SLC12A8

Identifiants

Alias

IDs externes

OMIM: 611316 MGI: 2443672 HomoloGene: 11628 GeneCards: SLC12A8

Position du gène (humain)
Chromosome 3 humain
Chr.	Chromosome 3 humain ^[1]
Chromosome 3 humain Localisation génomique pour SLC12A8 Localisation génomique pour SLC12A8
Locus	3q21.2	Début	125,082,636 bp ^[1]
Locus	3q21.2	Fin	125,212,864 bp ^[1]

Position du gène (souris)
Chromosome 16 (souris)
Chr.	Chromosome 16 (souris)^[2]
Chromosome 16 (souris) Localisation génomique pour SLC12A8 Localisation génomique pour SLC12A8
Locus	16\|16 B3	Début	33,337,698 bp ^[2]
Locus	16\|16 B3	Fin	33,484,505 bp ^[2]

Expression génique

Bgee

Humain	Souris (orthologue)
Fortement exprimé dans right lobe of thyroid gland left lobe of thyroid gland ovocyte parotide ligament alvéolo-dentaire vésicule biliaire Caduque basale secondary oocyte body of pancreas pancreatic ductal cell	Fortement exprimé dans gastrula glande submandibulaire parotide crypt of lieberkuhn of small intestine duodénum gros intestin côlon antre du pylore iléon Jéjunum
Plus de données d'expression de référence

BioGPS

n/a

Gene Ontology
Fonction moléculaire	symporter activity potassium:chloride symporter activity
Composant cellulaire	integral component of membrane membrane
Processus biologique	potassium ion transport ion transport transport transmembranaire potassium ion transmembrane transport cell volume homeostasis chloride ion homeostasis potassium ion homeostasis chloride transmembrane transport potassium ion import across plasma membrane
Sources:Amigo / QuickGO

Orthologues

Espèces

Homme

Souris

Entrez


84561


171286

Ensembl


ENSG00000221955


ENSMUSG00000035506

UniProt


A0AV02 H7C5L2


Q8VI23

RefSeq (mRNA)

NM_024628
NM_001195483

NM_001083902
NM_134251
NM_001370999

RefSeq (protéine)

NP_001182412
NP_078904

NP_001077371
NP_599012
NP_001357928

Localisation (UCSC)

Chr 3: 125.08 – 125.21 Mb

Chr 16: 33.34 – 33.48 Mb

Publication PubMed

^[3]

^[4]

Wikidata

Voir/Editer Humain Voir/Editer Souris

SLC12A8 est un gène situé sur le chromosome 3 humain ^[5].

Maladies liées

[modifier | modifier le code ]

Psoriasis ^[6]

Notes et références

[modifier | modifier le code ]

↑ ^{a b et c} GRCh38: Ensembl release 89: ENSG00000221955 - Ensembl, May 2017
↑ ^{a b et c} GRCm38: Ensembl release 89: ENSMUSG00000035506 - Ensembl, May 2017
↑ « Publications PubMed pour l'Homme », sur National Center for Biotechnology Information, U.S. National Library of Medicine
↑ « Publications PubMed pour la Souris », sur National Center for Biotechnology Information, U.S. National Library of Medicine
↑ « Human Gene SLC12A8 (ENST00000931093.1) from GENCODE V49 », sur genome.ucsc.edu (consulté le 30 mai 2026)
↑ (en) GeneCards Human Gene Database, « SLC12A8 Gene - GeneCards | S12A8 Protein | S12A8 Antibody » [archive du 14 août 2025], sur www.genecards.org (consulté le 30 mai 2026)

v · m Chromosome 3 humain
Gènes	ACKR2 ACKR4 ADGRG7 AGTR1 ARHGAP31 ATP13A5 CASR CCR1 CCR2 CCR3 CCR4 CCR5 CCR8 CCR9 CCRL2 CELSR3 CNBP COL7A1 COL8A1 CX3CR1 CXCR6 DRD3 EDNRB GHSR GPR149 GPR156 GPR15 GPR160 GPR171 GPR27 GPR62 GPR87 GRM2 GRM7 Gène klotho HRH1 HTR1F KPNA1 NEPRO OR5AC1 OR5AC2 OR5H14 OR5H15 OR5H1 OR5H2 OR5H6 OR5H8 OR5K1 OR5K2 OR5K3 OR5K4 OXTR P2RY12 P2RY13 P2RY14 P2RY1 PTH1R RHO SLC12A8 SLC15A2 SLC22A13 SLC22A14 SLC25A1 SLC25A20 SLC25A26 SLC25A36 SLC25A38 SLC26A6 SLC2A2 SLC33A1 SLC35A5 SLC35G2 SLC38A3 SLC41A3 SLC49A4 SLC4A7 SLC51A SLC6A11 SLC6A1 SLC6A20 SLC6A6 SLC7A14 SLC9A9 SLC9C1 SLCO2A1 SOX2 SUCNR1 TPRA1 VIPR1 XCR1
Protéines	Acétyl-CoA-C-acyltransférase Butyrylcholinestérase Déshydrogénase d'acyl-coenzyme A GLUT2 Hexokinase Importine alpha Isomérase de ribose-5-phosphate Kinase de pyruvate-déshydrogénase Malate-déshydrogénase Protéine trifonctionnelle mitochondriale Pyruvate-déshydrogénase Succinyl-coenzyme A-synthétase Thyroperoxydase Titine TMEM43 Ubiquitine
Maladies liées	Acéruléoplasminémie Alcaptonurie Atrophie optique type I Cavernome cérébral héréditaire Chondrodysplasie métaphysaire type Jansen Démence frontotemporale par mutation du gène CHMP2B Déficience en sucrase-isomaltase Dysplasie anauxétique Dysplasie septo-optique Dystrophie musculaire des ceintures Déficit en biotinidase Encéphalopathie glycinique Épidermolyse bulleuse dystrophique Maladie de Charcot-Marie-Tooth type 2 Maladie génétique du métabolisme des nucléotides Maladie de von Hippel-Lindau Microcéphalie primaire autosomique récessive Myopathie métabolique Myopathie myotonique proximale Myopathie à némaline Pathologies oculaires par mutation du gène SOX2 Porphyrie Syndrome de Bardet-Biedl Syndrome de Brugada Syndrome de Kallmann Syndrome de Larsen Syndrome de microdélétion 3q29 Syndrome des plaquettes grises Syndrome de Romano-Ward Syndrome de Goldston Syndrome EEC

v · m

Gènes codant les transporteurs de solutés

SLC1 à SLC10

SLC1	SLC1A1 SLC1A2 SLC1A3 SLC1A4 SLC1A5 SLC1A6 SLC1A7
SLC2	SLC2A1 SLC2A2 SLC2A3 SLC2A4 SLC2A5 SLC2A6 SLC2A7 SLC2A8 SLC2A9 SLC2A10 SLC2A11 SLC2A12 SLC2A13 SLC2A14
SLC3	SLC3A1 SLC3A2
SLC4	SLC4A1 SLC4A2 SLC4A3 SLC4A4 SLC4A5 SLC4A6 SLC4A7 SLC4A8 SLC4A9 SLC4A10 SLC4A11
SLC5	SLC5A1 SLC5A2 SLC5A3 SLC5A4 SLC5A5 SLC5A6 SLC5A7 SLC5A8 SLC5A9 SLC5A10 SLC5A11 SLC5A12
SLC6	SLC6A1 SLC6A2 SLC6A3 SLC6A4 SLC6A5 SLC6A6 SLC6A7 SLC6A8 SLC6A9 SLC6A10 SLC6A11 SLC6A12 SLC6A13 SLC6A14 SLC6A15 SLC6A16 SLC6A17 SLC6A18 SLC6A19 SLC6A20
SLC7	SLC7A1 SLC7A2 SLC7A3 SLC7A4 SLC7A5 SLC7A6 SLC7A7 SLC7A8 SLC7A9 SLC7A10 SLC7A11 SLC7A12 SLC7A13 SLC7A14
SLC8	SLC8A1 SLC8A2 SLC8A3
SLC9	SLC9A1 SLC9A2 SLC9A3 SLC9A4 SLC9A5 SLC9A6 SLC9A7 SLC9A8 SLC9A9 SLC9B1 SLC9B2 SLC9C1 SLC9C2
SLC10	SLC10A1 SLC10A2 SLC10A3 SLC10A4 SLC10A5 SLC10A6 SLC10A7

SLC11 à SLC20

SLC11	SLC11A1 SLC11A2
SLC12	SLC12A1 SLC12A2 SLC12A3 SLC12A4 SLC12A5 SLC12A6 SLC12A7 SLC12A8 SLC12A9
SLC13	SLC13A1 SLC13A2 SLC13A3 SLC13A4 SLC13A5
SLC14	SLC14A1 SLC14A2
SLC15	SLC15A1 SLC15A2 SLC15A3 SLC15A4
SLC16	SLC16A1 SLC16A2 SLC16A3 SLC16A4 SLC16A5 SLC16A6 SLC16A7 SLC16A8 SLC16A9 SLC16A10 SLC16A11 SLC16A12 SLC16A13 SLC16A14
SLC17	SLC17A1 SLC17A2 SLC17A3 SLC17A4 SLC17A5 SLC17A6 SLC17A7 SLC17A8 SLC17A9
SLC18	SLC18A1 SLC18A2 SLC18A3 SLC18B1
SLC19	SLC19A1 SLC19A2 SLC19A3
SLC20	SLC20A1 SLC20A2

SLC21 à SLC30

SLC22	SLC22A1 SLC22A2 SLC22A3 SLC22A4 SLC22A5 SLC22A6 SLC22A7 SLC22A8 SLC22A9 SLC22A10 SLC22A11 SLC22A12 SLC22A13 SLC22A14 SLC22A15 SLC22A16 SLC22A17 SLC22A18 SLC22A20 SLC22A21 SLC22A22 SLC22A23 SLC22A24 SLC22A25 SLC22A31 MFSD10 SV2A SV2B SV2C SVOP SVOPL
SLC23	SLC23A1 SLC23A2 SLC23A3 SLC23A4
SLC24	SLC24A1 SLC24A2 SLC24A3 SLC24A4 SLC24A5
SLC25	SLC25A1 SLC25A2 SLC25A3 SLC25A4 SLC25A5 SLC25A6 UCP1 UCP2 UCP3 SLC25A10 SLC25A11 SLC25A12 SLC25A13 SLC25A14 SLC25A15 SLC25A16 SLC25A17 SLC25A18 SLC25A19 SLC25A20 SLC25A21 SLC25A22 SLC25A23 SLC25A24 SLC25A25 SLC25A26 SLC25A27 SLC25A28 SLC25A29 SLC25A30 SLC25A31 SLC25A32 SLC25A33 SLC25A34 SLC25A35 SLC25A36 SLC25A37 SLC25A38 SLC25A39 SLC25A40 SLC25A41 SLC25A42 SLC25A43 SLC25A44 SLC25A45 SLC25A46 SLC25A47 SLC25A48 MTCH1 MTCH2 SLC25A51 SLC25A52 SLC25A53
SLC26	SLC26A1 SLC26A2 SLC26A3 SLC26A4 SLC26A5 SLC26A6 SLC26A7 SLC26A8 SLC26A9 SLC26A10 SLC26A11
SLC27	SLC27A1 SLC27A2 SLC27A3 SLC27A4 SLC27A5 SLC27A6
SLC28	SLC28A1 SLC28A2 SLC28A3
SLC29	SLC29A1 SLC29A2 SLC29A3 SLC29A4
SLC30	SLC30A1 SLC30A2 SLC30A3 SLC30A4 SLC30A5 SLC30A6 SLC30A7 SLC30A8 SLC30A9 SLC30A10

SLC31 à SLC40

SLC31	SLC31A1 SLC31A2
SLC32	SLC32A1
SLC33	SLC33A1 MFSD3
SLC34	SLC34A1 SLC34A2 SLC34A3
SLC35	SLC35A1 SLC35A2 SLC35A3 SLC35A4 SLC35A5 SLC35B1 SLC35B2 SLC35B3 SLC35B4 SLC35C1 SLC35C2 SLC35D1 SLC35D2 SLC35D3 SLC35E1 SLC35E2 SLC35E3 SLC35E4 SLC35F1 SLC35F2 SLC35F3 SLC35F4 SLC35F5 SLC35F6 SLC35G1 SLC35G2 SLC35G3 SLC35G4 SLC35G5 SLC35G6 TMEM241
SLC36	SLC36A1 SLC36A2 SLC36A3 SLC36A4
SLC37	SLC37A1 SLC37A2 SLC37A3 SLC37A4
SLC38	SLC38A1 SLC38A2 SLC38A3 SLC38A4 SLC38A5 SLC38A6 SLC38A7 SLC38A8 SLC38A9 SLC38A10
SLC39	SLC39A1 SLC39A2 SLC39A3 SLC39A4 SLC39A5 SLC39A6 SLC39A7 SLC39A8 SLC39A9 SLC39A10 SLC39A11 SLC39A12 SLC39A13 SLC39A14
SLC40	SLC40A1

SLC41 à SLC50

SLC41	SLC41A1 SLC41A2 SLC41A3
SLC42	RhAG RhBG RhCG
SLC43	SLC43A1 SLC43A2 SLC43A3
SLC44	SLC44A1 SLC44A2 SLC44A3 SLC44A4 SLC44A5
SLC45	SLC45A1 SLC45A2 SLC45A3 SLC45A4
SLC46	SLC46A1 SLC46A2 SLC46A3
SLC47	SLC47A1 SLC47A2
SLC48	SLC48A1
SLC49	FLVCR2 SLC49A3 SLC49A4
SLC50	SLC50A1

SLC51 à SLC60

SLC51	SLC51A SLC51B
SLC52	SLC52A1 SLC52A2 SLC52A3
SLC53	XPR1
SLC54	MPC1 MPC2 MPC1L
SLC55	LETM1 LETM2 LETM3
SLC56	SFXN1 SFXN2 SFXN3 SFXN4 SFXN5
SLC57	NIPA1 NIPA2 NIPAL1 NIPAL2 NIPAL3 NIPAL4
SLC58	MAGT1 TUSC3
SLC59	MFSD2A MFSD2B
SLC60	MFSD4A MFSD4B

SLC61 à SLC70

SLC61	MFSD5
SLC62	ANKH
SLC63	SPNS1 SPNS2 SPNS3
SLC64	TMEM165
SLC65	NPC1 NPC1L1 PTCH1 PTCH2 PTCHD1
SLC66	CTNS MPDU1
SLC67	SLC67A1 SLC67A2
SLC68	SLC68A1 SLC68A2P
SLC69	STRA6
SLC70	CNNM1 CNNM2 CNNM3 CNNM4

SLC71 à SLC76

SLC71	SLC71A1 SLC71A2 SLC71A3P
SLC72	MFSD1
SLC73	MFSD6 MFSD6L
SLC74	MFSD8
SLC75	SLC75A1
SLC76	RFT1

Ce document provient de « https://fr.wikipedia.org/w/index.php?title=SLC12A8&oldid=236645588 ».