HARADA Kazuki

Div (Section) name/title: Health and Environmental Risk Division(Integrated Health Risk Research Section)/Researcher

Research Subject

Fiscal Year: 2025
- 27216 : Research project on the health hazard assessment considering the real-life environment and vulnerability
- 27268 : Molecular mechanisms of metabolic pathology in autistic spectrum disorder-related gene Kmt2c mutant mice
- 27269 : Identification of a releaser of gut hormones in skimmed milk
- 27270 : Detection of hazards in nanoplastics by a live cell imaging platform using fluorescent protein-based indicators
- 27294 : Fundamental study of integrated health-risk evaluation
Fiscal Year: 2024
- 26829 : Research project on the health hazard assessment considering the real-life environment and vulnerability
- 26948 : Fundamental study of integrated health-risk evaluation
- 27152 : Molecular mechanisms of metabolic pathology in autistic spectrum disorder-related gene Kmt2c mutant mice
- 27153 : Identification of a releaser of gut hormones in skimmed milk

Research Result (Publication)

Original Paper
Intestinal butyric acid-mediated disruption of gut hormone secretion and lipid metabolism in vasopressin receptor-deficient mice

Presenter : HARADA K., Wada E., Osuga Y., Shimizu K., Uenoyama R., Hirai YM., Maekawa F., Miyazaki M., Hayashi KY., Nakamura K., Tsuboi T.
Title : , Molecular Metabolism, 91:102072 (2025)
Original Paper
Taurine promotes glucagon-like peptide-1 secretion in enteroendocrine L cells

Presenter : Osuga Y., HARADA K., Yamauchi T., Kitaguchi T., Hirai Y.M., Matsumoto M., Tsuboi T.
Title : , FEBS Letters (2025)
Original Paper
Immediate glucose signaling transmitted via the vagus nerve in gut–brain neural communication

Presenter : Yamada S., Natsubori A., HARADA K., Tsuboi T., Monai H.
Title : , iScience, 28(5):112439 (2025)
Original Paper
Insights into GLP-1 and insulin secretion mechanisms in pasireotide-induced hyperglycemia highlight effectiveness of Gs-targeting diabetes treatment

Presenter : Sato J., Manaka K, Horikoshi H., Taguchi M., HARADA K., Tsuboi T., Nangaku M., Makita N.
Title : , Scientific Reports, 15:9494 (2025)

Intestinal butyric acid-mediated disruption of gut hormone secretion and lipid metabolism in vasopressin receptor-deficient mice

Presenter : HARADA K., Wada E., Osuga Y., Shimizu K., Uenoyama R., Hirai YM., Maekawa F., Miyazaki M., Hayashi KY., Nakamura K., Tsuboi T.
Title : , Molecular Metabolism, 91:102072 (2025)
Taurine promotes glucagon-like peptide-1 secretion in enteroendocrine L cells

Presenter : Osuga Y., HARADA K., Yamauchi T., Kitaguchi T., Hirai Y.M., Matsumoto M., Tsuboi T.
Title : , FEBS Letters (2025)
Immediate glucose signaling transmitted via the vagus nerve in gut–brain neural communication

Presenter : Yamada S., Natsubori A., HARADA K., Tsuboi T., Monai H.
Title : , iScience, 28(5):112439 (2025)
Insights into GLP-1 and insulin secretion mechanisms in pasireotide-induced hyperglycemia highlight effectiveness of Gs-targeting diabetes treatment

Presenter : Sato J., Manaka K, Horikoshi H., Taguchi M., HARADA K., Tsuboi T., Nangaku M., Makita N.
Title : , Scientific Reports, 15:9494 (2025)

Research Result (Presentation)

Alterations in lipid metabolism and mitochondrial functions in histone methyltransferase gene Kmt2c mutant mice

Presenter : HARADA K., Nakramura T., Honda K., Takaki T., Yoshiike O.Y., Kubota S.M., Haraguchi S., Kato T., Takata A., Tsuboi T.
Name of Society : IUPS2025 (2025)
Name of Proceedings : Abstracts
Mechanisms of hypermetaboism of histone methyltransferase gene Kmt2c mutant mice

Presenter : HARADA K., Nakamura T., Honda K., Takaki T., Kubota SM., Haraguchi S., Kato T., Takata A., Tsuboi T.
Name of Society : APPW2025 (2025)
Name of Proceedings : Abstracts, 14
Investigation of hazardous effects by nanoplastic particles on intracellular signaling dynamics and respiratory functions

Presenter : HARADA K., Udagawa O., Ikuno Y., Tanaka K., Ito T., Maekawa F., Kitaguchi T., Tsuboi T., Fujitani Y.
Name of Society : Microplastics Exposure and Human Health Conference (2026)
Name of Proceedings : Abstracts, 118

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