川辺 浩志

論文

• The E3 ubiquitin ligase Nedd4L preserves skeletal muscle stem cell quiescence by inhibiting their activation

  Darren M. Blackburn, Korin Sahinyan, Aldo Hernández-Corchado, Felicia Lazure, Vincent Richard, Laura Raco, Gabrielle Perron, René P. Zahedi, Christoph H. Borchers, Christoph Lepper …

  iScience 27(7) 110241-110241 2024年7月
• Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity

  Bekir Altas, Hong Jun Rhee, Anes Ju, Hugo Solís, Samir Karaca, Jan Winchenbach, Oykum Kaplan-Arabaci, Manuela Schwark, Mateusz Ambrozkiewicz, ChungKu Lee …

  Journal of Cell Biology 11(1) 2023年11月 査読有り最終著者
• Impacts of methotrexate on survival, dendrite development, and synapse formation of cortical neurons.

  Mai Yamamura, Kenji Hanamura, Noriko Koganezawa, Senami Furubayashi, Tomoaki Shirao, Hiroshi Kawabe

  Genes to cells : devoted to molecular & cellular mechanisms 28(8) 563-572 2023年8月
• The murine ortholog of Kaufman oculocerebrofacial syndrome gene Ube3b is crucial for the maintenance of the excitatory synapses in the young adult stage.

  Saki Katsube, Noriko Koganezawa, Kenji Hanamura, Katherine J Cuthill, Victor Tarabykin, Mateusz C Ambrozkiewicz, Hiroshi Kawabe

  Neuroscience letters 797 137059-137059 2023年1月7日
• Distinct but overlapping roles of LRRTM1 and LRRTM2 in developing and mature hippocampal circuits.

  Shreya H Dhume, Steven A Connor, Fergil Mills, Parisa Karimi Tari, Sarah H M Au-Yeung, Benjamin Karimi, Shinichiro Oku, Reiko T Roppongi, Hiroshi Kawabe, Shernaz X Bamji …

  eLife 11 2022年6月6日
• Global ubiquitinome profiling identifies NEDD4 as a regulator of Profilin 1 and actin remodelling in neural crest cells

  Lohraseb, I., McCarthy, P., Secker, G., Marchant, C., Wu, J., Ali, N., Kumar, S., Daly, R.J., Harvey, N.L., Kawabe, H. …

  Nature Communications 13(1) 2022年
• Super-resolved 3D-STED microscopy identifies a layer-specific increase in excitatory synapses in the hippocampal CA1 region of Neuroligin-3 KO mice.

  Noriko Koganezawa, Kenji Hanamura, Manuela Schwark, Dilja Krueger-Burg, Hiroshi Kawabe

  Biochemical and biophysical research communications 582 144-149 2021年12月10日
• NEDD4-1 is a key regulator of epidermal homeostasis and wound repair.

  Shen Yan, Raphael Ripamonti, Hiroshi Kawabe, Maya Ben-Yehuda Greenwald, Sabine Werner

  The Journal of investigative dermatology 2021年10月28日
• Congenital deletion of nedd4‐2 in lung epithelial cells causes progressive alveolitis and pulmonary fibrosis in neonatal mice

  Leitz, D.H.W., Duerr, J., Mulugeta, S., Agircan, A.S., Zimmermann, S., Kawabe, H., Dalpke, A.H., Beers, M.F., Mall, M.A.

  International Journal of Molecular Sciences 22(11) 6146-6146 2021年6月7日
• The role of E3 ubiquitin ligases in synapse function in the healthy and diseased brain.

  Hiroshi Kawabe, Judith Stegmüller

  Molecular and cellular neurosciences 112 103602-103602 2021年4月
• Molecular Evolution, Neurodevelopmental Roles and Clinical Significance of HECT-Type UBE3 E3 Ubiquitin Ligases.

  Mateusz C Ambrozkiewicz, Katherine J Cuthill, Dermot Harnett, Hiroshi Kawabe, Victor Tarabykin

  Cells 9(11) 2020年11月10日
• The Daam2-VHL-Nedd4 axis governs developmental and regenerative oligodendrocyte differentiation.

  Xiaoyun Ding, Juyeon Jo, Chih-Yen Wang, Carlo D Cristobal, Zhongyuan Zuo, Qi Ye, Marvin Wirianto, Aaron Lindeke-Myers, Jong Min Choi, Carrie A Mohila …

  Genes & development 34(17-18) 1177-1189 2020年9月1日
• Structural and Functional Refinement of the Axon Initial Segment in Avian Cochlear Nucleus during Development.

  Nargis Akter, Ryota Fukaya, Ryota Adachi, Hiroshi Kawabe, Hiroshi Kuba

  The Journal of neuroscience : the official journal of the Society for Neuroscience 40(35) 6709-6721 2020年8月26日
• Conditional deletion of Nedd4-2 in lung epithelial cells causes progressive pulmonary fibrosis in adult mice.

  Julia Duerr, Dominik H W Leitz, Magdalena Szczygiel, Dmytro Dvornikov, Simon G Fraumann, Clemens Kreutz, Piotr K Zadora, Ayça Seyhan Agircan, Philip Konietzke, Theresa A Engelmann …

  Nature communications 11(1) 2012-2012 2020年4月24日
• Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors.

  Lin Luo, Mateusz C Ambrozkiewicz, Fritz Benseler, Cui Chen, Emilie Dumontier, Susanne Falkner, Elisabetta Furlanis, Andrea M Gomez, Naosuke Hoshina, Wei-Hsiang Huang …

  Neuron 106(1) 37-65 2020年4月8日 査読有り
• The murine ortholog of Kaufman oculocerebrofacial syndrome protein Ube3b regulates synapse number by ubiquitinating Ppp3cc.

  Mateusz C Ambrozkiewicz, Ekaterina Borisova, Manuela Schwark, Silvia Ripamonti, Theres Schaub, Alina Smorodchenko, A Ioana Weber, Hong Jun Rhee, Bekir Altas, Rüstem Yilmaz …

  Molecular psychiatry 2020年4月6日
• WWP1 knockout in mice exacerbates obesity-related phenotypes in white adipose tissue but improves whole-body glucose metabolism.

  Shunsuke Hoshino, Masaki Kobayashi, Ryoma Tagawa, Ryutaro Konno, Takuro Abe, Kazuhiro Furuya, Kumi Miura, Hiroki Wakasawa, Naoyuki Okita, Yuka Sudo …

  FEBS open bio 10(3) 306-315 2020年3月
• Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140.

  Ambrozkiewicz MC, Schwark M, Kishimoto-Suga M, Borisova E, Hori K, Salazar-Lázaro A, Rusanova A, Altas B, Piepkorn L, Bessa P …

  Neuron 100(5) 1097-1115.e15 2018年12月 査読有り
• Molecular mechanisms of Streptococcus pneumoniae-targeted autophagy via pneumolysin, Golgi-resident Rab41, and Nedd4-1-mediated K63-linked ubiquitination.

  Michinaga Ogawa, Ryuta Matsuda, Naoki Takada, Mikado Tomokiyo, Shouji Yamamoto, Sayaka Shizukusihi, Toshiyuki Yamaji, Yuko Yoshikawa, Mitsutaka Yoshida, Isei Tanida …

  Cellular microbiology 20(8) e12846 2018年8月 査読有り
• Deletion of LRRTM1 and LRRTM2 in adult mice impairs basal AMPA receptor transmission and LTP in hippocampal CA1 pyramidal neurons.

  Mehdi Bhouri, Wade Morishita, Paul Temkin, Debanjan Goswami, Hiroshi Kawabe, Nils Brose, Thomas C Südhof, Ann Marie Craig, Tabrez J Siddiqui, Robert Malenka

  Proceedings of the National Academy of Sciences of the United States of America 115(23) E5382-E5389-E5389 2018年6月5日 査読有り