A significant association was identified between transsexualism and the AR allele, with transsexuals having longer AR repeat lengths than non-transsexual male control subjects (p = .04). No associations for transsexualism were evident in repeat lengths for CYP19 or ERβ genes. Individuals were then classified as short or long for each gene polymorphism on the basis of control median polymorphism lengths in order to further elucidate possible combined effects. No interaction associations between the three genes and transsexualism were identified.
Conclusions
This study provides evidence that male gender identity might be partly mediated through the androgen receptor.
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Posté par Mouns . En réponse au journal Defier la loi du genre. Évalué à 2.
A significant association was identified between transsexualism and the AR allele, with transsexuals having longer AR repeat lengths than non-transsexual male control subjects (p = .04). No associations for transsexualism were evident in repeat lengths for CYP19 or ERβ genes. Individuals were then classified as short or long for each gene polymorphism on the basis of control median polymorphism lengths in order to further elucidate possible combined effects. No interaction associations between the three genes and transsexualism were identified.
Conclusions
This study provides evidence that male gender identity might be partly mediated through the androgen receptor.
source :
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi(...)