Reactome Pathway Database

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kinase domain ALK mutants [plasma membrane] Show undefined attributes

compartment

[Compartment:876] plasma membrane

created [InstanceEdit:9700089] Rothfels, Karen, 2020年09月14日

crossReference

[DatabaseIdentifier:11944892] Mondo:0004992

dbId 9700083

disease

[Disease:1500689] cancer

displayName kinase domain ALK mutants [plasma membrane]

hasCandidate

hasMember

inDisease true

literatureReference

[LiteratureReference:9699668] Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain
[LiteratureReference:9713917] Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer
[LiteratureReference:9700357] Treatment Efficacy and Resistance Mechanisms Using the Second-Generation ALK Inhibitor AP26113 in Human NPM-ALK-Positive Anaplastic Large Cell Lymphoma

maxDepth 2

memberOf

[DefinedSet:R-HSA-9700567] ALK point mutants [plasma membrane] - Homo sapiens

modified [InstanceEdit:9730954] Rothfels, Karen, 2021年05月12日

name

kinase domain ALK mutants

schemaClass CandidateSet

species

[Species:48887] Homo sapiens

stId R-HSA-9700083

Referrals

(hasMember)

[DefinedSet:R-HSA-9700567] ALK point mutants [plasma membrane]

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