Reactome Pathway Database

Schema > Complex > Entries

pp-IRAK1:p-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 complex [endosome membrane] Show undefined attributes

catalystActivities

[CatalystActivity:975129] protein serine/threonine kinase activity of pp-IRAK1:p-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 complex [endosome membrane]

compartment

[Compartment:74700] endosome membrane

consumedByEvent

[Reaction:R-HSA-975125] Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9 - Homo sapiens

created [InstanceEdit:975168] Shamovsky, V, 2010年09月22日

dbId 975161

displayName pp-IRAK1:p-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 complex [endosome membrane]

hasComponent

inDisease false

literatureReference

[LiteratureReference:975472] Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction

maxDepth 8

modified [InstanceEdit:9768151] Shamovsky, Veronica, 2022年03月04日

name

pp-IRAK1:p-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 complex

producedByEvent

[Reaction:R-HSA-975134] Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9 - Homo sapiens

relatedSpecies

schemaClass Complex

species

[Species:48887] Homo sapiens

stId R-HSA-975161

updateTrackers

Referrals

(updatedInstance)

(output)

[Reaction:R-HSA-975134] Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9

(input)

[Reaction:R-HSA-975125] Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9

(physicalEntity)

[CatalystActivity:975129] protein serine/threonine kinase activity of pp-IRAK1:p-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 complex [endosome membrane]

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