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Search ...
Go!
Schema
>
EntityWithAccessionedSequence
>
Entries
p-6Y-ERBB2 V777L [plasma membrane]
Show undefined attributes
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compartment
[Compartment:876] plasma membrane
created
[InstanceEdit:9647197] Orlic-Milacic, Marija, 2019年05月30日
crossReference
[DatabaseIdentifier:11944899] Mondo:0005575
[DatabaseIdentifier:11945448] Mondo:0005028
[DatabaseIdentifier:11945235] Mondo:0005522
[DatabaseIdentifier:11944928] Mondo:0001056
[DatabaseIdentifier:11944925] Mondo:0009831
[DatabaseIdentifier:11945164] Mondo:0004986
[DatabaseIdentifier:11944895] Mondo:0007254
[DatabaseIdentifier:11944892] Mondo:0004992
[DatabaseIdentifier:9646581] COSMIC:COSV54062767
[DatabaseIdentifier:9646582] COSMIC:COSM3718346
[DatabaseIdentifier:9646584] COSMIC:COSV54062385
dbId
9647214
disease
[Disease:1500576] breast cancer
[Disease:1500689] cancer
[Disease:1248674] large intestine cancer
[Disease:1500687] stomach cancer
[Disease:9632339] esophagus adenocarcinoma
[Disease:3310977] small intestine carcinoma
[Disease:2328198] pancreatic cancer
[Disease:1493885] bladder carcinoma
displayName
p-6Y-ERBB2 V777L [plasma membrane]
endCoordinate
1255
hasModifiedResidue
[ReplacedResidue:9646580] L-valine 777 replaced with L-leucine
[ModifiedResidue:1248700] O4'-phospho-L-tyrosine at 1023
[ModifiedResidue:1248685] O4'-phospho-L-tyrosine at 1139
[ModifiedResidue:1248708] O4'-phospho-L-tyrosine at 1196
[ModifiedResidue:1248692] O4'-phospho-L-tyrosine at 1221
[ModifiedResidue:1248701] O4'-phospho-L-tyrosine at 1222
[ModifiedResidue:1248689] O4'-phospho-L-tyrosine at 1248
inDisease
true
literatureReference
[LiteratureReference:9646435] Activating HER2 mutations in HER2 gene amplification negative breast cancer
[LiteratureReference:9646445] Combined Blockade of Activating
ERBB2
Mutations and ER Results in Synthetic Lethality of ER+/HER2 Mutant Breast Cancer
maxDepth
1
memberOf
[CandidateSet:R-HSA-9664920] p-6Y-ERBB2 KD mutants (EGFR,PI3K) [plasma membrane] - Homo sapiens
[CandidateSet:R-HSA-9665035] p-6Y-ERBB2 KD mutants (EGFR,PLCG1) [plasma membrane] - Homo sapiens
[CandidateSet:R-HSA-9664999] p-6Y-ERBB2 KD mutants (EGFR,RAS) [plasma membrane] - Homo sapiens
[CandidateSet:R-HSA-9664610] p-6Y-ERBB2 KD mutants (EGFR,ERBB3) [plasma membrane] - Homo sapiens
name
p-6Y-ERBB2 V777L
p-6Y-HER2 V777L
p-6Y-ERBB2 Val777Leu
p-6Y-HER2 Val777Leu
referenceEntity
[ReferenceGeneProduct:uniprot:P04626] UniProt:P04626 ERBB2
referenceType
ReferenceGeneProduct
schemaClass
EntityWithAccessionedSequence
species
[Species:48887] Homo sapiens
stId
R-HSA-9647214
startCoordinate
23
Referrals
(hasMember)
[CandidateSet:R-HSA-9665035] p-6Y-ERBB2 KD mutants (EGFR,PLCG1) [plasma membrane]
[CandidateSet:R-HSA-9664920] p-6Y-ERBB2 KD mutants (EGFR,PI3K) [plasma membrane]
[CandidateSet:R-HSA-9664610] p-6Y-ERBB2 KD mutants (EGFR,ERBB3) [plasma membrane]
[CandidateSet:R-HSA-9664999] p-6Y-ERBB2 KD mutants (EGFR,RAS) [plasma membrane]
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