Reactome Pathway Database

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CD274 N-linked glycosylation in ER Show undefined attributes

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authored

catalystActivity

[CatalystActivity:532535] dolichyl-diphosphooligosaccharide-protein glycotransferase activity of OST complex [endoplasmic reticulum membrane]

category transition

compartment

created [InstanceEdit:9931260] Tiwari, Krishna, 2024年12月11日

dbId 9931286

displayName CD274 N-linked glycosylation in ER

edited

[InstanceEdit:9962761] Gillespie, Marc E, 2025年08月08日

eventOf

[Pathway:R-HSA-9931295] PD-L1(CD274) glycosylation and translocation to plasma membrane - Homo sapiens

followingEvent

[BlackBoxEvent:R-HSA-9931262] Transport of N-glycosylated CD274 to Golgi - Homo sapiens

input

isChimeric false

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

name

CD274 N-linked glycosylation in ER

orthologousEvent

output

[EntityWithAccessionedSequence:R-HSA-9931256] N-glycosylated CD274 [endoplasmic reticulum membrane]

precedingEvent

regulatedBy

regulationReference

releaseDate 2025年09月18日

releaseStatus NEW

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:9964122] Hung, Mien-Chie, Yamaguchi, Hirohito, 2025年08月26日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-9931286

summation

[Summation:9938225] PD-L1 (CD274) glycosylation plays a critical role in determi...

Referrals

(precedingEvent)

[BlackBoxEvent:R-HSA-9931262] Transport of N-glycosylated CD274 to Golgi

(hasEvent)

[Pathway:R-HSA-9931295] PD-L1(CD274) glycosylation and translocation to plasma membrane

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