Reactome Pathway Database

Schema > Reaction > Entries

SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol Show undefined attributes

catalystActivity

[CatalystActivity:10442318] bile acid:sodium symporter activity of SLC10A2 [plasma membrane]

category transition

compartment

[Compartment:876] plasma membrane

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10442320

displayName SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol

eventOf

[Pathway:R-SSC-159418] Recycling of bile acids and salts - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[BlackBoxEvent:R-SSC-9733973] Bile salts bind FABP6 - Sus scrofa

inferredFrom

[Reaction:R-HSA-194187] SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol
Co-transport (influx) of bile salts and acids and sodium ions by ASBT

output

precedingEvent

[Reaction:R-SSC-5340195] NR1H4 binds DCA, CDCA, LCHA - Sus scrofa

regulatedBy

[PositiveRegulation:10442321] Positive regulation by 'NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm]'

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-194187

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-159418] Recycling of bile acids and salts

(precedingEvent)

[BlackBoxEvent:R-SSC-9733973] Bile salts bind FABP6

(inferredTo)

[Reaction:R-HSA-194187] SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol

© 2025 Reactome

Cite Us!