Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

ALK I1171N [plasma membrane] Show undefined attributes

compartment

[Compartment:876] plasma membrane

componentOf

created [InstanceEdit:9699845] Rothfels, Karen, 2020年09月14日

crossReference

dbId 9699828

disease

displayName ALK I1171N [plasma membrane]

endCoordinate 1620

hasModifiedResidue

[ReplacedResidue:9699855] L-isoleucine 1171 replaced with L-asparagine

inDisease true

literatureReference

[LiteratureReference:9700339] Crizotinib-resistant NPM-ALK mutants confer differential sensitivity to unrelated Alk inhibitors

maxDepth 1

memberOf

[CandidateSet:R-HSA-9700083] kinase domain ALK mutants [plasma membrane] - Homo sapiens

modified [InstanceEdit:9700452] Rothfels, Karen, 2020年09月16日

name

ALK I1171N
ALK tyrosine kinase receptor
ALK_HUMAN

referenceEntity [ReferenceGeneProduct:uniprot:Q9UM73] UniProt:Q9UM73 ALK

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-9699828

startCoordinate 19

Referrals

(hasMember)

[CandidateSet:R-HSA-9700083] kinase domain ALK mutants [plasma membrane]

(hasComponent)

[Complex:R-HSA-9700533] ALK I1171N dimer [plasma membrane]

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