Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

ALK Y1239H [plasma membrane] Show undefined attributes

candidateOf

[CandidateSet:R-HSA-9700083] kinase domain ALK mutants [plasma membrane] - Homo sapiens

compartment

[Compartment:876] plasma membrane

componentOf

created [InstanceEdit:9715264] Rothfels, Karen, 2021年02月17日

crossReference

[DatabaseIdentifier:11944985] Mondo:0020325

dbId 9715266

disease

[Disease:9699595] anaplastic large cell lymphoma

displayName ALK Y1239H [plasma membrane]

endCoordinate 1620

hasModifiedResidue

[ReplacedResidue:9715217] L-tyrosine 1239 replaced with L-histidine

inDisease true

literatureReference

[LiteratureReference:9715255] Identification of oncogenic point mutations and hyperphosphorylation of anaplastic lymphoma kinase in lung cancer

maxDepth 1

name

ALK Y1239H
ALK tyrosine kinase receptor
ALK_HUMAN

referenceEntity [ReferenceGeneProduct:uniprot:Q9UM73] UniProt:Q9UM73 ALK

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-9715266

startCoordinate 19

Referrals

(hasCandidate)

[CandidateSet:R-HSA-9700083] kinase domain ALK mutants [plasma membrane]

(hasComponent)

[Complex:R-HSA-9715318] ALK Y1239H dimer [plasma membrane]

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