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Go!
Schema
>
EntityWithAccessionedSequence
>
Entries
PLCG1 [cytosol]
Show undefined attributes
Go to Details
compartment
[Compartment:70101] cytosol
componentOf
[Complex:R-HSA-4420203] VEGFA dimer:p-6Y-VEGFR2 dimer:PLCG1 [plasma membrane] - Homo sapiens
[Complex:R-HSA-9665460] p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:PLCG1 [plasma membrane] - Homo sapiens
consumedByEvent
[Reaction:R-HSA-202331] Recruitment of PLC-gamma1 to SLP-76 - Homo sapiens
[Reaction:R-HSA-202212] Recruitment of PLC-gamma1 to LAT - Homo sapiens
[Reaction:R-HSA-4420153] p-6Y-VEGFR2 binds PLCG1 - Homo sapiens
[Reaction:R-HSA-212706] Phospholipase C-gamma1 binds to the activated EGF receptor - Homo sapiens
[Reaction:R-HSA-9665410] Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR bind PLCG1 - Homo sapiens
[Reaction:R-HSA-9665034] Phosphorylated heterodimers of ERBB2 KD mutants and EGFR bind PLCG1 - Homo sapiens
[Reaction:R-HSA-9665706] Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR bind PLCG1 - Homo sapiens
[Reaction:R-HSA-8853755] 2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1 - Homo sapiens
[Reaction:R-HSA-210283] Interaction of PECAM-1 and PLC gamma1 - Homo sapiens
[Reaction:R-HSA-1251944] PLCG1 binds to p-ERBB2:p-EGFR - Homo sapiens
created
[InstanceEdit:202250] Garapati, P V, 2007年10月29日 14:08:25
dbId
202320
displayName
PLCG1 [cytosol]
endCoordinate
1290
inDisease
false
inferredTo
[EntityWithAccessionedSequence:R-MMU-202320] PLCG1 [cytosol] - Mus musculus
[EntityWithAccessionedSequence:R-RNO-202320] PLCG1 [cytosol] - Rattus norvegicus
[EntityWithAccessionedSequence:R-CFA-202320] PLCG1 [cytosol] - Canis familiaris
[EntityWithAccessionedSequence:R-BTA-202320] PLCG1 [cytosol] - Bos taurus
[EntityWithAccessionedSequence:R-SSC-202320] PLCG1 [cytosol] - Sus scrofa
[EntityWithAccessionedSequence:R-DRE-202320] plcg1 [cytosol] - Danio rerio
[EntityWithAccessionedSequence:R-XTR-202320] plcg1 [cytosol] - Xenopus tropicalis
[EntityWithAccessionedSequence:R-GGA-202320] PLCG1 [cytosol] - Gallus gallus
[EntityWithAccessionedSequence:R-DME-202320] sl [cytosol] - Drosophila melanogaster
[EntityWithAccessionedSequence:R-DDI-202320] PLCG1 [cytosol] - Dictyostelium discoideum
[EntityWithAccessionedSequence:R-SPO-202320] PLCG1 [cytosol] - Schizosaccharomyces pombe
[EntityWithAccessionedSequence:R-SCE-202320] PLCG1 [cytosol] - Saccharomyces cerevisiae
[EntityWithAccessionedSequence:R-PFA-202320] PLCG1 [cytosol] - Plasmodium falciparum
maxDepth
1
memberOf
[DefinedSet:R-HSA-1169089] PLC gamma1,2 [cytosol] - Homo sapiens
[CandidateSet:R-HSA-1169379] ISG15 targets [cytosol] - Homo sapiens
modified
[InstanceEdit:5624358] Jupe, Steve, 2014年09月26日
name
PLCG1
Phospholipase C gamma 1
PLC gamma 1
PLC1
referenceEntity
[ReferenceGeneProduct:uniprot:P19174] UniProt:P19174 PLCG1
referenceType
ReferenceGeneProduct
schemaClass
EntityWithAccessionedSequence
species
[Species:48887] Homo sapiens
stId
R-HSA-202320
startCoordinate
2
updateTrackers
[UpdateTracker:9883870] Update Tracker - [EntityWithAccessionedSequence:202320] PLCG1 [cytosol] - v45:[addName]
[UpdateTracker:9870307] Update Tracker - [EntityWithAccessionedSequence:202320] PLCG1 [cytosol] - v38:[addName]
[UpdateTracker:9888165] Update Tracker - [EntityWithAccessionedSequence:202320] PLCG1 [cytosol] - v46:[removeName]
[UpdateTracker:9870979] Update Tracker - [EntityWithAccessionedSequence:202320] PLCG1 [cytosol] - v39:[addName, modifyStartCoordinate]
Referrals
(updatedInstance)
[UpdateTracker:9883870] Update Tracker - [EntityWithAccessionedSequence:202320] PLCG1 [cytosol] - v45:[addName]
[UpdateTracker:9870307] Update Tracker - [EntityWithAccessionedSequence:202320] PLCG1 [cytosol] - v38:[addName]
[UpdateTracker:9888165] Update Tracker - [EntityWithAccessionedSequence:202320] PLCG1 [cytosol] - v46:[removeName]
[UpdateTracker:9870979] Update Tracker - [EntityWithAccessionedSequence:202320] PLCG1 [cytosol] - v39:[addName, modifyStartCoordinate]
(input)
[Reaction:R-HSA-9665410] Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR bind PLCG1
[Reaction:R-HSA-9665034] Phosphorylated heterodimers of ERBB2 KD mutants and EGFR bind PLCG1
[Reaction:R-HSA-9665706] Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR bind PLCG1
[Reaction:R-HSA-8853755] 2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1
[Reaction:R-HSA-210283] Interaction of PECAM-1 and PLC gamma1
[Reaction:R-HSA-202331] Recruitment of PLC-gamma1 to SLP-76
[Reaction:R-HSA-202212] Recruitment of PLC-gamma1 to LAT
[Reaction:R-HSA-4420153] p-6Y-VEGFR2 binds PLCG1
[Reaction:R-HSA-1251944] PLCG1 binds to p-ERBB2:p-EGFR
[Reaction:R-HSA-212706] Phospholipase C-gamma1 binds to the activated EGF receptor
(hasComponent)
[Complex:R-HSA-9665460] p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:PLCG1 [plasma membrane]
[Complex:R-HSA-9665033] p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR:PLCG1 [plasma membrane]
[Complex:R-HSA-9665924] p-6Y-ERBB2 R678Q:EGF:p-6Y-EGFR:PLCG1 [plasma membrane]
[Complex:R-HSA-8854776] 2x p-5Y-RET:GDNF:GFRA complexes:PLCG1 [plasma membrane]
[Complex:R-HSA-210240] PECAM-1:PLC gamma1 complex [plasma membrane]
[Complex:R-HSA-202279] PLCG1:p-3Y-SLP-76:Gads:LAT [plasma membrane]
[Complex:R-HSA-202240] PLCG1:p-5Y-LAT [plasma membrane]
[Complex:R-HSA-4420203] VEGFA dimer:p-6Y-VEGFR2 dimer:PLCG1 [plasma membrane]
[Complex:R-HSA-1251942] EGF:p-EGFR:p-ERBB2:PLCG1 [plasma membrane]
[Complex:R-HSA-212717] EGF-like ligands:p-6Y-EGFR:PLCG1 [plasma membrane]
(hasMember)
[CandidateSet:R-HSA-1169379] ISG15 targets [cytosol]
[DefinedSet:R-HSA-1169089] PLC gamma1,2 [cytosol]
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