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Toxopyrimidine

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Toxopyrimidine
Names
Preferred IUPAC name
(4-Amino-2-methylpyrimidin-5-yl)methanol
Other names
Pyramin[1]
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.234.283 Edit this at Wikidata
UNII
  • InChI=1S/C6H9N3O/c1-4-8-2-5(3-10)6(7)9-4/h2,10H,3H2,1H3,(H2,7,8,9)
    Key: VUTBELPREDJDDH-UHFFFAOYSA-N
  • Cc1ncc(c(n1)N)CO
Properties
C6H9N3O
Molar mass 139.158 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Chemical compound

Toxopyrimidine is a vitamin B6 antagonist with potent convulsant effects.[2] [3]

See also

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References

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  1. ^ Haughton BG, King HK (December 1958). "Toxo-pyrimidine phosphate as an inhibitor of bacterial enzyme systems that require pyridoxal phosphate". The Biochemical Journal. 70 (4): 660–5. doi:10.1042/bj0700660. PMC 1196724 . PMID 13607425.
  2. ^ Rindi G, Ferrari G (February 1959). "The gamma-aminobutyric acid and glutamic acid content of brains of rats treated with toxopyrimidine". Nature. 183 (4661): 608–9. Bibcode:1959Natur.183..608R. doi:10.1038/183608a0. PMID 13632808. S2CID 4200644.
  3. ^ Rindi G, Perri V, Ventura U (April 1959). "Effect of toxopyrimidine on glutamic-decarboxylase and glutamic-oxalacetic transaminase of rat brain". Nature. 183 (4668): 1126–7. Bibcode:1959Natur.183.1126R. doi:10.1038/1831126a0. PMID 13657025. S2CID 4209134.
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Animal toxins
Bacterial
Cyanotoxins
Plant toxins
Mycotoxins
Pesticides
Nerve agents
Bicyclic phosphates
Cholinergic neurotoxins
Psychoactive drugs
Other
GABA receptor antagonists
GABA synthesis inhibitors
Glycine receptor antagonists
Glutamate receptor agonists
Convulsant barbiturates
Other


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