マクファーソン トム

論文

• Inside insight: decoding how insight emerges from competing world models

  Kengo Inutsuka, Tadaaki Nishioka, Tom Macpherson, Mana Fujiwara, Takatoshi Hikida, Honda Naoki

  2026年5月26日
• Essential Roles of Heparan Sulfate Endosulfatase Sulf1 in Reward and Aversion Learning Through Distinct Dopamine D1 and D2 Receptor Pathways in Male Mice.

  Ken Miya, Kent Ohta, Kazuko Keino-Masu, Takuya Okada, Seiya Mizuno, Satoru Takahashi, Tom Macpherson, Takatoshi Hikida, Masayuki Masu

  Journal of neurochemistry 170(1) e70338 2026年1月 査読有り
• Flexible value coding in the mesolimbic dopamine system depending on internal water and sodium balance.

  Takaaki Ozawa, Issei Nakagawa, Yuuki Uchida, Mayuka Abe, Tom Macpherson, Yuichi Yamashita, Takatoshi Hikida

  NPJ science of food 9(1) 197-197 2025年9月30日 査読有り
• 味覚情報伝達の分子・神経機構 味覚の相乗作用と情動生成を司るトップダウン神経回路

  小澤 貴明, 尾山 賀信, 柴田 智弘, 阿部 万友佳, 後藤 健太朗, 米丸 ひなの, 松本 悠真, 岩本 涼太郎, 櫻井 航輝, マクファーソン・トム …

  Journal of Oral Biosciences Supplement 2024 [US13-04] 2024年11月
• Sex-dependent differences in the ability of nicotine to modulate discrimination learning and cognitive flexibility in mice.

  Yoshiatsu Aomine, Yuto Shimo, Koki Sakurai, Mayuka Abe, Tom Macpherson, Takaaki Ozawa, Takatoshi Hikida

  Journal of neurochemistry 2024年9月17日 査読有り
• Clozapine N-oxide, compound 21, and JHU37160 do not influence effortful reward-seeking behavior in mice

  Yoshiatsu Aomine, Yoshinobu Oyama, Koki Sakurai, Tom Macpherson, Takaaki Ozawa, Takatoshi Hikida

  Psychopharmacology 2023年10月 査読有り
• α4-containing GABA_Areceptors on DRD2-neurons of the nucleus accumbens mediate instrumental responding for conditioned reinforcers, and its potentiation by cocaine

  Tom Macpherson, Claire I. Dixon, Jonathan Robertson, Marsha M. Sindarto, Patricia H. Janak, Delia Belelli, Jeremy J. Lambert, David N. Stephens, Sarah L. King

  eNeuro ENEURO.0236-23.2023 2023年8月8日 査読有り筆頭著者責任著者
• Dual roles for nucleus accumbens core dopamine D1-expressing neurons projecting to the substantia nigra pars reticulata in limbic and motor control in male mice

  Suthinee Attachaipanich, Takaaki Ozawa, Tom Macpherson, Takatoshi Hikida

  eNeuro ENEURO.0082-23.2023 2023年5月26日 査読有り最終著者責任著者
• Error-related signaling in nucleus accumbens D2 receptor-expressing neurons guides inhibition-based choice behavior in mice

  Tadaaki Nishioka, Suthinee Attachaipanich, Kosuke Hamaguchi, Michael Lazarus, Alban de Kerchove d’Exaerde, Tom Macpherson, Takatoshi Hikida

  Nature Communications 14(1) 2023年4月21日 査読有り最終著者責任著者
• Circuit, molecular, and developmental mechanisms in decision-making behavior

  Tom Macpherson, Minae Niwa, Hirofumi Morishita, Takatoshi Hikida

  Frontiers in Neuroscience 17 1192237-1192237 2023年4月 査読有り筆頭著者責任著者
• D1およびD2ドーパミン受容体を介する神経伝達による運動制御と学習記憶の仕組みの理解

  齊藤 奈英, 板倉 誠, 田井中 一貴, マクファーソン トム, 疋田 貴俊, 山口 瞬, 佐藤 朝子, 大久保 直, 知見 聡美, 南部 篤 …

  日本生物学的精神医学会誌 33(3) 100-105 2022年9月 査読有り
• Importin α3 (KPNA3) Deficiency Augments Effortful Reward-Seeking Behavior in Mice

  Yoshiatsu Aomine, Koki Sakurai, Tom Macpherson, Takaaki Ozawa, Yoichi Miyamoto, Yoshihiro Yoneda, Masahiro Oka, Takatoshi Hikida

  Frontiers in Neuroscience 16 905991-905991 2022年6月30日 査読有り
• Nucleus Accumbens Core Dopamine D2 Receptor-Expressing Neurons Control Reversal Learning but Not Set-Shifting in Behavioral Flexibility in Male Mice

  Tom Macpherson, Ji Yoon Kim, Takatoshi Hikida

  Frontiers in Neuroscience 16 2022年6月28日 査読有り筆頭著者責任著者
• Error-related Signaling in Nucleus Accumbens D2 Receptor-expressing Neurons Guides Avoidance-based Goal-directed Behavior

  Tadaaki Nishioka, Tom Macpherson, Kosuke Hamaguchi, Takatoshi Hikida

  Research Square 2022年1月5日 最終著者責任著者
• Natural and Artificial Intelligence: A brief introduction to the interplay between AI and neuroscience research.

  Tom Macpherson, Anne Churchland, Terry Sejnowski, James DiCarlo, Yukiyasu Kamitani, Hidehiko Takahashi, Takatoshi Hikida

  Neural networks : the official journal of the International Neural Network Society 144 603-613 2021年12月 査読有り筆頭著者
• Parallel and hierarchical neural mechanisms for adaptive and predictive behavioral control

  Tom Macpherson, Masayuki Matsumoto, Hiroaki Gomi, Jun Morimoto, Eiji Uchibe, Takatoshi Hikida

  Neural Networks 144 507-521 2021年9月 査読有り筆頭著者
• Distinct Roles of Dopamine D1 and D2 Receptor-expressing Neurons in the Nucleus Accumbens for a Strategy Dependent Decision Making

  Tadaaki Nishioka, Tom Macpherson, Kosuke Hamaguchi, Takatoshi Hikida

  BioRxiv 2021年8月5日
• Effects of Importin α1/KPNA1 deletion and adolescent social isolation stress on psychiatric disorder-associated behaviors in mice.

  Koki Sakurai, Taichi Itou, Makiko Morita, Emiko Kasahara, Tetsuji Moriyama, Tom Macpherson, Takaaki Ozawa, Yoichi Miyamoto, Yoshihiro Yoneda, Atsuo Sekiyama …

  PloS one 16(11) e0258364 2021年 査読有り
• Neurotransmission through dopamine D1 receptors is required for aversive memory formation and Arc activation in the cerebral cortex.

  Nae Saito, Kazuki Tainaka, Tom Macpherson, Takatoshi Hikida, Shun Yamaguchi, Toshikuni Sasaoka

  Neuroscience research 156 58-65 2020年5月5日 査読有り
• Nucleus accumbens pathways control cell-specific gene expression in the medial prefrontal cortex.

  Takatoshi Hikida, Shuhei Yao, Tom Macpherson, Ayumi Fukakusa, Makiko Morita, Haruhide Kimura, Keisuke Hirai, Tatsuya Ando, Hiroyoshi Toyoshiba, Akira Sawa

  Scientific reports 10(1) 1838-1838 2020年2月4日 査読有り筆頭著者