-Cell Properties in Anaplastic Thyroid Cancer Cells.

  Shiraiwa K, Matsuse M, Nakazawa Y, Ogi T, Suzuki K, Saenko V, Xu S, Umezawa K, Yamashita S, Tsukamoto K …

  Thyroid : official journal of the American Thyroid Association 29(5) 674-682 2019年5月