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Lopes JP, Lionakis MS (2022) Pathogenesis and virulence of Candida albicans Virulence 13:89-121
Pubmed Entry


Abstract:Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic immunosuppression, and/or medical interventions that impair the integrity of the mucocutaneous barrier and/or perturb protective host defense mechanisms enable C. albicans to become an opportunistic pathogen and cause debilitating mucocutaneous disease and/or life-threatening systemic infections. In this review, we synthesize our current knowledge of the tissue-specific determinants of C. albicans pathogenicity and host immune defense mechanisms.
Status: Published Type: Review PubMed ID: 34964702

Topics addressed in this paper
There are 44 different genes addressed in this paper.

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Topics
Genes linked to topics(#1-10)
ALA1
(C. albicans)		ALS1
(C. albicans)		ALS3
(C. albicans)		BCR1
(C. albicans)		CCH1
(C. albicans)		CDR1
(C. albicans)		CDR2
(C. albicans)		CPH1
(C. albicans)		CRZ1
(C. albicans)		CSA1
(C. albicans)
Candida albicans
Reviews

Topics
Genes linked to topics(#11-20)
CSA2
(C. albicans)		CTA1
(C. albicans)		CZF1
(C. albicans)		DFG16
(C. albicans)		ECE1
(C. albicans)		EFG1
(C. albicans)		ERG11
(C. albicans)		ERG3
(C. albicans)		ERG6
(C. albicans)		FCA1
(C. albicans)
Candida albicans
Reviews

Topics
Genes linked to topics(#21-30)
FCY2
(C. albicans)		HOG1
(C. albicans)		HSP90
(C. albicans)		INT1
(C. albicans)		MID1
(C. albicans)		MKC1
(C. albicans)		MNT1
(C. albicans)		MNT2
(C. albicans)		MRR1
(C. albicans)		MSH2
(C. albicans)
Candida albicans
Reviews
Jump to Summary Chart for:
  • To find other papers on a gene and topic, click on the colored ball in the appropriate box.
    displays other papers with information about that topic for that gene.
    displays other papers in CGD that are associated with that topic.
    The topic is addressed in these papers but does not describe a specific gene or chromosomal feature.

  • To go to the Locus page for a gene, click on the gene name.

Topics
Genes linked to topics(#31-40)
PGA7
(C. albicans)		PHR1
(C. albicans)		PHR2
(C. albicans)		PRA1
(C. albicans)		RBT5
(C. albicans)		RIM101
(C. albicans)		RIM21
(C. albicans)		RSR1
(C. albicans)		TAC1
(C. albicans)		TEC1
(C. albicans)
Candida albicans
Reviews

Topics
Genes linked to topics(#41-44)
TUP1
(C. albicans)		UPC2
(C. albicans)		XOG1
(C. albicans)		ZRT101
(C. albicans)
Candida albicans
Reviews
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