日下部 吉男

基本情報

所属

名城大学 薬学部 薬学科

学位

博士(薬学)(2008年12月)

J-GLOBAL ID

202601020701517629

researchmap会員ID

R000108886

経歴

• 2026年4月 - 現在

  名城大学, 薬学部薬学教育開発センター, 准教授
• 2015年10月

  帝京大学薬学部, 薬物治療学研究室, 講師
• 2012年4月

  文部科学省高等教育局, 医学教育課, 技術参与
• 2009年4月

  オックスフォード大学, Department of Physics, Academic Professor
• - 2009年3月

  昭和大学薬学部薬品物理化学研究室 助手

受賞

• 2024年6月

  第123回日本皮膚科学会 優秀演題賞, 重症型薬疹に関する治療薬の開発について, 日本皮膚科学会

論文

• Phosphatidylcholine with C26:0 moiety, a precursor of a diagnostic marker for X-ALD, is synthesized by LPLAT10/LPEAT2.

  Kotaro Hama, Yuko Fujiwara, Koko Imai, Yoshio Kusakabe, Yasuhiro Hayashi, Shigeo Takashima, Shohei Azuma, Masaru Kondo, Atsushi Yamashita, Ryo Takita …

  Journal of lipid research 67(2) 100973-100973 2026年2月 査読有り
• Practicing pharmacist education based on the experiences of medical support on the cruise ship Diamond Princess.

  Yoshio Kusakabe, Yasuhiro Nakamura, Keiji Maruyama

  BMC medical education 25(1) 716-716 2025年5月16日 査読有り筆頭著者
• Baicalin target protein, Annexin A2, is a target of new antitumor drugs.

  Yoshio Kusakabe, Kazuya Matsumoto, Takahiro Tsuyuki, Yasuhiro Hayashi, Hideaki Watanabe

  Scientific reports 14(1) 21814-21814 2024年9月18日 査読有り
• Isolation and identification of the new baicalin target protein to develop flavonoid structure-based therapeutic agents.

  Yoshio Kusakabe, Shun-Suke Moriya, Toru Sugiyama, Yoshiki Miyata

  Bioorganic & medicinal chemistry 90 117362-117362 2023年7月15日 査読有り
• [Practice of Ethics Education Using a Documentary Film for Pharmacy Students].

  Yoshio Kusakabe, Yasuhiro Nakamura, Kazunari Tanigawa, Ken Karasawa, Keiji Maruyama

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 143(7) 607-616 2023年7月1日 査読有り
• Genome-wide association study identifies a new susceptibility locus in PLA2G4C for Multiple System Atrophy.

  Yasuo Nakahara, Jun Mitsui, Hidetoshi Date, Kristine Joyce Porto, Yasuhiro Hayashi, Atsushi Yamashita, Yoshio Kusakabe, Takashi Matsukawa, Hiroyuki Ishiura, Tsutomu Yasuda …

  medRxiv : the preprint server for health sciences 2023年5月2日 査読有り
• Regulation of Endothelium-Reticulum-Stress-Mediated Apoptotic Cell Death by a Polymethoxylated Flavone, Nobiletin, Through the Inhibition of Nuclear Translocation of Glyceraldehyde 3-Phosphate Dehydrogenase in Retinal Müller Cells.

  Yoshiki Miyata, Kazuya Matsumoto, Shuichi Kusano, Yoshio Kusakabe, Yoshiya Katsura, Tetsuta Oshitari, Hiroshi Kosano

  Cells 10(3) 2021年3月17日 査読有り
• Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms due to lamotrigine differs from that due to other drugs.

  Yasuya Tashiro, Hiroaki Azukizawa, Hideo Asada, Hiroyuki Niihara, Eishin Morita, Teruo Yamauchi, Yoshiko Mizukawa, Yoshio Kusakabe, Satoshi Numazawa, Miki Izumi …

  The Journal of dermatology 46(3) 226-233 2019年3月 査読有り
• A docking model of dapsone bound to HLA-B*13:01 explains the risk of dapsone hypersensitivity syndrome.

  Hideaki Watanabe, Yurie Watanabe, Yasuya Tashiro, Taisei Mushiroda, Takeshi Ozeki, Hideo Hashizume, Hirohiko Sueki, Toshinori Yamamoto, Naoko Utsunomiya-Tate, Hiroaki Gouda …

  Journal of dermatological science 88(3) 320-329 2017年12月 査読有り
• Structural insights into the reaction mechanism of S-adenosyl-L-homocysteine hydrolase.

  Yoshio Kusakabe, Masaaki Ishihara, Tomonobu Umeda, Daisuke Kuroda, Masayuki Nakanishi, Yukio Kitade, Hiroaki Gouda, Kazuo T Nakamura, Nobutada Tanaka

  Scientific reports 5 16641-16641 2015年11月17日 査読有り
• [Structural biology for developing antimalarial compounds].

  Nobutada Tanaka, Tomonobu Umeda, Yoshio Kusakabe, Masayuki Nakanishi, Yukio Kitade, Kazuo T Nakamura

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 133(5) 527-37 2013年 査読有り
• Crystallization and preliminary X-ray crystallographic analysis of human autotaxin.

  Keigo Inoue, Nobutada Tanaka, Arayo Haga, Kyohei Yamasaki, Tomonobu Umeda, Yoshio Kusakabe, Yasumitsu Sakamoto, Takamasa Nonaka, Yoshihiro Deyashiki, Kazuo T Nakamura

  Acta crystallographica. Section F, Structural biology and crystallization communications 67(Pt 4) 450-3 2011年4月1日 査読有り
• Molecular basis of fosmidomycin's action on the human malaria parasite Plasmodium falciparum.

  Tomonobu Umeda, Nobutada Tanaka, Yoshio Kusakabe, Masayuki Nakanishi, Yukio Kitade, Kazuo T Nakamura

  Scientific reports 1 9-9 2011年 査読有り
• Functional complementation and genetic deletion studies of KirBac channels: activatory mutations highlight gating-sensitive domains.

  Jennifer J Paynter, Isabelle Andres-Enguix, Philip W Fowler, Stephen Tottey, Wayland Cheng, Decha Enkvetchakul, Vassiliy N Bavro, Yoshio Kusakabe, Mark S P Sansom, Nigel J Robinson …

  The Journal of biological chemistry 285(52) 40754-61 2010年12月24日 査読有り
• Crystallization of mouse S-adenosyl-L-homocysteine hydrolase.

  Masaaki Ishihara, Yoshio Kusakabe, Tsuyoshi Ohsumichi, Nobutada Tanaka, Masayuki Nakanishi, Yukio Kitade, Kazuo T Nakamura

  Acta crystallographica. Section F, Structural biology and crystallization communications 66(Pt 3) 313-5 2010年3月1日 査読有り
• Crystallization and preliminary X-ray crystallographic study of 1-deoxy-D-xylulose 5-phosphate reductoisomerase from Plasmodium falciparum.

  Tomonobu Umeda, Nobutada Tanaka, Yoshio Kusakabe, Masayuki Nakanishi, Yukio Kitade, Kazuo T Nakamura

  Acta crystallographica. Section F, Structural biology and crystallization communications 66(Pt 3) 330-2 2010年3月1日 査読有り
• Crystallization and preliminary X-ray crystallographic study of phosphoglucose isomerase from Plasmodium falciparum.

  Ken-ichi Aoki, Nobutada Tanaka, Yoshio Kusakabe, Chiharu Fukumi, Arayo Haga, Masayuki Nakanishi, Yukio Kitade, Kazuo T Nakamura

  Acta crystallographica. Section F, Structural biology and crystallization communications 66(Pt 3) 333-6 2010年3月1日 査読有り
• Structural basis for recognition of cognate tRNA by tyrosyl-tRNA synthetase from three kingdoms.

  Masaru Tsunoda, Yoshio Kusakabe, Nobutada Tanaka, Satoshi Ohno, Masashi Nakamura, Toshiya Senda, Tomohisa Moriguchi, Norio Asai, Mitsuo Sekine, Takashi Yokogawa …

  Nucleic acids research 35(13) 4289-300 2007年 査読有り
• Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors.

  Nobutada Tanaka, Arayo Haga, Noriko Naba, Katsura Shiraiwa, Yoshio Kusakabe, Kazunori Hashimoto, Tatsuyoshi Funasaka, Hisamitsu Nagase, Avraham Raz, Kazuo T Nakamura

  Journal of molecular biology 356(2) 312-24 2006年2月17日 査読有り
• Crystallization and preliminary X-ray crystallographic analysis of yeast tyrosyl-tRNA synthetase complexed with its cognate tRNA.

  Yoshio Kusakabe, Satoshi Ohno, Nobutada Tanaka, Masashi Nakamura, Masaru Tsunoda, Tomohisa Moriguchi, Norio Asai, Mitsuo Sekine, Takashi Yokogawa, Kazuya Nishikawa …

  Protein and peptide letters 13(4) 417-9 2006年 査読有り