ARPKD and the liver

The severity of liver problems in autosomal recessive polycystic kidney disease (ARPKD) can vary from mild impairment to serious complications that can be life-threatening.

For most children with ARPKD, their liver continues to function well. But cysts, infections, fibrosis and other complications can cause a range of symptoms.

Consultant paediatric hepatologist Dr Tassos Grammatikopoulos, King's College Hospital London, explains the impact on the liver of ARPKD.