毛利 彰宏

論文

• Convolutional neural networks detected changes in facial expressions of mice that had conditioned fear stress.

  Takatoshi Sakata, Atsushi Teramoto, Ryoya Tada, Masaya Hasegawa, Hitomi Kurahashi, Kazuo Kunisawa, Toshitaka Nabeshima, Akihiro Mouri

  Neuroscience 603 239-251 2026年5月25日
• Soy lysolecithin attenuates hypertension and behavioral impairments in mice fed a high-salt diet through receptor-specific regulation of prostaglandin signaling and arachidonic acid-derived prostaglandin production.

  Hisayoshi Kubota, Kazuo Kunisawa, Masaya Hasegawa, Hitomi Kurahashi, Kazuhiro Kagotani, Kazuki Nakajima, Yuki Fujimoto, Akihito Hayashi, Ryoji Sono, Takehiko Tsuji …

  Neurochemistry international 197 106184-106184 2026年5月14日
• Kynureninase deficiency ameliorated monocytic recruitment and severity in a mouse model of multiple sclerosis.

  Koyo Yoshidomi, Kazuo Kunisawa, Masaya Hasegawa, Yuki Kon, Aika Kosuge, Moeka Tanabe, Haruto Ojika, Yasuko Yamamoto, Hidetsugu Fujigaki, Suwako Fujigaki …

  Neurochemistry international 195 106141-106141 2026年5月
• Granulocyte-macrophage colony-stimulating factor-containing medium for blastocyst recovery culture: study protocol for a randomized controlled trial (GSET-study).

  Tatsuya Kobayashi, Kyoko Higuchi, Miki Okabe-Kinoshita, Kayoko Kikuchi, Tomoya Kurokawa, Shota Hatakeyama, Tsuyoshi Okubo, Shota Oikawa, Ryosuke Suzuki, Seiji Ogawa …

  Trials 27(1) 2026年3月13日
• Altered Cerebrospinal Fluid Tryptophan-Kynurenine Pathway Metabolism in Multiple System Atrophy.

  Ryunosuke Nagao, Kazuya Kawabata, Yasuaki Mizutani, Sayuri Shima, Akihiro Ueda, Mizuki Ito, Yasuhiro Maeda, Akihiro Mouri, Hirohisa Watanabe

  Movement disorders : official journal of the Movement Disorder Society 2026年2月2日
• Targeting the noradrenergic‐metabolic axis: A new strategy for sugar‐induced depression subtypes

  Takatoshi Sakata, Kazuo Kunisawa, Masaya Hasegawa, Yumiko Seto, Aoi Ogawa, Hitomi Kurahashi, Yasuko Yamamoto, Masao Takemura, Hidetoshi Matunami, Tomoya Sugai …

  British Journal of Pharmacology 183(9) 2099-2122 2025年12月21日
• 1‐Kestose Prevents Psychiatric‐Like Behavior by Enhancing Short‐Chain Fatty Acid Production

  Moeka Tanabe, Kazuo Kunisawa, Tadashi Fujii, Takumi Tochio, Yoshiki Hirooka, Haruto Ojika, Yuta Naruoka, Hiroyasu Ito, Kuniaki Saito, Toshitaka Nabeshima …

  Journal of Neurochemistry 169(11) e70273 2025年11月20日
• Chronic Hyponatremia Potentiates Innate Anxiety-Like Behaviors Through the Dysfunction of Monoaminergic Neurons in Mice.

  Haruki Fujisawa, Nobuhiko Magara, Shogo Nakayama, Sachiho Fuse, Naoko Iwata, Masaya Hasegawa, Hisayoshi Kubota, Hirotaka Shoji, Satoko Hattori, Hideo Hagihara …

  Molecular neurobiology 62(9) 12078-12093 2025年5月14日
• High-cellulose diet ameliorates cognitive impairment by modulating gut microbiota and metabolic pathways in mice

  Moeka Tanabe, Kazuo Kunisawa, Imari Saito, Haruto Ojika, Kuniaki Saito, Toshitaka Nabeshima, Akihiro Mouri

  The Journal of Nutrition 155(6) 1689-1699 2025年4月
• A RHO-KINASE 2 SELECTIVE INHIBITOR KD025 AMELIORATES SCHIZOPHRENIA-LIKE BEHAVIORS IN MK-801-TREATED MICE

  *Rinako Tanaka, Yue Liu, Jingzhu Liao, Akihiro Mouri, Taku Nagai, Toshitaka Nabeshima, Kozo Kaibuchi, Daiki Tachibana, Yohei Kobayashi, Norio Ozaki …

  International Journal of Neuropsychopharmacology 28(Supplement_1) i51-i52 2025年2月12日
• Chronic stress induces behavioural changes through increased kynurenic acid by downregulation of kynurenine‐3‐monooxygenase with microglial decline

  Masaya Hasegawa, Kazuo Kunisawa, Bolati Wulaer, Hisayoshi Kubota, Hitomi Kurahashi, Takatoshi Sakata, Honomi Ando, Suwako Fujigaki, Hidetsugu Fujigaki, Yasuko Yamamoto …

  British Journal of Pharmacology 182(7) 1466-1486 2024年12月10日
• Maternal immune activation induces neurodevelopmental impairments of adult offspring through alterations in tryptophane-kynurenine pathway in the placenta

  Masaya Hasegawa, Moe Niijima, Kazuo Kunisawa, Tomoaki Teshigawara, Hisayoshi Kubota, Suwako Fujigaki, Hidetsugu Fujigaki, Yasuko Yamamoto, Hyoung-Chun Kim, Kuniaki Saito …

  Biochemical and Biophysical Research Communications 737 150922-150922 2024年12月
• Adolescent social isolation decreases colonic goblet cells and impairs spatial cognition through the reduction of cystine

  Moeka Tanabe, Kazuo Kunisawa, Imari Saito, Aika Kosuge, Hiroyuki Tezuka, Tomoki Kawai, Yuki Kon, Koyo Yoshidomi, Akari Kagami, Masaya Hasegawa …

  Molecular Psychiatry 30(5) 2137-2151 2024年11月29日
• Autism spectrum disorder-like behaviors induced by hyper-glutamatergic NMDA receptor signaling through hypo-serotonergic 5-HT1A receptor signaling in the prefrontal cortex in mice exposed to prenatal valproic acid

  Hitomi Kurahashi, Kazuo Kunisawa, Kenji F. Tanaka, Hisayoshi Kubota, Masaya Hasegawa, Mai Miyachi, Yuka Moriya, Yoichi Hasegawa, Taku Nagai, Kuniaki Saito …

  Neuropsychopharmacology 50(5) 739-750 2024年10月11日
• Antipsychotic-like effects of the selective Rho-kinase 2 inhibitor KD025 in genetic and pharmacological mouse models of schizophrenia

  Rinako Tanaka, Jingzhu Liao, Yue Liu, Wenjun Zhu, Kisa Fukuzawa, Masamichi Kondo, Masahito Sawahata, Daisuke Mori, Akihiro Mouri, Hisayoshi Kubota …

  Molecular psychiatry 31(8) 4589-4601 2024年9月21日
• Soy lysolecithin prevents hypertension and cognitive impairment induced in mice by high salt intake by inhibiting intestinal inflammation.

  Hisayoshi Kubota, Kazuo Kunisawa, Masaya Hasegawa, Hitomi Kurahashi, Kazuhiro Kagotani, Yuki Fujimoto, Akihito Hayashi, Ryoji Sono, Takehiko Tsuji, Kuniaki Saito …

  Neurochemistry international 180 105858-105858 2024年9月12日
• Ido2 Deficiency Exacerbates Motor Impairment and Reduces Aryl Hydrocarbon Receptor Activity through Decreased Kynurenine in a Chronic Demyelinating Mouse Model

  Kazuo Kunisawa, Mitsuki Hara, Koyo Yoshidomi, Yuki Kon, Yasuko Yamamoto, Suwako Fujigaki, Bolati Wulaer, Aika Kosuge, Moeka Tanabe, Sei Saitoh …

  Molecular Neurobiology 62(1) 109-122 2024年6月3日
• Social Behavior in Animal Models of Autism Spectrum Disorder

  Hitomi Kurahashi, Kazuo Kunisawa, Akihiro Mouri

  Methods in Molecular Biology 2794 331-340 2024年4月18日
• 社会的隔離ストレスによる大腸杯細胞の減少は腸内細菌叢を変容させ,空間認知機能障害を誘発する

  國澤 和生, 田辺 萌夏, 齋藤 いまり, 小菅 愛加, 河合 智貴, 窪田 悠力, 齋藤 邦明, 鍋島 俊隆, 毛利 彰宏

  腸内細菌学雑誌 38(2) 120-120 2024年4月
• Chronic social defeat stress induces the down‐regulation of the Nedd4L‐GLT‐1 ubiquitination pathway in the prefrontal cortex of mice

  Aika Kosuge, Kazuo Kunisawa, Tsubasa Iida, Bolati Wulaer, Tomoki Kawai, Moeka Tanabe, Kuniaki Saito, Toshitaka Nabeshima, Akihiro Mouri

  Journal of Neurochemistry 168(9) 2479-2494 2024年3月18日