Reactome Pathway Database

Schema > Reaction > Entries

NR1H4 binds DCA, CDCA, LCHA Show undefined attributes

catalystActivity

[CatalystActivity:10494121] bile acid nuclear receptor activity of NR1H4 [nucleoplasm]

category transition

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10494123

displayName NR1H4 binds DCA, CDCA, LCHA

eventOf

[Pathway:R-SSC-159418] Recycling of bile acids and salts - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

inferredFrom

[Reaction:R-HSA-5340195] NR1H4 binds DCA, CDCA, LCHA - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

NR1H4 binds DCA, CDCA, LCHA
FXR binds bile acids

output

[Complex:R-SSC-5340186] NR1H4:DCA,CDCA,LCHA [nucleoplasm]

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-5340195

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-159418] Recycling of bile acids and salts

(precedingEvent)

(inferredTo)

[Reaction:R-HSA-5340195] NR1H4 binds DCA, CDCA, LCHA

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