Reactome Pathway Database

Schema > Reaction > Entries

CD274 N-linked glycosylation in ER Show undefined attributes

catalystActivity

[CatalystActivity:10304576] dolichyl-diphosphooligosaccharide-protein glycotransferase activity of OST complex [endoplasmic reticulum membrane]

category transition

compartment

created [InstanceEdit:10201029] Weiser, Joel, 2025年08月27日

dbId 10304581

displayName CD274 N-linked glycosylation in ER

eventOf

[Pathway:R-CFA-9931295] PD-L1(CD274) glycosylation and translocation to plasma membrane - Canis familiaris

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[BlackBoxEvent:R-CFA-9931262] Transport of N-glycosylated CD274 to Golgi - Canis familiaris

inferredFrom

[Reaction:R-HSA-9931286] CD274 N-linked glycosylation in ER - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

CD274 N-linked glycosylation in ER

output

[EntityWithAccessionedSequence:R-CFA-9931256] PDL1 [endoplasmic reticulum membrane]

precedingEvent

[BlackBoxEvent:R-CFA-1112514] JAK activation - Canis familiaris

regulatedBy

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49646] Canis familiaris

stId R-CFA-9931286

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-CFA-9931295] PD-L1(CD274) glycosylation and translocation to plasma membrane

(precedingEvent)

[BlackBoxEvent:R-CFA-9931262] Transport of N-glycosylated CD274 to Golgi

(inferredTo)

[Reaction:R-HSA-9931286] CD274 N-linked glycosylation in ER

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