Reactome Pathway Database

Schema > Reaction > Entries

TRAF6 interacts with IRF7 upon TLR7/8 or 9 activation Show undefined attributes

authored

[InstanceEdit:937084] Shamovsky, V, 2010年08月25日

category binding

compartment

created [InstanceEdit:975168] Shamovsky, V, 2010年09月22日

dbId 975188

displayName TRAF6 interacts with IRF7 upon TLR7/8 or 9 activation

edited

[InstanceEdit:1014292] Shamovsky, V, 2010年11月15日

eventOf

[Pathway:R-HSA-975110] TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling - Homo sapiens

followingEvent

input

isChimeric false

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日

name

TRAF6 interacts with IRF7 upon TLR7/8 or 9 activation

output

[Complex:R-HSA-975131] IRF7:TRAF6:p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 [endosome membrane]

precedingEvent

[Reaction:R-HSA-975111] TRAF6 binds to hp- IRAK1/or p-IRAK2:p-IRAK4:MyD88:activated TLR7/8 or 9 - Homo sapiens

relatedSpecies

releaseDate 2010年12月14日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:983288] Gillespie, ME, 2010年10月29日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-975188

summation

[Summation:975120] Upon TLR7/8 or 9 stimulation IRF7, but not IRF3, forms a sig...

Referrals

(hasEvent)

[Pathway:R-HSA-975110] TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling

(precedingEvent)

© 2025 Reactome

Cite Us!