Abstract:Virulence of the fungal human pathogen Candida albicans is also attributed to its ability to switch reversibly between yeast and hyphal growth forms. Morphogenesis in this yeast is influenced by the composition of the environment, activating sensors, which consequently play an important role in fungal pathogenicity. This review summarizes some of the main environmental sensors, their ligands and downstream signaling pathways in C. albicans. We will focus on proteins localized in the plasma membrane and on the interaction between cells and their environment. This will underline the convergence of several environmental signals onto the mitogen-activated protein kinase and protein kinase A pathways.

Status: Published Type: Journal Article|Research Support, Non-U.S. Gov't PubMed ID: 19473245

Jump to Summary Chart for:

#1-10(ACE2-CZF1) #11-20(EFG1-HGT4) #21-30(HGT7-MSB2) #31-40(NCE103-STE4) #41-43(STP1-TUP1)

• To find other papers on a gene and topic, click on the colored ball in the appropriate box.
  displays other papers with information about that topic for that gene.
  displays other papers in CGD that are associated with that topic.
  The topic is addressed in these papers but does not describe a specific gene or chromosomal feature.


• To go to the Locus page for a gene, click on the gene name.

Jump to Summary Chart for:

#1-10(ACE2-CZF1) #11-20(EFG1-HGT4) #21-30(HGT7-MSB2) #31-40(NCE103-STE4) #41-43(STP1-TUP1)

• To find other papers on a gene and topic, click on the colored ball in the appropriate box.
  displays other papers with information about that topic for that gene.
  displays other papers in CGD that are associated with that topic.
  The topic is addressed in these papers but does not describe a specific gene or chromosomal feature.


• To go to the Locus page for a gene, click on the gene name.