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Schema
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Entries
2-acyl LPC is hydrolyzed to GPCho by PLA2[8]
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authored
[InstanceEdit:1602345] Williams, MG, 2011年09月14日
catalystActivity
[CatalystActivity:1524022] phosphatidylcholine lysophospholipase activity of PLA2(8) [cytosol]
category
transition
compartment
[Compartment:12045] endoplasmic reticulum membrane
[Compartment:70101] cytosol
created
[InstanceEdit:1482525] Williams, MG, 2011年08月12日
dbId
1482612
displayName
2-acyl LPC is hydrolyzed to GPCho by PLA2[8]
edited
[InstanceEdit:1482514] Williams, MG, 2011年08月12日
eventOf
[Pathway:R-HSA-1483115] Hydrolysis of LPC - Homo sapiens
followingEvent
[Reaction:R-HSA-1483116] GPCho is hydrolyzed to Cho and G3P by GPCPD1 - Homo sapiens
input
[SimpleEntity:R-ALL-975614] 2-acyl LPC [endoplasmic reticulum membrane]
[SimpleEntity:R-ALL-29356] H2O [cytosol]
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:1482693] The identification of a phospholipase B precursor in human neutrophils
[LiteratureReference:1482664] Interfacial kinetic and binding properties of mammalian group IVB phospholipase A2 (cPLA2beta) and comparison with the other cPLA2 isoforms
[LiteratureReference:1482518] Serine 228 is essential for catalytic activities of 85-kDa cytosolic phospholipase A2
[LiteratureReference:1482631] Subcellular localization and lysophospholipase/transacylation activities of human group IVC phospholipase A2 (cPLA2gamma)
[LiteratureReference:1482624] Roles of C-terminal processing, and involvement in transacylation reaction of human group IVC phospholipase A2 (cPLA2gamma)
maxDepth
1
modified
[InstanceEdit:11033291] Weiser, Joel, 2025年08月28日
name
2-acyl LPC is hydrolyzed to GPCho by PLA2[8]
orthologousEvent
[Reaction:R-SCE-1482612] 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] - Saccharomyces cerevisiae
[Reaction:R-SPO-1482612] 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] - Schizosaccharomyces pombe
[Reaction:R-DDI-1482612] 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] - Dictyostelium discoideum
[Reaction:R-GGA-1482612] 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] - Gallus gallus
[Reaction:R-XTR-1482612] 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] - Xenopus tropicalis
[Reaction:R-DRE-1482612] 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] - Danio rerio
[Reaction:R-SSC-1482612] 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] - Sus scrofa
[Reaction:R-BTA-1482612] 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] - Bos taurus
[Reaction:R-CFA-1482612] 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] - Canis familiaris
[Reaction:R-RNO-1482612] 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] - Rattus norvegicus
[Reaction:R-MMU-1482612] 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] - Mus musculus
output
[SimpleEntity:R-ALL-1498750] GPCho [cytosol]
[SimpleEntity:R-ALL-1524021] LCFA(-) [endoplasmic reticulum membrane]
precedingEvent
[Reaction:R-HSA-1482862] PC is hydrolysed to 2-acyl LPC by PLA2[7] - Homo sapiens
[Reaction:R-HSA-1482827] PC is hydrolyzed to 2-acyl LPC by PLA2G4C - Homo sapiens
releaseDate
2012年06月12日
reviewStatus
[ReviewStatus:9821382] five stars
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-1482612
summation
[Summation:1482535] At the endoplasmic reticulum (ER) membrane, 2-acyl lysophosp...
Referrals
(hasEvent)
[Pathway:R-HSA-1483115] Hydrolysis of LPC
(precedingEvent)
[Reaction:R-HSA-1483116] GPCho is hydrolyzed to Cho and G3P by GPCPD1
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