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PGRMC2

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
PGRMC2
Identifiers
Aliases PGRMC2 , DG6, PMBP, progesterone receptor membrane component 2
External IDsOMIM: 607735; MGI: 1918054; HomoloGene: 38169; GeneCards: PGRMC2; OMA:PGRMC2 - orthologs
Gene location (Human)
Chromosome 4 (human)
Chr. Chromosome 4 (human) [1]
Band 4q28.2Start128,269,237 bp [1]
End128,288,829 bp [1]
Gene location (Mouse)
Chromosome 3 (mouse)
Chr. Chromosome 3 (mouse)[2]
Band 3|3 BStart41,020,761 bp [2]
End41,037,481 bp [2]
RNA expression pattern
Bgee
Human Mouse (ortholog)
  • jejunal mucosa

  • islet of Langerhans

  • stromal cell of endometrium

  • epithelium of colon

  • skin of abdomen

  • skin of arm

  • skin of leg

  • adipose tissue

  • rectum

  • abdominal fat
  • otic placode

  • saccule

  • supraoptic nucleus

  • otic vesicle

  • motor neuron

  • yolk sac

  • skin of external ear

  • Epithelium of choroid plexus

  • seminal vesicula

  • decidua
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

10424

70804

Ensembl

ENSG00000164040

ENSMUSG00000049940

UniProt

O15173

Q80UU9

RefSeq (mRNA)

NM_006320

NM_027558

RefSeq (protein)

NP_006311

NP_081834

Location (UCSC)Chr 4: 128.27 – 128.29 Mb Chr 3: 41.02 – 41.04 Mb
PubMed search[3] [4]
Wikidata

Progesterone receptor membrane component 2 (abbreviated PGRMC2) is a protein which is encoded by the PGRMC2 gene.[5] [6] It has been detected in the placenta, liver, and spermatozoa, among other areas.[5] [6]

See also

[edit ]

References

[edit ]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000164040Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000049940Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b Gerdes D, Wehling M, Leube B, Falkenstein E (1998). "Cloning and tissue expression of two putative steroid membrane receptors". Biol. Chem. 379 (7): 907–11. doi:10.1515/bchm.1998.379.7.907. PMID 9705155.
  6. ^ a b Lösel R, Breiter S, Seyfert M, Wehling M, Falkenstein E (2005). "Classic and non-classic progesterone receptors are both expressed in human spermatozoa". Horm. Metab. Res. 37 (1): 10–4. doi:10.1055/s-2005-861023. PMID 15702432.
PR Tooltip Progesterone receptor
Agonists
Mixed
(SPRMs Tooltip Selective progesterone receptor modulators)
Antagonists
mPR Tooltip Membrane progesterone receptor
(PAQR Tooltip Progestin and adipoQ receptor)
Agonists
Antagonists


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