BIDN

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BIDN
Names

IUPAC name 3,3-Bis(trifluoromethyl)bicyclo[2.2.1]heptane-2,2-dicarbonitrile
Other names Flucybene
Identifiers
CAS Number	82947-63-5 ^checkY[EPA]
3D model (JSmol)	Interactive image
ChemSpider	118266
PubChem CID	134125
CompTox Dashboard (EPA)	DTXSID501003018 Edit this at Wikidata
InChI InChI=1S/C11H8F6N2/c12-10(13,14)9(11(15,16)17)7-2-1-6(3-7)8(9,4-18)5-19/h6-7H,1-3H2 Key: MUIBMWREADMFQF-UHFFFAOYSA-N
SMILES C1CC2CC1C(C2(C(F)(F)F)C(F)(F)F)(C#N)C#N
Properties
Chemical formula	C₁₁H₈F₆N₂
Molar mass	282.189 g·mol⁻¹
Hazards
GHS labelling:
Pictograms	GHS06: Toxic
Signal word	Danger
Hazard statements	H300
Precautionary statements	P264, P270, P301+P310, P321, P330, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Chemical compound

BIDN is a GABA receptor antagonist and convulsant.^[1]

References

^ Rauh, James J; Holyoke, Caleb W; Kleier, Daniel A; Presnail, James K; Benner, Eric A; Cordova, Daniel; Howard, Michael H; Hosie, Alastair M; Buckingham, Steven D; Baylis, Howard A; Sattelle, David B (1997). "Polycyclic dinitriles: a novel class of potent GABAergic insecticides provides a new radioligand, [3H]BIDN". Invertebrate Neuroscience. 3 (2–3): 261–8. doi:10.1007/bf02480383. PMID 9783448. S2CID 33478021.

GABA_A Tooltip γ-Aminobutyric acid A receptor

GABA_A-ρ Tooltip γ-Aminobutyric acid A-rho receptor

GABA_B Tooltip γ-Aminobutyric acid B receptor

See also: Receptor/signaling modulators; GABA_A receptor positive modulators; GABA metabolism/transport modulators

v t e Convulsants
GABA receptor antagonists	Bicuculline Bicyclic phosphates (TBPS, TBPO, IPTBO) BIDN Chlorophenylsilatrane Cicutoxin Cloflubicyne Coriamyrtin Dihydropicrotoxinin DMCM EBOB Endosulfan FG-7142 Fipronil Flurothyl Gabazine Oenanthotoxin Pentylenetetrazol Phenylsilatrane Picrotoxin p-CN-TBOB p-NCS-TBOB RDX TBOB Tetramethylenedisulfotetramine Thujone Trimethylolpropane phosphite Tutin
GABA synthesis inhibitors	3-Mercaptopropionic acid 4-Deoxypyridoxine Allylglycine Crimidine Decaborane Ginkgotoxin Isoniazid Pentaborane Thiocarbohydrazide Toxopyrimidine
Glycine receptor antagonists	Coriamyrtin Dendrobine Picrotoxin Strychnine Tutin
Glutamate receptor agonists	AMPA Domoic acid Kainic acid NMDA Quisqualic acid Tetrazolylglycine
Convulsant barbiturates	CHEB Diberal (DMBB) McN-481
Other	2,2,3,3-Tetrafluoropropyl trifluoromethyl ether Bromocamphor Camphor FAZ-4 Fluoroethyl fluoroacetate MC-2973 Methionine sulfoximine Methyl fluoroacetate Nitrocyclohexane Thebaine

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