Reactome Pathway Database

Schema > BlackBoxEvent > Entries

JAK activation Show undefined attributes

authored

[InstanceEdit:1164950] Ray, K, 2010年12月13日

category omitted

compartment

created [InstanceEdit:1112527] Jupe, S, 2010年12月03日

dbId 1112514

displayName JAK activation

edited

[InstanceEdit:1112767] Jupe, S, 2010年12月10日

eventOf

[Pathway:R-HSA-1059683] Interleukin-6 signaling - Homo sapiens

followingEvent

input

isChimeric false

isInDisease false

isInferred false

literatureReference

[LiteratureReference:1067644] Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components
[LiteratureReference:1112500] Janus kinases in interleukin-2-mediated signaling: JAK1 and JAK3 are differentially regulated by tyrosine phosphorylation
[LiteratureReference:1112505] Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130

maxDepth 1

modified [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

name

JAK activation

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-1067659] Assembly of hexameric IL-6 receptor - Homo sapiens

releaseDate 2011年03月15日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:1214159] Rose-John, S, 2011年02月11日

schemaClass BlackBoxEvent

species

[Species:48887] Homo sapiens

stId R-HSA-1112514

summation

[Summation:1112503] The molecular mechanism of Jak activation upon cytokine stim...

Referrals

(precedingEvent)

(hasEvent)

[Pathway:R-HSA-1059683] Interleukin-6 signaling

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