Reactome | Trimmed spike protein binds to calnexin

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Trimmed spike protein binds to calnexin Show undefined attributes

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authored

[InstanceEdit:9683645] Stephan, Ralf, 2020年04月08日

catalystActivity

[CatalystActivity:9682842] unfolded protein binding activity of CANX [endoplasmic reticulum lumen]

category transition

compartment

[Compartment:17957] endoplasmic reticulum lumen

created [InstanceEdit:9683729] Stephan, Ralf, 2020年04月17日

crossReference

[DatabaseIdentifier:11944911] Mondo:0005091

dbId 9683772

disease

[Disease:9678120] severe acute respiratory syndrome

displayName Trimmed spike protein binds to calnexin

edited

[InstanceEdit:9689806] D'Eustachio, Peter, 2020年05月21日

eventOf

[Pathway:R-HSA-9683686] Maturation of spike protein - Homo sapiens

followingEvent

[Reaction:R-HSA-9683653] Spike protein gets palmitoylated - Homo sapiens

input

[EntityWithAccessionedSequence:R-COV-9683716] trimmed unfolded N-glycan Spike [endoplasmic reticulum lumen]

isChimeric false

isInDisease true

isInferred false

literatureReference

[LiteratureReference:9682911] Monitoring of S protein maturation in the endoplasmic reticulum by calnexin is important for the infectivity of severe acute respiratory syndrome coronavirus

maxDepth 1

modified [InstanceEdit:9937650] Stephan, Ralf, 2025年02月05日

name

Trimmed spike protein binds to calnexin

orthologousEvent

[Reaction:R-HSA-9694337] Trimmed spike protein binds to calnexin - Homo sapiens

output

[EntityWithAccessionedSequence:R-COV-9683608] trimmed N-glycan Spike [endoplasmic reticulum lumen]

precedingEvent

[BlackBoxEvent:R-HSA-9683663] N-glycan trimming of Spike - Homo sapiens

relatedSpecies

[Species:9678119] Human SARS coronavirus

releaseDate 2020年06月10日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:9690206] Acencio, Marcio Luis, Mazein, Alexander, 2020年05月27日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-9683772

summation

[Summation:9682791] Calnexin transiently binds the unfolded spike protein and pr...

Referrals

(hasEvent)

[Pathway:R-HSA-9683686] Maturation of spike protein

(precedingEvent)

[Reaction:R-HSA-9683653] Spike protein gets palmitoylated

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Trimmed spike protein binds to calnexin Show undefined attributes

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