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Schema
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Reaction
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Entries
PC is hydrolyzed to 2-acyl LPC by PLA2G4C
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authored
[InstanceEdit:1602345] Williams, MG, 2011年09月14日
catalystActivity
[CatalystActivity:1524121] phospholipase A1 activity of PLA2G4C [endoplasmic reticulum membrane]
category
transition
compartment
[Compartment:12045] endoplasmic reticulum membrane
[Compartment:70101] cytosol
created
[InstanceEdit:1482800] Williams, MG, 2011年08月12日
dbId
1482827
displayName
PC is hydrolyzed to 2-acyl LPC by PLA2G4C
edited
[InstanceEdit:1482514] Williams, MG, 2011年08月12日
eventOf
[Pathway:R-HSA-1482788] Acyl chain remodelling of PC - Homo sapiens
followingEvent
[Reaction:R-HSA-1482533] 2-acyl LPC is acylated to PC by LPCAT - Homo sapiens
[Reaction:R-HSA-1482629] 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C - Homo sapiens
[Reaction:R-HSA-1482612] 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] - Homo sapiens
input
[SimpleEntity:R-ALL-29356] H2O [cytosol]
[SimpleEntity:R-ALL-426925] PC [endoplasmic reticulum membrane]
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:1482664] Interfacial kinetic and binding properties of mammalian group IVB phospholipase A2 (cPLA2beta) and comparison with the other cPLA2 isoforms
[LiteratureReference:1482631] Subcellular localization and lysophospholipase/transacylation activities of human group IVC phospholipase A2 (cPLA2gamma)
[LiteratureReference:1482624] Roles of C-terminal processing, and involvement in transacylation reaction of human group IVC phospholipase A2 (cPLA2gamma)
maxDepth
1
modified
[InstanceEdit:11033291] Weiser, Joel, 2025年08月28日
name
PC is hydrolyzed to 2-acyl LPC by PLA2G4C
orthologousEvent
[Reaction:R-RNO-1482827] PC is hydrolyzed to 2-acyl LPC by PLA2G4C - Rattus norvegicus
[Reaction:R-SCE-1482827] PC is hydrolyzed to 2-acyl LPC by PLA2G4C - Saccharomyces cerevisiae
[Reaction:R-SPO-1482827] PC is hydrolyzed to 2-acyl LPC by PLA2G4C - Schizosaccharomyces pombe
[Reaction:R-DRE-1482827] PC is hydrolyzed to 2-acyl LPC by PLA2G4C - Danio rerio
[Reaction:R-MMU-1482827] PC is hydrolyzed to 2-acyl LPC by PLA2G4C - Mus musculus
output
[SimpleEntity:R-ALL-975614] 2-acyl LPC [endoplasmic reticulum membrane]
[SimpleEntity:R-ALL-1524021] LCFA(-) [endoplasmic reticulum membrane]
precedingEvent
[Reaction:R-HSA-1483219] PC is exchanged with PI by PITPNB - Homo sapiens
[Reaction:R-HSA-1482533] 2-acyl LPC is acylated to PC by LPCAT - Homo sapiens
[Reaction:R-HSA-1482961] CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane - Homo sapiens
[Reaction:R-HSA-1482547] 1-acyl LPC is acylated to PC by LPCAT - Homo sapiens
releaseDate
2012年06月12日
reviewStatus
[ReviewStatus:9821382] five stars
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-1482827
summation
[Summation:1482891] At the endoplasmic reticulum (ER) membrane, phosphatidylchol...
Referrals
(hasEvent)
[Pathway:R-HSA-1482788] Acyl chain remodelling of PC
(precedingEvent)
[Reaction:R-HSA-1482533] 2-acyl LPC is acylated to PC by LPCAT
[Reaction:R-HSA-1482629] 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C
[Reaction:R-HSA-1482612] 2-acyl LPC is hydrolyzed to GPCho by PLA2[8]
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