山﨑 匡太郎

論文

• Epigenetic landscape of synthetic human centromere core regions: CENP-A assembly and euchromatic modifications interdependently antagonize heterochromatin accumulation

  Junichiro Ohzeki, Akiko Watanabe, Jia Xian Lee, Chiharu Minami, Kazuto Kugou, Kyotaro Yamazaki, Kenta Shirasawa, Sachiko Isobe, Yusuke Endo, Yasuhiro Kazuki

  Nucleic Acids Research 54(12) 2026年6月22日 査読有り
• High-throughput CRISPR live-cell imaging of low-frequency chromosomal events quantifies the latent efficiency of chromosome engineering

  Xixun Hu, Yuichiro Iwamoto, Kyotaro Yamazaki, Nanami Kishima, Natsuko Otaki, Hitomaru Miyamoto, Yuichiro Miyaoka, Yasuhiro Kazuki, Sadao Ota

  2026年5月13日
• Generation of transchromosomic mice harboring HLA-A/B/C and human B2M via mouse artificial chromosome and triple BAC integration

  Nanami Kishima, Takashi Moriwaki, Narumi Uno, Teruhiko Suzuki, Satoshi Abe, Masaki Sugawara, Yuichi Nagashima, Kanako Kazuki, Takeshi Endo, Kyotaro Yamazaki …

  Scientific Reports 15(1) 2025年7月30日 査読有り
• Development of an OATP1-humanized transchromosomic mouse model for prediction of hepatic drug uptake in humans.

  Tomoki Koishikawa, Kanako Kazuki, Rina Ohnishi, Koki Okita, Tadahaya Mizuno, Satoshi Abe, Isamu Nanchi, Yusaku Masago, Kyotaro Yamazaki, Jun-Ichiro Ohzeki …

  Drug metabolism and disposition: the biological fate of chemicals 53(2) 100028-100028 2025年2月
• Microcell-mediated chromosome transfer between non-identical human iPSCs

  Narumi Uno, Hitomaru Miyamoto, Kyotaro Yamazaki, Masaya Egawa, Hiroaki Kobayashi, Kanako Kazuki, Mitsuhiko Osaki, Teruhiko Suzuki, Shusei Hamamichi, Mitsuo Oshimura …

  Molecular Therapy - Nucleic Acids 35(4) 102382-102382 2024年12月10日 査読有り
• Generation of Monosomy 21q Human iPS Cells by CRISPR/Cas9‐Mediated Interstitial Megabase Deletion

  Masaya Egawa, Narumi Uno, Rina Komazaki, Yusuke Ohkame, Kyotaro Yamazaki, Chihiro Yoshimatsu, Yuki Ishizu, Yusaku Okano, Hitomaru Miyamoto, Mitsuhiko Osaki …

  Genes to Cells 2024年11月24日 査読有り
• Rapid human genomic DNA cloning into mouse artificial chromosome via direct chromosome transfer from human iPSC and CRISPR/Cas9-mediated translocation.

  Hitomaru Miyamoto, Hiroaki Kobayashi, Nanami Kishima, Kyotaro Yamazaki, Shusei Hamamichi, Narumi Uno, Satoshi Abe, Yosuke Hiramuki, Kanako Kazuki, Kazuma Tomizuka …

  Nucleic acids research 2024年1月5日 査読有り
• Co-treatment of CHO cells with Taxol and reversine improves micronucleation and microcell-mediated chromosome transfer efficiency

  Narumi Uno, Hiroyuki Satofuka, Hitomaru Miyamoto, Kazuhisa Honma, Teruhiko Suzuki, Kyotaro Yamazaki, Ryota Ito, Takashi Moriwaki, Shusei Hamamichi, Kazuma Tomizuka …

  Molecular Therapy - Nucleic Acids 2023年7月 査読有り
• Characterization of human anti-EpCAM antibodies for developing an antibody–drug conjugate

  Hiroyuki Satofuka, Yayan Wang, Kyotaro Yamazaki, Shusei Hamamichi, Takeshi Fukuhara, Abdur Rafique, Nana Osako, Iori Kanazawa, Takeshi Endo, Naomi Miyake …

  Scientific Reports 13(1) 2023年3月14日 査読有り筆頭著者
• Publisher Correction: Simultaneous loading of PCR-based multiple fragments on mouse artificial chromosome vectors in DT40 cell for gene delivery.

  Kyotaro Yamazaki, Kyosuke Matsuo, Akane Okada, Narumi Uno, Teruhiko Suzuki, Satoshi Abe, Shusei Hamamichi, Nanami Kishima, Shota Togai, Kazuma Tomizuka …

  Scientific reports 13(1) 3406-3406 2023年2月28日
• Simultaneous loading of PCR-based multiple fragments on mouse artificial chromosome vectors in DT40 cell for gene delivery

  Kyotaro Yamazaki, Kyosuke Matsuo, Akane Okada, Narumi Uno, Teruhiko Suzuki, Satoshi Abe, Shusei Hamamichi, Nanami Kishima, Shota Togai, Kazuma Tomizuka …

  Scientific Reports 12(21790) 1-14 2022年12月 査読有り筆頭著者
• Efficient human-like antibody repertoire and hybridoma production in trans-chromosomic mice carrying megabase-sized human immunoglobulin loci.

  Hiroyuki Satofuka, Satoshi Abe, Takashi Moriwaki, Akane Okada, Kanako Kazuki, Hiroshi Tanaka, Kyotaro Yamazaki, Genki Hichiwa, Kayoko Morimoto, Haruka Takayama …

  Nature communications 13(1) 1841-1841 2022年4月5日 査読有り