岡本 仁

論文

• The neural pathway from the superior subpart of the medial habenula to the interpeduncular nucleus suppresses anxiety

  Takehisa Handa, Taku Sugiyama, Tanvir Islam, Joshua P. Johansen, Yuchio Yanagawa, Thomas J. McHugh, Hitoshi Okamoto

  Molecular Psychiatry 2025年8月
• The habenula-interpeduncular nucleus-median raphe pathway regulates the outcome of social dominance conflicts in mice

  Miho Matsumata, Kenzo Hirao, Takuma Kobayashi, Takehisa Handa, Yijun Zhou, Taku Sugiyama, Hisaya Kakinuma, Tanvir Islam, Yuki Kobayashi, Arthur J. Huang …

  Current Biology 35(9) 2064-2077.e9 2025年5月
• Establishment and genetic characterization of zebrafish RW line

  Kenichiro Sadamitsu, Makoto Kashima, Seiji Wada, Akiko Ishioka, Satomi Nakayama, Ryoko Nakayama, Hitoshi Okamoto, Hiromi Hirata

  Scientific Reports 15(1) 2025年4月25日
• Swimming Into Future Breakthroughs From Kyoto, Japan: Report of the 18th International Zebrafish Conference (IZFC2024)

  Hiromi Hirata, Tohru Ishitani, Hitoshi Okamoto

  Genes to Cells 2025年1月
• Mammalian genome research resources available from the National BioResource Project in Japan

  Saori Mizuno-Iijima, Shoko Kawamoto, Masahide Asano, Tomoji Mashimo, Shigeharu Wakana, Katsuki Nakamura, Ken-ichi Nishijima, Hitoshi Okamoto, Kuniaki Saito, Sawako Yoshina …

  Mammalian Genome 2024年12月
• Adult zebrafish can learn Morris water maze-like tasks in a two-dimensional virtual reality system

  Tanvir Islam, Makio Torigoe, Yuki Tanimoto, Hitoshi Okamoto

  Cell Reports Methods 2024年10月
• Transgenic tools targeting the basal ganglia reveal both evolutionary conservation and specialization of neural circuits in zebrafish.

  Yuki Tanimoto, Hisaya Kakinuma, Ryo Aoki, Toshiyuki Shiraki, Shin-Ichi Higashijima, Hitoshi Okamoto

  Cell reports 113916-113916 2024年3月8日
• The serotonergic neurons derived from rhombomere 2 are localized in the median raphe and project to the dorsal pallium in zebrafish.

  Kotaro Shibayama, Haruna Nakajo, Yuki Tanimoto, Hisaya Kakinuma, Toshiyuki Shiraki, Takashi Tsuboi, Hitoshi Okamoto

  Neuroscience research 2024年3月5日
• Acetylcholine potentiates glutamate transmission from the habenula to the interpeduncular nucleus in losers of social conflict

  Masae Kinoshita, Hitoshi Okamoto

  Current Biology 2023年6月
• Identification of a functional susceptibility variant for adolescent idiopathic scoliosis that upregulates EGR1-mediated UNCX expression.

  Yoshiro Yonezawa, Long Guo, Hisaya Kakinuma, Nao Otomo, Soichiro Yoshino, Kazuki Takeda, Masahiro Nakajima, Toshiyuki Shiraki, Yoji Ogura, Yohei Takahashi …

  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 38(1) 144-153 2022年11月7日
• Zebrafish capable of generating future state prediction error show improved active avoidance behavior in virtual reality

  Makio Torigoe, Tanvir Islam, Hisaya Kakinuma, Chi Chung Alan Fung, Takuya Isomura, Hideaki Shimazaki, Tazu Aoki, Tomoki Fukai, Hitoshi Okamoto

  Nature Communications 12(1) 2021年9月29日 査読有り責任著者
• Protein fucosylation is required for Notch dependent vascular integrity in zebrafish.

  Gerissa Fowler, Danielle French, April Rose, Paige Squires, Catarina Anecito da Silva, Shinya Ohata, Hitoshi Okamoto, Curtis R French

  Developmental biology 2021年8月13日 査読有り
• Habenula as the experience-dependent controlling switchboard of behavior and attention in social conflict and learning

  Okamoto, H., Cherng, B.-W., Nakajo, H., Chou, M.-Y., Kinoshita, M.

  Current Opinion in Neurobiology 68 2021年
• The Dorsal Lateral Habenula-Interpeduncular Nucleus Pathway Is Essential for Left-Right-Dependent Decision Making in Zebrafish

  Bor-Wei Cherng, Tanvir Islam, Makio Torigoe, Takashi Tsuboi, Hitoshi Okamoto

  Cell Reports 32(11) 108143-108143 2020年9月 査読有り責任著者
• Hunger Potentiates the Habenular Winner Pathway for Social Conflict by Orexin-Promoted Biased Alternative Splicing of the AMPA Receptor Gene.

  Haruna Nakajo, Ming-Yi Chou, Masae Kinoshita, Lior Appelbaum, Hideaki Shimazaki, Takashi Tsuboi, Hitoshi Okamoto

  Cell reports 31(12) 107790-107790 2020年6月23日 査読有り責任著者
• In-vivo imaging of the telencephalic neural activities in the closed-loop virtual reality environment revealed active inference in decision making

  Hitoshi Okamoto, Makio Torigoe

  IBRO Reports 6 S48-S48 2019年9月 査読有り責任著者
• Future state prediction errors guide active avoidance behavior by adult zebrafish.

  Makio Torigoe, Tanvir Islam, Hisaya Kakinuma, Chi Chung Alan Fung, Takuya Isomura, Hideaki Shimazaki, Tazu Aoki, Tomoki Fukai, Hitoshi Okamoto

  bioRxiv 10.1101/546440 2019年2月 責任著者
• Wide and Deep Imaging of Neuronal Activities by a Wearable NeuroImager Reveals Premotor Activity in the Whole Motor Cortex

  Kobayashi, T., Islam, T., Sato, M., Ohkura, M., Nakai, J., Hayashi, Y., Okamoto, H.

  Scientific Reports 9(1) 2019年
• Wide and Deep Imaging of Neuronal Activities by a Wearable NeuroImager Reveals Premotor Activity in the Whole Motor Cortex

  Kobayashi, T., Islam, T., Sato, M., Ohkura, M., Nakai, J., Hayashi, Y., Okamoto, H.

  Scientific Reports 9(1) 2019年
• The behavioral paradigm to induce repeated social defeats in zebrafish

  Haruna Nakajo, Takashi Tsuboi, Hitoshi Okamoto

  Neuroscience Research 2019年 査読有り責任著者